Abstract
Cardiovascular diseases (CVDs) in pregnancy may represent true cardiovascular syndromes that preexist before pregnancy or may manifest for the first time due to the hemodynamic changes of pregnancy, which by themselves may mimic cardiovascular diseases, even though physiological. This chapter describes the physiological basis of the hemodynamic changes in pregnancy which may mimic, precipitate, or potentiate adversity in cardiovascular diseases and discusses ways to identify true disease. It also details the spectrum of cardiac risk factors and cardiovascular diseases prevalent in the developing countries, explaining the mechanisms for causation of threats to maternal health and fetal well-being; the clinical presentation and management of the disease conditions.
It highlights the cardiovascular contraindications to pregnancy with special considerations on the management of complex cardiovascular diseases in pregnancy with a note on areas of future research.
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References
ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). Eur Heart J. 2011;32(24):3147–97.
Samuel A, Ibrahim D. Hypertension in pregnancy among rural women in Katsina State, Nigeria. J Basic Clin Reprod Sci. 2017;6(1) https://doi.org/10.4103/2278-960.194500.
John S, Olukayode D. 2016, The hypertensive disorders of pregnancy in Ogun State Nigeria. Preeclampsia in low and middle income countries. Pregnancy Hyper. 2018;6(3):209.
Singh S, Ekele BA, Egondu SC, Ikechukwu NE. Hypertensive disorders in pregnancy among pregnant women in a nigerian teaching hospital. J Nigeria Med Assoc. 2014;55(5):384–8.
Joshi G, Joshi S, Jha S, Joshi A, Singh Y. Maternal heart disease and pregnancy outcome: Findings from a retrospective cohort in a tertiary care government hospital in Haldwani, Nainital. India. Nigerian J Cardiol. 2015;12(2):120.
Karaye KM, Henein MY. Peripartum cardiomyopathy. A review article. Int J Cardiol. 2013;164:33–8.
Avila WS, Rossi EG, Ramires JA, Grinberg M, Bortolloto MR, Zugalia M da Luz PL. 2003. Hypertension in patients with heart disease. Experience with 1000 cases. Clin Cardiol. 2003;26(3):135–42.
Cardiovasculae disease and pregnancy. https://medscape.com.
Akinwusi PO, Oboro VO, Adebayo PA, Akintunde AA, Adeniji AO, Isawumi IA, et al. Cardiovascular and electrocardiographic changes in Nigerians with a normal pregnancy. Cardiovasc J Afr. 2010;21:71–5.
Thornburg KL, Jacobson S-L, Giraud GG, Morton MJ. Haemodynamic changes in pregnancy. Semin Perinatol. 2000;24(1):11–4.
Hall ME, George EM, Granger JP. The heart during pregnancy. Revista Española dCardiologÃa (English Edition). 2011;64(11):1045–50.
Braunwald’s Heart Disease: A Textbook Of Cardiovascular Medicine, 10th Edition. Eds Zipes DP, Libby P, Bonow RO, Mann DL and Tomaselli GF. IN Carole Waynes: Pregnancy and heart disease. p 1755.
Sanghavi M, Rutherford JD. Cardiovascular physiology of pregnancy; Circulation. 2014;130(12);1003–8.
Brent RL. The effect of embryonic and fetal exposure to x-ray, microwaves, and ultrasound: counseling the pregnant and nonpregnant patient about these risks. Semin Oncol. 1989;16:347–68.
Sihai BM. Treatment of hypertension in pregnancy. N Engl J Med. 1996;335:257–65.
Nithin PG. Pregnancy and Heart disease. https://slideplayer.com/slide/2320848/.
Warnes CA, Williams RG, Ashore TM, Child JS, Connolly HM, Dearani JA, et al. ACC/AHA 2008 Guidelines for management of adults with Cong Heart disease. Executive summary. Cirulation. 2008;118(23):2395–451.
Bowater SE, Thorne SA. Management of pregnancy in women with acquired and congenital heart disease. Postgrad Med J. 2010;86(1012):100–5.
Friedrich E, Hameed AB. Fluctuations in anti-factor Xa levels with therapeuticenoxaparin anticoagulation in pregnancy. J Perinatol. 2010;30:253–7.
Sliwa K, Hilfiker-Kleiner D, Petrie MC, Mebazaa A, Pieske B, Buchmann E,Regitz-Zagrosek V, Schaufelberger M, Tavazzi L, van Veldhuisen DJ,Watkins H, Shah AJ, Seferovic PM, Elkayam U, Pankuweit S, Papp Z,Mouquet F, McMurray JJ. Current state of knowledge on aetiology, diagnosis,management, and therapy of peripartum cardiomyopathy: a position statementfrom the Heart Failure Association of the European Society of CardiologyESC Guidelines 2011Working Group on peripartum cardiomyopathy. Eur J Heart Fail 2010;12:767–78.
Franklin W, Benton MK, Parekh D. Cardiac disease in pregnancy. Tex Heart Inst J. 2011;38(2):151–3.
Weiss BM, Zemp L, Seifert B, Hess OM. Outcome of pulmonary vascular disease in pregnancy: a systematic overview from 1978 through 1996. JACC. 1998;31(7):1650–7.
Bédard E, Dimopoulos K, Gatzoulis MA. Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension. Eur Heart J. 2009;30:256–65.
Silversides CK, Harris L, Haberer K, Sermer M, Colman JM, Siu SC. Recurrence rates of arrhythmias during pregnancy in women with previous tachyarrhythmia and impact on fetal and neonatal outcomes. Am J Cardiol. 2006;97(8):1206–12.
Roth Elkayam U. Acute myocardial infarction associated with pregnancy. L Am Coll Cardiol. 2008;52(3):171–80.
Nkoke C, Luchuo E. Coronary heart disease in sub-saharan Africa: still rare, misdiagnosed or underdiagnosed? Cardiovasc Diagn Ther. 2015; https://doi.org/10.3978/j.issn.2223-3652.2015.08.01.
Niemczyk NA, Bertolet M, Catov JM, Desai M, McClure C, Roberts JM, Sekikawa A, Tepper PG, Barinas-Mitchell EJ. Common carotid artery thickness increases throughout the pregnancy cycle: a prospective cohort study. BMC Pregnancy Childbirth. 2018;18:195.
Balint OH, Siu SC, Mason J, Grewal J, Wald R, Oechslin EN, et al. Cardiac outcomes after pregnancy in women with congenital heart disease. Heart. 2010;96:1656–61.
Mosca L, Benjamin EJ, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women-2011 update: a guideline from the American Heart Association. Circulation. 2011;123:1243.
Mendelson AM. Acquired heart disease in pregnancy [Internet]. Chap. 10. In: Sciarra JJ, editor. Gynaecology and obstetric: medical complications, vol. Vol 3. Haggerstown: Lippincott Williams and Wilkins; 2004. Available from: https://www.glowm.com/resources/glowm/cd/pages/about.html.
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Austine, O., Henry, A.O. (2021). Cardiovascular Diseases in Pregnancy. In: Okonofua, F., Balogun, J.A., Odunsi, K., Chilaka, V.N. (eds) Contemporary Obstetrics and Gynecology for Developing Countries . Springer, Cham. https://doi.org/10.1007/978-3-030-75385-6_24
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DOI: https://doi.org/10.1007/978-3-030-75385-6_24
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