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Pathophysiology of Obesity and Diabetes

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Dietary Phytochemicals

Abstract

Obesity is characterized by excessive accumulation of fats in the adipose tissues. Accumulation of excess fat releases a large number of adipokines that can cause obesity and diabetes mellitus due to irregularity between demand and the production of insulin. Obesity affects many organs and influences the heart, liver, intestines, respiratory organs, endocrine, and reproductive functions. Polydipsia, polyuria, weight reduction, coronary illness, kidney injury, diabetic foot, and diabetic ketoacidosis are pathophysiological manifestations and complications of diabetes. Obesity and overweight also contribute to the immune system dysfunction due to increased secretion of pro-inflammatory cytokines which are also risk factors for many types of cancer.

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Authors and Affiliations

  1. University Institute of Diet & Nutrition Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore, Pakistan

    Tabussam Tufail, Aiman Ijaz, Sana Noreen, Syed Amir Gilani, Shahid Bashir, Muhammad Zia Shahid, Ammar Ahmad Khan & Anees Ahmed Khalil

  2. Institute of Home & Food Sciences, Government College University Faisalabad, Faisalabad, Pakistan

    Tabussam Tufail & Muhammad Umair Arshad

  3. National Institute of Food Science & Technology, University of Agriculture Faisalabad, Faisalabad, Pakistan

    Ahmad Din

  4. School of Natural and Applied Sciences, Kampala International University, Kampala, Uganda

    Chinaza Godswill Awuchi

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  1. Tabussam Tufail
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  2. Aiman Ijaz
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Correspondence to Tabussam Tufail .

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  1. Faculty Natural Science, Department of Biochemistry, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria

    Chukwuebuka Egbuna

  2. Department of Nutritional Sciences, Faculty of Science and Technology, Government College Women University, Faisalabad, Pakistan

    Sadia Hassan

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Tufail, T. et al. (2021). Pathophysiology of Obesity and Diabetes. In: Egbuna, C., Hassan, S. (eds) Dietary Phytochemicals. Springer, Cham. https://doi.org/10.1007/978-3-030-72999-8_2

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