Skip to main content

Insecticidal Activities of Different Extracts of Calotropis procera

  • Chapter
  • First Online:
New Frontiers in Environmental Toxicology

Abstract

Calotropis procera has an important biological role in controlling pests and disease-spreading vectors. A search for biopesticide is a novel approach for reducing the risk and persistence of chemical and synthetic pesticides. Different parts of plants such as leaves, bark, roots, flowers, seeds, etc. are extensively studied by numerous authors for insecticidal properties; however, the outcomes are not available in compiled form. Efforts are done to compile the research done on its insecticidal properties in the past 20 years. The available data has been classified based on target insect taxonomical orders, plant part with details of different fractions of extract, their activity, insecticidal activity, dosage, and extent of lethality. Preliminary data on larvicidal, insecticidal, adulticidal, and LC50 were retrieved along with plant parts, solvent/solvent fraction detail, and insect details (taxonomical order, larva/adult, and stage of larva). Later the data was classified for each plant part extracted in each solvent/fraction with taxonomical order of insect, the dosage used, the lethality of the dosage, and author details.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abdalla, M., Elimam, K. H., Elmalik, F. S. Ali 2009. Efficacy of leaves extract of Calotropis procera Ait.(Asclepiadaceae) in controlling Anopheles arabiensis and Culex quinquefasciatus mosquitoes. Saudi J. Bio. Sci 2(16), 95-100.

    Google Scholar 

  • Alam, P., Ali, M. 2009. Phytochemical investigation of Calotropis procera Ait roots. Indian Journal of chemistry Vol 48 B, pp. 443–446

    Google Scholar 

  • Al-Doghairi, M. A., El Hag, E. 2003. Effect of several biopesticides on alfalfa weevil larvae, Hypera brunneipennis (Boheman). Pak J Biol Sci, 6(8), 777-781.

    Article  Google Scholar 

  • Arya, S., Kumar, V. L. 2005. Antiinflammatory efficacy of extracts of latex of Calotropis procera against different mediators of inflammation. Mediators of inflammation 2005 (4), 228-232.

    Article  Google Scholar 

  • Azmathullah, N. M. (2011). Phytochemical screening of Calotropis procera flower extracts and their bio-control potential on Culex sp. mosquito larvae and pupae. International Journal of Pharmaceutical & Biological Archive 2(6).

    Google Scholar 

  • Bakavathippan, G. A., Baskaran, S., Parvej, M., Jeyaparvathi, S. (2012). Effect of Calotropis procera leaf extract on Spodoptera litura (Fab.). J. Biopesticides 5:135.

    Google Scholar 

  • Bansal, S. K., Singh, K. V., Sharma, S., Sherwani, M. R. K. 2012. Laboratory observations on the larvicidal efficacy of three plant species against mosquito vectors of malaria, dengue/dengue hemorrhagic fever (DF/DHF) and lymphatic filariasis in the semi-arid desert. Journal of environmental biology 33(3), 617.

    CAS  Google Scholar 

  • Begum, N., Sharma, B., Pandey, R. S. 2013. Calotropis procera and Annona squamosa: potential alternatives to chemical pesticides. British Journal of Applied Science & Technology 3(2), 254.

    Article  Google Scholar 

  • Carlier, P. R., Anderson, T. D., Wong, D. M., Hsu, D. C., Hartsel, J., Ma, M., Bloomquist, J. R. 2008. Towards a species-selective acetylcholinesterase inhibitor to control the mosquito vector of malaria, Anopheles gambiae. Chemico-biological interactions 175(1–3), 368–375.

    Article  CAS  Google Scholar 

  • Chatterjee A., Pakarashi S. C. (1995). The treatise of Indian medicinal plants. (Publications and Information Directorate, CSIR, New Delhi) Vol. 4 130

    Google Scholar 

  • Chauhan A., Ranjan A. and Jindal, T (2016) Insecticidal Activity of Methanolic Extract of Calotropis procera against Callosobruchus maculatus using Moong Seeds (Vigna radiata) Journal of Biomedical and Pharmaceutical Research 5(6) 75–82.

    Google Scholar 

  • Chauhan A., Ranjan A., Jindal T. (2018) Biological Control Agents for Sustainable Agriculture, Safe Water and Soil Health. In: Jindal T. (eds) Paradigms in Pollution Prevention. Springer Briefs in Environmental Science. Springer, Cham https://doi.org/10.1007/978-3-319-58415-7_6

    Chapter  Google Scholar 

  • Cheng, S. S., Liu, J. Y., Huang, C. G., Hsui, Y. R., Chen, W. J., Chang, S. T. 2009. Insecticidal activities of leaf essential oils from Cinnamomum osmophloeum against three mosquito species. Bioresource Technology 100(1), 457–464.

    Article  CAS  Google Scholar 

  • Cheung, H. A., Chiu, F. C., Watson, T. R., Wells, R. J. 1983. Cardenolide glycosides of the Asclepiadaceae. New glycosides from Asclepias fruticosa and the stereochemistry of uscharin, voruscharin and calotoxin. Journal of the Chemical Society, Perkin Transactions 1 2827–2835.

    Article  Google Scholar 

  • Choedon, T., Mathan, G., Arya, S., Kumar, V. L., Kumar, V. 2006. Anticancer and cytotoxic properties of the latex of Calotropis procera in a transgenic mouse model of hepatocellular carcinoma. World Journal of Gastroenterology: WJG 12(16), 2517.

    Article  Google Scholar 

  • Conti, B., Canale, A., Bertoli, A., Gozzini, F., Pistelli, L. 2010. Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae). Parasitology research 107(6), 1455–1461.

    Article  Google Scholar 

  • De Morais, S. M., Facundo, V. A., Bertini, L. M., Cavalcanti, E. S. B., dos Anjos Júnior, J. F., Ferreira, S. A., … & de Souza Neto, M. A. 2007. Chemical composition and larvicidal activity of essential oils from Piper species. Biochemical Systematics and Ecology 35(10), 670–675.

    Google Scholar 

  • Esmaeily, S., Samih, M. A., Zarabi, M., Jafarbeigi, F. 2012. Comparative Study of Insecticides and Calotropis procera Extract on Biological Parameters of Bemisia tabaci (Genn.). Annals of Plant Protection Sciences 20(1), 14–18.

    Google Scholar 

  • Fournier, D., Mutero, A. 1994. Modification of acetylcholinesterase as a mechanism of resistance to insecticides. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 108(1), 19–31

    Google Scholar 

  • Giordani, R., Benyahia, S., Teissère, M., Noat, G. 1992. Purification and properties of N-acetyl-β--glucosaminidase from Hevea brasiliensis latex. Plant Science 84(1), 25–34.

    Article  CAS  Google Scholar 

  • Gogoi, H., Bora, D. 2012. Bio-efficacy Potential of Some Ethnically Important Plants Against Nymphula depunctalis Guenée (Lepidoptera: Pyralidae) Larvae with Special Reference to Calotropis procera and Zanthoxylum nitidum. National Academy Science Letters 35(3), 169–175.

    Article  Google Scholar 

  • Grundy, D. L., Still, C. C. 1985. Inhibition of acetylcholinesterases by pulegone-1, 2-epoxide. Pesticide biochemistry and physiology 23(3), 383–388.

    Article  CAS  Google Scholar 

  • Hanna AG., Shalaby NMM., Morsy NAM., Simon A., Tóth G., Malik S., Duddeck H. 2002; Structure of a calotropagenin-derived artifact from Calotropis procera. Magnetic Resonance in Chemistry; 40:599–602

    Article  CAS  Google Scholar 

  • Hesse and Ludwing, G. 1960. African arrow poisons XIV. Voruscharine, a second sulfur-containing heart poison from Calotropis procera L. Justus Lieb. Ann Chem 632, 158–171.

    Article  Google Scholar 

  • Irannejad, M. K., Samih, M. A., Jahromi, K. T., Alizadeh, A. 2012. The side Effects of Several Pesticides and Plant Extracts on Biological Parameters of Green Lacewing Chrysoperla carnea (Neuroptera: Chrysopidae) After Treating Eggs and 3rd Instar Under Laboratory Conditions. Plant Protection (Scientific Journal of Agriculture) 35, 3.

    Google Scholar 

  • Islam, M. S., Aktar, M. J. 2013. Larvicidal efficacies of some plant extracts and their synergistic effects with cypermethrin on the life-history traits of Musca domestica L. Int. J. Innov. Biosci 3, 92–103.

    Google Scholar 

  • K.K. Mueen Ahmed, A.C. Rana, V.K. Dixit (2005). Calotropis species (Asclepediaceae) a comprehensive review Pharmacognosy Magazine, 1 (2), pp. 48–52

    Google Scholar 

  • Kamalam, J. N., Anburaj, J., Sundaravadivelan, C., Kumar, P., Kuberan, T., Dhasarathan, P. 2013. Effect of pyrotechnic chemicals in digestive tract microflora and proximate composition in fish Oreochromis mossambicus. Adv. Appl. Sci. Res 4(1), 188–194.

    Google Scholar 

  • Khan, A. Q., Malik, A. 1989. A steroid from Calotropis procera. Phytochemistry, 28(10), 2859–2861

    Article  CAS  Google Scholar 

  • Khanzada, S. K., Shaikh, W., Kazi, T. G., Sofia, S., Kabir, A., Usmanghani, K., Kandhro, A. A. 2008. Analysis of fatty acid, elemental and total protein of Calotropis procera medicinal plant from Sindh, Pakistan. Pak J Bot 40(5), 1913–1921.

    CAS  Google Scholar 

  • Knio, K. M., Usta, J., Dagher, S., Zournajian, H., Kreydiyyeh, S. 2008. Larvicidal activity of essential oils extracted from commonly used herbs in Lebanon against the seaside mosquito, Ochlerotatus caspius. Bioresource technology 99(4), 763–768.

    Article  CAS  Google Scholar 

  • Konno, K. 2011. Plant latex and other exudates as plant defense systems: roles of various defense chemicals and proteins contained therein. Phytochemistry 72(13), 1510–1530

    Article  CAS  Google Scholar 

  • Matthew O. A. Adaramoy O.A. 2014. Anti-Acetylcholinesterase Activity of Methanol extract of Calotropis Procera Leaves. International Journal of Science and Research 3(11), 724–727.

    Google Scholar 

  • Meena, A. K., Yadav, A. K., Niranjan, U. S., Singh, B., Nagariya, A. K., Sharma, K., Rao, M. M. 2015. A review on Calotropis procera Linn and its ethnobotany, phytochemical, pharmacological profile. Drug Invention Today 185–190.

    Google Scholar 

  • Mohamed, N. H., Liu, M., Abdel-Mageed, W. M., Alwahibi, L. H., Dai, H., Ismail, M. A., Shoreit, A. A. 2015. Cytotoxic cardenolides from the latex of Calotropis procera. Bioorganic & medicinal chemistry letters, 25(20), 4615–4620.

    Article  CAS  Google Scholar 

  • Oloumi, H. 2014. Phytochemistry and ethno-pharmaceutics of Calotropis procera. Ethno-Pharmaceutical Products 1(2), 1–8.

    Google Scholar 

  • Parihar, G., Balekar, N. 2016. Calotropis procera: A phytochemical and pharmacological review. Thai Journal of Pharmaceutical Sciences 40(3).

    Google Scholar 

  • Pavela, R. 2015. Essential oils for the development of eco-friendly mosquito larvicides: a review. Industrial Crops and Products 76, 174–187.

    Article  CAS  Google Scholar 

  • Perwez, A., Mohammad, A. 2009. Phytochemical investigation of Calotropis procera roots. Indian Journal of chemistry B 48, 443–446.

    Google Scholar 

  • Quazi, S., Mathur, K., Arora, S., Wing, P. 2013a. Calotropis procera: An overview of its phytochemistry and pharmacology. Indian J. Drugs 1(2), 63–69.

    Google Scholar 

  • Quazi, S., Mathur, K., Arora, S., Wing, P. 2013b. Calotropis procera: An overview of its phytochemistry and pharmacology. Indian J. Drugs 1(2), 63–69.

    Google Scholar 

  • Qureshi, A. A., Patil, T., Swamy, A. H. M., Gouda, V. A., Setty, R. S. 2007. Hepatoprotective and antioxidant activities of flowers of Calotropis procera (Ait) R. Br. in CCl4 induced hepatic damage. Indian journal of experimental biology 45, 304–310.

    Google Scholar 

  • Rahman, M. A., Wilcock, C. C. 1991. A taxonomic revision of Calotropis (Asclepiadaceae). Nordic Journal of Botany 11(3), 301–308.

    Article  Google Scholar 

  • Rahman, M. A., Wilcock, C. C. 1992.Diversity of life-form and distribution of the Asclepiadaceae in south-west Asia and the Indian subcontinent. Journal of biogeography 51–58.

    Google Scholar 

  • Ramos, M. V., Bandeira, G. D. P., Freitas, C. D. T. D., Nogueira, N. A. P., Alencar, N. M. N., Sousa, P. A. S. D., Carvalho, A. F. U. 2006. Latex constituents from Calotropis procera (R. Br.) display toxicity upon egg hatching and larvae of Aedes aegypti (Linn.). Memórias do Instituto Oswaldo Cruz 101(5), 503–510.

    Article  Google Scholar 

  • Ranjan A., Chauhan, A., & Jindal, T. (2018). In-silico and in-vitro evaluation of human acetylcholinesterase inhibition by organophosphates. Environmental toxicology and pharmacology, 57, 131–140.

    Article  CAS  Google Scholar 

  • Rohit M., Taranalli Ashok., Rasal Vijaykumar., Kamlesh Kashniyal, 2016. Molecular Docking Study of Cassia tora, Brassica campestris and Calotropis procera as Acetylcholinesterase Inhibitor 50(1) 116–122.

    CAS  Google Scholar 

  • Saber, A. H., Maharan, G. H., Rizkallah, M. M., Ste Saber, A. H. 1969. Sterols and pentacyclic triterpenes of Calotropis procera. Bull Fac Pharm Cairo Univ 7(1).

    Google Scholar 

  • Sehgal, R., Roy, S., Kumar, V. L. 2006. Evaluation of cytotoxic potential of latex of Calotropis procera and Podophyllotoxin in Allum cepa root model. Biocell 30(1), 9–13.

    Article  CAS  Google Scholar 

  • Shahi, N., Hanati-Bojo, A., Iranshahi, M., Vatandoost, H., Mansour, A. 2010. Larvicidal efficacy of latex and extract of Calotropis procera against Culex quinquefasciatus and Anopheles stephensi (Diptera: Culicidae). Vector Borne Diseases 47, 185–188.

    CAS  Google Scholar 

  • Sharma AK, Kharb R, Kaur R (2011) Pharmacognostical aspects of Calotropis procera (Ait.) R. Br. Int J Pharm Bio Sci 2(3):480–488

    Google Scholar 

  • Shobowale, O. O., Ogbulie, N. J., Itoandon, E. E., Oresegun, M. O., Olatope, S. O. A. 2013. Phytochemical and antimicrobial evaluation of aqueous and organic extracts of Calotropis procera ait leaf and latex. Nigerian Food Journal 31(1), 77–82.

    Article  Google Scholar 

  • Singh, A. P., Pathak, D., Verma, N. K., Panda, P. 2015. Journal of Chemical and Pharmaceutical Research 2015, 7 (5): 1366–1369.

    Google Scholar 

  • Singh, K. P., Arya, S. 2011. Phytochemical profile and evaluation of insecticidal efficacy of Calotropis procera against defoliators. Journal of Medicinal Plants Research 5(31), 6738–6743.

    Google Scholar 

  • Singh, R. K., Mittal, P. K., Dhiman, R. C. 2005. Laboratory study on larvicidal properties of leaf extract of Calotropis procera (Family-Asclepiadaceae) against mosquito larvae. Journal of Communicable Diseases 37(2), 109.

    CAS  Google Scholar 

  • Sweidan, N. I., Abu Zarga, M. H. 2015. Two novel cardenolides from Calotropis procera. Journal of Asian natural products research 17(9), 900–907.

    Article  CAS  Google Scholar 

  • Tezara, W., Colombo, R., Coronel, I., Marín, O. 2010. Water relations and photosynthetic capacity of two species of Calotropis in a tropical semi-arid ecosystem. Annals of botany 107(3), 397–405.

    Article  Google Scholar 

  • Upadhyay, R. 2014. Ethnomedicinal, pharmaceutical and pesticidal uses of Calotropis procera (Aiton)(Family: Asclepiadaceae). International Journal of Green Pharmacy 8(3), 135.

    Article  CAS  Google Scholar 

  • Wang, J. C., Hinrichs, A. L., Stock, H., Budde, J., Allen, R., Bertelsen, S., Jones, K. 2004. Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Human molecular genetics 13(17), 1903–1911.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Abhishek Chauhan .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Kumar, D., Ranjan, A., Chauhan, A., Prakash, D., Jindal, T. (2022). Insecticidal Activities of Different Extracts of Calotropis procera. In: Jindal, T. (eds) New Frontiers in Environmental Toxicology. Springer, Cham. https://doi.org/10.1007/978-3-030-72173-2_7

Download citation

Publish with us

Policies and ethics