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An Overview of Ethnobotany of Berberis lycium Royle in Pakistan

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Biodiversity, Conservation and Sustainability in Asia

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Abstract

Berberis lycium is a medicinally and economically important species of the family Berberidaceae. It is found in different countries of the world. In Pakistan, the species is widely distributed in mountainous ranges, mainly in the west Himalayan region and Kashmir. In herbal formulations, it has great importance due to the presence of berberine. In the traditional system of medication, different parts of the plant have been used in the treatment of different diseases. In Azad Kashmir, its mixture is used to treat intestinal colic, pharyngitis, urine problems, jaundice, eye disease, piles, diarrhea, and ophthalmia. Pharmacological studies have shown that this plant has an antidiabetic, antimicrobial, antihyperlipidemic, hepatoprotective, and wound healing properties. All parts of the plant are of medicinal value. In Pakistan, root bark powder is taken in different forms orally. It shows antioxidant property because of anthocyanins and tannins. Further research is needed in the extraction, identification, and isolation of berberine as an active compound using root bark of Berberis lycium.

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References

  • Ahmad A, Mehmood S, Gulfraz M (2011) Bone healing properties of Berberis lyceum (Royal): a case study. Case Study Case Rep 1(1):1–5

    CAS  Google Scholar 

  • Ahmed M, Alamgeer A, Sharif T et al (2009) Effect of Berberis lycium Royle on lipid profile in alloxan induced diabetic rabbits. Ethnobot Leafl 2009(6):4

    Google Scholar 

  • Altay V, Çelik O (2011) Antakya semt pazarlarındaki bazı doÄŸal bitkilerin etnobotanik yönden araÅŸtırılması. Biyoloji Bilimleri AraÅŸtırma Dergisi 4(2):137–139

    Google Scholar 

  • Altay V, Karahan F (2012) Tayfur Sökmen Kampüsü (Antakya-Hatay) ve çevresinde bulunan bitkiler üzerine etnobotanik bir araÅŸtırma. Karadeniz Fen Bilimleri Dergisi 2(7):13–28

    Google Scholar 

  • Altay V, Karahan F, Sarcan YB, Ilçım A (2015) An ethnobotanical research on wild plants sold in Kırıkhan district (Hatay/Turkey) herbalists and local markets. Biol Divers Conserv 8(2):81–91

    Google Scholar 

  • Ana LC, Cadena G, Marten S, Ida T (2013) Use and valuation of native and introduced medicinal plant species in Campo Hermoso and Zetaquira, Boyacá Colombia. J Ethnobiol Ethnomed 9:23

    Google Scholar 

  • Arias ME, Gomez JD, Cudmani NM et al (2004) Antibacterial activity of ethanolic and aqueous extracts of Acacia aroma Gill. ex Hook et Arn. Life Sci 75(2):191–202

    CAS  PubMed  Google Scholar 

  • Arulselvan P, Fard MT, Tan WS et al (2016) Role of antioxidants and natural products in inflammation. Oxidative Med Cell Longev 2016:5276130

    Google Scholar 

  • Asif A, Kakub G, Mehmood S et al (2007) Wound healing activity of root extracts of Berberis lyceum Royle in rats. Phytother Res 21(6):589–591

    CAS  PubMed  Google Scholar 

  • Aslam M (2002) Conservation, cultivation and trade of medicinal herbs and spices in Pakistan. Int Workshop Health Chall 21:4–6

    Google Scholar 

  • Bhardwaj D, Kaushik N (2012) Phytochemical and pharmacological studies in genus Berberis. Phytochem Rev 11(4):523–542

    CAS  Google Scholar 

  • Bhattacharjee SK (2001) Berbericidaceae. Handbook of medicinal plants, 3rd edn. Pointer Publishers, Jaipur, pp 58–59

    Google Scholar 

  • Brahmananda PR (2000) Bank nationalisation: story of ad hocism and arbitrariness. Hindu Business Line

    Google Scholar 

  • Chand N, Durrani FR, Qureshi MS, Durrani Z (2007) Role of Berberis lycium in reducing serum cholesterol in broilers. Asian Australas J Anim Sci 20(4):563

    CAS  Google Scholar 

  • Choudhary MI, Rahman AU, Qayum MA (2003) Traditional systems of medicines and medicinal plants resource in Pakistan. http://jang.com.pk/thenews/oct. Accessed 20.10.2003

  • Dastagir G (2001) Medicinal plants of Mai Dhani Hill, Muzaffarabad, Azad Jammu and Kashmir. Hamdard Med 44(1):29–35

    Google Scholar 

  • Dev S (2006) Selection of prime ayurvedic plant drugs. Anamaya Publishers. ISBN:8188342351

    Google Scholar 

  • Duke JA, Ayensu ES (1985) Medicinal plants of China. Reference Publication, Inc., Algonac

    Google Scholar 

  • Girish C, Koner BC, Jayanthi S et al (2009) Hepatoprotective activity of six polyherbal formulations in paracetamol induced liver toxicity in mice. Indian J Med Res 129(5):569–579

    CAS  PubMed  Google Scholar 

  • Gulfraz M, Qadir G, Nosheen F, Parveen Z (2007) Antihyperglycemic effects of Berberis lyceum Royle in alloxan induced diabetic rats. Diabetol Croat 36(3):49–54

    Google Scholar 

  • Gulfraz M, Mehmood S, Ahmad A et al (2008) Comparison of the antidiabetic activity of Berberis lyceum root extract and berberine in alloxan-induced diabetic rats. Phytother Res 22(9):1208–1212

    CAS  PubMed  Google Scholar 

  • Halliwell B (2006) Reactive species and antioxidants. Redox biology is a fundamental theme of aerobic life. Plant Physiol 141(2):312–322

    CAS  PubMed  PubMed Central  Google Scholar 

  • Hamayun M (2003) Ethnobotanical studies of some useful shrubs and trees of District Buner, NWFP, Pakistan. Ethnobot Leafl 2003(1):12

    Google Scholar 

  • Hamzah TNT, Ozturk M, Altay V, Hakeem KH (2020) Chapter 15: Insights into the bioactive compounds of endophytic fungi in mangroves. In: Ozturk M, Egamberdieva D, Pesci M (eds) Biodiversity and biomedicine – our future. Elseiver-Academic Press, pp 277–292

    Google Scholar 

  • Hasanuzzaman SM (2006) Guide on medicinal and aromatic plants of SAARC countries. SAARC Agricultural Information Center CSAIC

    Google Scholar 

  • Hong L, Guo Z, Huang K et al (2015) Ethnobotanical study on medicinal plants used by Maonan people in China. J Ethnobiol Ethnomed 11(1):32

    PubMed  PubMed Central  Google Scholar 

  • Huang CG, Chu ZL, Wei SJ et al (2002) Effect of berberine on arachidonic acid metabolism in rabbit platelets and endothelial cells. Thromb Res 106(4–5):223–227

    CAS  PubMed  Google Scholar 

  • Imtiaz UH, Manzoor H (2003) Medicinal plants of Mansehra. Hamdard Med 36(3):69

    Google Scholar 

  • Irshad AH, Pervaiz AH, Abrar YB et al (2013) Antibacterial activity of Berberis lycium root extract. Trakia J Sci 11(1):89

    Google Scholar 

  • Karahan F, Altay V, Keskin M (2015) An ethnobotanical study on woody plants benefits from handicrafts in Antakya District (Hatay-Turkey). Int J Sci Technol Res 1(1):1–18

    Google Scholar 

  • Khan MA, Khan J, Ullah S et al (2011) Hepatoprotective effects of Berberis lycium, Galium aparine and Pistacia integerrima in carbon tetrachloride (CCl4)-treated rats. J Postgrad Med Inst (Peshawar-Pakistan) 22:2

    Google Scholar 

  • Khan T, Khan IA, Ahmed N et al (2014) Elaboration of phylogenetic studies in Berberis spp. from 4. I. Morpho-pathological data. Int J Biosci 4(11):285–293

    Google Scholar 

  • Khan I, Najeebullah S, Ali M, Shinwari ZK (2016) Phytopharmacological and ethnomedicinal uses of the genus Berberis (Berberidaceae): a review. Trop J Pharm Res 15(9):2047–2057

    CAS  Google Scholar 

  • Khan F, Szmigielski R, Gul A et al (2020) Chapter 18: Advancements in plant transgenomics approach for the biopharmaceutics and vaccines production. In: Ozturk M, Egamberdieva D, Pesci M (eds) Biodiversity and biomedicine – our future. Elseiver-Academic Press, pp 317–333

    Google Scholar 

  • Kirtikar KR, Basu BD (1999) Berberis lyceum. Indian Med Plant 1:104

    Google Scholar 

  • Kulkarni GT, Sharma VN, Agrawal S (2012) Antimicrobial and anti-inflammatory activities of bark of four plant species from Indian origin. Webmed Cent Pharm Sci 3(10):WMC002010

    Google Scholar 

  • Kumar RS, Sivakumar T, Sundaram R et al (2006) Antimicrobial and antioxidant activities of Careya arborea Roxb. Stem Bark. Iran J Pharmacol Ther 51:35–41

    Google Scholar 

  • Mahmood A, Mahmood A, Tabassum A (2011) Ethnomedicinal survey of plants from District Sialkot, Pakistan. J Appl Pharmacol 3:212–220

    Google Scholar 

  • Malik ZA, Bhat JA, Ballabha R et al (2015) Ethnomedicinal plants traditionally used in health care practices by inhabitants of Western Himalaya. J Ethnopharmacol 172:133–144

    PubMed  Google Scholar 

  • Manan A, Chand N, Khan S et al (2012) Effect of periodic supplementation of herbal infusion on the liver function and lipid profile of broiler chickens. Sarhad J Agric 28:75–82

    Google Scholar 

  • Masoodi KZ, Amin I, Mansoor S et al (2020) Chapter 11: Botanicals from the Himalayas with anticancer potential – an emphasis on Kashmir Himalayas. In: Ozturk M, Egamberdieva D, PeÅ¡ić M (eds) Biodiversity and biomedicine – our future. Academic, pp 189–234

    Google Scholar 

  • Mishra D, Singh RK, Srivastava RK (2012) Ethno-medicinal plants used to cure different diseases by rural folks and tribes of north eastern tarai districts Uttar Pradesh. Ind Res J Med Plant 6:286–299

    Google Scholar 

  • Muthu C, Ayyanar M, Rajan N, Ignacimuthu S (2006) Medicinal plants used by traditional healers in Kancheepuram District of Tamil Nadu India. J Ethnobiol Ethnomed 2:43

    PubMed  PubMed Central  Google Scholar 

  • Nanyingi MO, Mbaria JM, Lanyasunya AL et al (2008) Ethnopharmacological survey of Samburu district, Kenya. J Ethnobiol Ethnomed 4(1):14

    PubMed  PubMed Central  Google Scholar 

  • Nasri H, Baradaran A, Shirzad H, Rafieian-Kopaei M (2014) New concepts in nutraceuticals as alternative for pharmaceuticals. Int J Prev Med 5(12):1487

    PubMed  PubMed Central  Google Scholar 

  • Neag MA, Mocan A, Echeverría J et al (2018) Berberine: botanical occurrence, traditional uses, extraction methods, and relevance in cardiovascular, metabolic, hepatic, and renal disorders. Front Pharmacol 9:557

    PubMed  PubMed Central  Google Scholar 

  • Nidaullah H, Durrani FR, Ahmad S et al (2010) Aqueous extract from different medicinal plants as anticoccidial, growth promotive and immunostimulant in broilers. J Agric Biol Sci 5(1):53–59

    Google Scholar 

  • Njoroge GN, Kaibui IM, Njenga PK, Odhiambo PO (2010) Utilisation of priority traditional medicinal plants and local people’s knowledge on their conservation status in arid lands of Kenya (Mwingi District). J Ethnobiol Ethnomed 6(1):22

    PubMed  PubMed Central  Google Scholar 

  • Nostro A (2006) Activity of plant extracts and plant-derived compounds against drug-resistant microorganisms. Mod Phytomed 10:199–231

    Google Scholar 

  • Ozturk M, Hakeem KR (2018) Plant and human health – Vol. 1 – Ethnobotany and physiology. Springer, New York

    Google Scholar 

  • Ozturk M, Hakeem KR (2019a) Plant and human health – Vol. 2 – Phytochemistry and molecular aspects. Springer, New York

    Google Scholar 

  • Ozturk M, Hakeem KR (2019b) Plant and human health – Vol. 3 – Phytochemistry and therapeutic uses. Springer, New York

    Google Scholar 

  • Ozturk M, Altay V, Gucel S, Guvensen A (2014) Halophytes in the East Mediterranean-their medicinal and other economical values. Sabkha ecosystems: volume IV: cash crop halophyte and biodiversity conservation tasks for vegetation science, vol 47. Springer, Dordrecht, pp 247–272

    Google Scholar 

  • Ozturk M, Altay V, AltundaÄŸ E, Gucel S (2016) Chapter 18: Halophytic plant diversity of unique habitats in Turkey: salt mine caves of Çankırı and IÄŸdır. In: Khan MA, Ozturk M, Gul B, Ahmed MZ (eds) Halophytes for food security in dry lands. Elsevier. https://doi.org/10.1016/B978-0-12-801854-5.00018-2

    Chapter  Google Scholar 

  • Ozturk M, Altay V, Gucel S, AltundaÄŸ E (2017a) Chapter 5: Plant diversity of the drylands in Southeast Anatolia-Turkey: role in human health and food security. In: Ansari AA, Gill SS (eds) Plant biodiversity: monitoring, assessment and conservation. CABI UK, pp 83–124

    Google Scholar 

  • Ozturk M, Altay V, Gonenç TM (2017b) Chapter 24: Herbal from high mountains in the East Mediterranean. In: Bhojraj S et al (eds) Drug discovery from herbs-approaches and applications. NAM S & T Centre, DAYA Publishing House, New Delhi, pp 327–367

    Google Scholar 

  • Ozturk M, Altay V, Hakeem KR, Akçiçek E (2017c) Liquorice from botany to Phytochemistry. SpringerBriefs Plant Sci. https://doi.org/10.1007/978-3-319-74240-3

  • Ozturk M, Altay V, Latiff A et al (2018a) Chapter 9: A comparative analysis of the medicinal pteridophytes in Turkey, Pakistan, and Malaysia. In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1. Springer, pp 349–390

    Google Scholar 

  • Ozturk M, Altay V, Latiff A et al (2018b) Chapter 11: A comparative analysis of the medicinal plants used for diabetes mellitus in the traditional medicine in Turkey, Pakistan, and Malaysia. In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1. Springer, pp 409–461

    Google Scholar 

  • Ozturk M, Altay V, Latiff A et al (2018c) Chapter 16: Potential medicinal plants used in the hypertension in Turkey, Pakistan, and Malaysia. In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1. Springer, pp 595–618

    Google Scholar 

  • Ozturk M, Gökler I, Altay V (2018d) Chapter 8: Medicinal bryophytes distributed in Turkey. In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1, 2018, Springer, pp 323–348

    Google Scholar 

  • Ozturk M, AltundaÄŸ E, Ibadullayeva SJ et al (2018e) A comparative analysis of medicinal and aromatic plants used in the traditional medicine of IÄŸdır (Turkey), Nakhchivan (Azerbaijan), and Tabriz (Iran). Pak J Bot 50(1):337–343

    Google Scholar 

  • Ozturk M, Altay V, AltundaÄŸ E et al (2018f) Chapter 6: Herbals in IÄŸdır (Turkey), Nakhchivan (Azerbaijan), and Tabriz (Iran). In: Ozturk M, Hakeem KR (eds) Plant and human health, vol 1. Springer, Cham, pp 197–266

    Google Scholar 

  • Ozturk M, Altay V, Orçen N et al (2018g) Chapter 3: A little known and a little consumed natural resource: Salicornia. In: Ozturk M et al (eds) Global perspectives on underutilized crops. Springer, p 83–108

    Google Scholar 

  • Ozturk M, Egamberdieva D, Milica P (2020) Biodiversity and biomedicine – our future. Academic Press – Elsevier Inc., London

    Google Scholar 

  • Pleskanovskaya SA, Mamedova MA, Ashıralıyeva MA et al (2019) Chapter 2: Glycyrrhiza glabra (liquorice) in Turkmenistan – medicinal and biological aspects. In: Ozturk M, Hakeem KR (eds) Plant and human health, − pharmacology and therapeutic uses, vol 3. Springer, Cham, pp 23–35

    Google Scholar 

  • Pradhan PC, Saha S (2016) Anthocyanin profiling of Berberis lycium Royle berry and its bioactivity evaluation for its nutraceutical potential. J Food Sci Technol 53(2):1205–1213

    CAS  PubMed  Google Scholar 

  • Qureshi NA, Ali Z (2011) Climate change, biodiversity Pakistan’s scenario. J Anim Plant Sci 21(2 SI):358–363

    Google Scholar 

  • Rahimi Madiseh M, Heidarian E, Rafieian-Kopaei M (2014) Biochemical components of Berberis lycium fruit and its effects on lipid profile in diabetic rats. J Herbmed Pharmacol 3(1):15–19

    Google Scholar 

  • Rao RR, Husain T, Datt B, Garg A (1998) Revision of the family Berberidaceae of the Indian region: 2. Rheedia 8(2):109–143

    Google Scholar 

  • Rashmi A, Rajasekaran A, Pant J (2008) The genus Berberis Linn.: a review. Pharmacogn Rev 2(4):369–385

    Google Scholar 

  • Rojas M (2009) Treaty of Mexican traditional medicine. Historical basis, clinical and theory-therapeutic practice. Tlahui Edu AC, Mexico City

    Google Scholar 

  • Saeed N, Khan MR, Shabbir M (2012) Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L. BMC Complement Altern Med 12(1):221

    CAS  PubMed  PubMed Central  Google Scholar 

  • Singh M, Srivastava S, Rawat AKS (2009) Antimicrobial studies of stem of different Berberis species. Nat Prod Sci 15(2):60–65

    CAS  Google Scholar 

  • Sofowora A, Ogunbodede E, Onayade A (2013) The role and place of medicinal plants in the strategies for disease prevention. Afr J Tradit Complement Altern Med 10(5):210–229

    PubMed  PubMed Central  Google Scholar 

  • Sood P, Modgil R, Sood M (2013) Berberis lycium, a medicinal plant with immense value. Indian J Pharm Biol Res 1:27–37

    Google Scholar 

  • Srivastava SK, Rawat AKS, Mehrotra S (2004) Pharmacognostic evaluation of the root of Berberis asiatica. Pharm Biol 42:467–473

    CAS  Google Scholar 

  • Surveswaran S, Cai YZ, Corke H, Sun M (2007) Systematic evaluation of natural phenolic antioxidants from 133 Indian medicinal plants. Food Chem 102(3):938–953

    CAS  Google Scholar 

  • Tiwari UL, Adhikari BS, Rawat GS (2012) A checklist of Berberidaceae in Uttarakhand, Western Himalaya, India. Check List 8(4):610–616

    Google Scholar 

  • Umair M, Altaf M, Abbasi AM (2017) An ethnobotanical survey of indigenous medicinal plants in Hafizabad district, Punjab-Pakistan. PLoS One 12(6):e0177912

    PubMed  PubMed Central  Google Scholar 

  • Uniyal SK, Singh KN, Jamwal P, Lal B (2006) Traditional use of medicinal plants among the tribal communities of Chhota Bhangal, Western Himalaya. J Ethnobiol Ethnomed 2(1):14

    PubMed  PubMed Central  Google Scholar 

  • WHO (World Health Organization) (2007) WHO guidelines on good agricultural and collection practices (GACP) for medicinal plants, Geneva

    Google Scholar 

  • Wojtowich Z, Wrona W, Kis G et al (2004) Serum total cholesterol, triglyceride and high density lipoprotein (HDL) level in rabbit during the course of experimental diabetes. Ann Univ Mariae Curie Sklodowska 59:258–264

    Google Scholar 

  • YeÅŸilada E, Küpeli E (2002) Berberis crataegina DC. Root exhibits potent anti-inflammatory, analgesic and febrifuge effects in mice and rats. J Ethnopharmacol 79(2):237–248

    PubMed  Google Scholar 

  • Younessi-Hamzekhanlu M, Ozturk M, Altay V et al (2020) Ethnopharmacological study of medicinal plants from Khoy city of West Azerbaijan-Iran. Indian J Tradit Knowl 19(2):251–267

    Google Scholar 

  • Zabihullah Q, Rashid A, Akhtar N (2006) Ethnobotanical survey in kot Manzari Baba valley Malakand agency, Pakistan. Pak J Plant Sci 12(2):115–121

    Google Scholar 

  • Zaidi SH (1998) Existing indigenous medicinal plant resources of Pakistan and their prospects for utilization. Pak J 48:1–5

    Google Scholar 

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Authors and Affiliations

  1. Department of Biotechnology, University of Azad Jammu and Kashmir, Muzaffarabad, Pakistan

    Syeda Maria Fiaz Bukhari & Ghazanfar Ali

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  1. Syeda Maria Fiaz Bukhari
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  2. Ghazanfar Ali
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Editors and Affiliations

  1. Department of Botany and Center for Environmental Studies, Ege University, Izmir, Türkiye

    Münir Öztürk

  2. Department of Plant Sciences, Quaid-i-Azam University, Islamabad, Pakistan

    Shujaul Mulk Khan

  3. Biology Department, Hatay Mustafa Kemal University, Antakya-Hatay, Türkiye

    Volkan Altay

  4. Department of Geography, Balıkesir University, Istanbul, Türkiye

    Recep Efe

  5. Faculty of Biology, National University of Uzbekistan, Tashkent, Uzbekistan

    Dilfuza Egamberdieva

  6. Institute of Botany, Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

    Furkat O. Khassanov

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Bukhari, S.M.F., Ali, G. (2022). An Overview of Ethnobotany of Berberis lycium Royle in Pakistan. In: Öztürk, M., Khan, S.M., Altay, V., Efe, R., Egamberdieva, D., Khassanov, F.O. (eds) Biodiversity, Conservation and Sustainability in Asia. Springer, Cham. https://doi.org/10.1007/978-3-030-73943-0_51

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