Abstract
The patient is a 68-year-old male who reported a history of excellent health until 10 years ago, when he developed a cardiac/thromboembolic condition that required use of aspirin and clopidogrel for anticoagulation. In his first year of treatment, he unfortunately developed recurrent right-sided epistaxis. He recalled presenting to his local emergency department (ED) on multiple occasions to manage the nosebleeds, which led to multiple right-sided nasal cautery procedures. On his last ED visit, given profuse recurrent epistaxis, additional cautery of the nasal septum and right-sided nasal packing were pursued. Upon aggressive placement and advancement of the nasal packing into his right nasal cavity by the ED treatment team, the patient recalls experiencing an “unbearable, tearing sensation” and “excruciating, blistering pain” to his right face. Because of this traumatic experience, the patient was admitted and taken to the OR the following day by an otolaryngologist for additional surgical control of epistaxis. After this procedure, he learned that a large nasal septum perforation was found, and that “there was damage to his nasal turbinate” but that nothing further could be offered.
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References
Velasquez N, Thamboo A, Habib A-RR, Huang Z, Nayak JV. The Empty Nose Syndrome 6-Item Questionnaire (ENS6Q): a validated 6-item questionnaire as a diagnostic aid for empty nose syndrome patients. Int Forum Allergy Rhinol. 2017;7:64–71.
Thamboo A, et al. Defining surgical criteria for empty nose syndrome: validation of the office-based cotton test and clinical interpretability of the validated Empty Nose Syndrome 6-Item Questionnaire. Laryngoscope. 2017;127:1746–52.
Pereira C, et al. Nasoseptal perforation: from etiology to treatment. Curr Allergy Asthma Rep. 2018;18:5.
Lanier B, Kai G, Marple B, Wall GM. Pathophysiology and progression of nasal septal perforation. Ann Allergy Asthma Immunol. 2007;99:473–80.
Trimarchi M, et al. Otorhinolaryngological manifestations in granulomatosis with polyangiitis (Wegener’s). Autoimmun Rev. 2013;12:501–5.
Sozansky J, Houser SM. Pathophysiology of empty nose syndrome. Laryngoscope. 2015;125:70–4.
Meccariello G, et al. Management of idiopathic epistaxis in adults: what’s new? Acta Otorhinolaryngol Ital. 2019;39:211–9.
Womack JP, Kropa J, Stabile MJ. Epistaxis: outpatient management. Am Fam Physician. 2018;98:240–5.
Lange JL, Peeden EH, Stringer SP. Are prophylactic systemic antibiotics necessary with nasal packing? A systematic review. Am J Rhinol Allergy. 2017;31:240–7.
Chhabra N, Houser SM. The diagnosis and management of empty nose syndrome. Otolaryngol Clin N Am. 2009;42:311–30.
Bon S-DL, Horoi M, Bon OL, Hassid S. Intranasal trigeminal training in empty nose syndrome: a pilot study on 14 patients. Clin Otolaryngol. 2020;45:259–63.
Kim D-Y, Hong HR, Choi EW, Yoon SW, Jang YJ. Efficacy and safety of autologous stromal vascular fraction in the treatment of empty nose syndrome. Clin Exp Otorhinolaryngol. 2018;11:281–7.
Xu X, et al. The expansion of autologous adipose-derived stem cells in vitro for the functional reconstruction of nasal mucosal tissue. Cell Biosci. 2015;5:54.
Modrzyński M. Hyaluronic acid gel in the treatment of empty nose syndrome. Am J Rhinol Allergy. 2011;25:103–6.
Borchard NA, et al. Use of intranasal submucosal fillers as a transient implant to alter upper airway aerodynamics: implications for the assessment of empty nose syndrome. Int Forum Allergy Rhinol. 2019;9:681–7.
Thamboo A, et al. Inferior meatus augmentation procedure (IMAP) to treat empty nose syndrome: a pilot study. Otolaryngol Head Neck Surg. 2020;162:382–5.
Velasquez N, Huang Z, Humphreys IM, Nayak JV. Inferior turbinate reconstruction using porcine small intestine submucosal xenograft demonstrates improved quality of life outcomes in patients with empty nose syndrome. Int Forum Allergy Rhinol. 2015;5:1077–81.
Ma Z, Quan-Zeng, Jie-Liu, Hu G. Assessment of postsurgical outcomes between different implants in patients with empty nose syndrome: a meta-analysis. J Int Med Res. 2017;45:1939–48.
Manji J, Nayak JV, Thamboo A. The functional and psychological burden of empty nose syndrome. Int Forum Allergy Rhinol. 2018;8:707–12.
Lee T-J, et al. Evaluation of depression and anxiety in empty nose syndrome after surgical treatment. Laryngoscope. 2016;126:1284–9.
Malik J, et al. Computational fluid dynamic analysis of aggressive turbinate reductions: is it a culprit of empty nose syndrome? Int Forum Allergy Rhinol. 2019;9:891–9.
Houser SM. Empty nose syndrome associated with middle turbinate resection. Otolaryngol Head Neck Surg. 2006;135:972–3.
Li C, et al. Computational fluid dynamics and trigeminal sensory examinations of empty nose syndrome patients. Laryngoscope. 2017;127:E176–84.
Li C, et al. Investigation of the abnormal nasal aerodynamics and trigeminal functions among empty nose syndrome patients. Int Forum Allergy Rhinol. 2018;8:444–52.
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Yang, A., Dholakia, S., Kim, D., Nayak, J.V. (2022). Nasal Septum Perforation and Inferior Turbinate Avulsion/Unilateral Empty Nose Syndrome Resulting from Management of Recurrent Epistaxis. In: Chandra, R.K., Welch, K.C. (eds) Lessons Learned from Rhinologic Procedure Complications. Springer, Cham. https://doi.org/10.1007/978-3-030-75323-8_23
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