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Fatigue and Pain Measurements in Systemic Lupus Erythematosus

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Outcome Measures and Metrics in Systemic Lupus Erythematosus

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Abstract

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease characterized by heterogeneous clinical manifestations involving multiple organ systems. Fatigue and pain are two of the most prevalent and debilitating health complaints that negatively impact the health-related quality of life of SLE patients. Yet both fatigue and pain are difficult to clinically quantify, and significant heterogeneity exists among clinical studies with the utilization of different instruments for measuring fatigue and pain in SLE. This chapter describes the content and measurement properties of the most commonly administered instruments for evaluating fatigue and pain as well as reviews the disease-specific and patient-reported factors associated with fatigue and pain in the context of SLE disease.

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Authors and Affiliations

  1. University of Toronto, Division of Rheumatology, Department of Medicine, Toronto, ON, Canada

    Prabjit Ajrawat

  2. Division of Immunology & Rheumatology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA, USA

    Vibeke Strand

  3. McMaster University, Division of Rheumatology, Department of Medicine, Hamilton, ON, Canada

    Mark Matsos

  4. SDG, LLC, Cambridge, MA, USA

    Lee S. Simon

  5. Centre for Prognosis in Rheumatic Disease, Toronto Lupus Clinic, Division of Rheumatology, Department of Medicine, Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

    Zahi Touma

Authors
  1. Prabjit Ajrawat
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  2. Vibeke Strand
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  3. Mark Matsos
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  4. Lee S. Simon
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  5. Zahi Touma
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Correspondence to Zahi Touma .

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  1. Medicine, University of Toronto, Toronto, ON, Canada

    Zahi Touma

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Ajrawat, P., Strand, V., Matsos, M., Simon, L.S., Touma, Z. (2021). Fatigue and Pain Measurements in Systemic Lupus Erythematosus. In: Touma, Z. (eds) Outcome Measures and Metrics in Systemic Lupus Erythematosus. Springer, Cham. https://doi.org/10.1007/978-3-030-73303-2_15

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  • DOI: https://doi.org/10.1007/978-3-030-73303-2_15

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