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Endoscopic Ultrasound-Guided Fiducial Marker Placement for Stereotactic Body Radiotherapy (SBRT) of Pancreatic Cancer

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Endoscopic Ultrasound Management of Pancreatic Lesions

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Abstract

The current standard of care for locally advanced pancreatic cancer (LAPC) is chemotherapy which provides patients with a median survival of 6–8 months. The addition of conventional external beam radiotherapy (EBRT) was previously associated with toxicity and is not routinely recommended. The development of stereotactic body radiotherapy (SBRT) potentially allows more selective delivery of radiation to the tumour. However, in order to deliver SBRT precisely, the placement of fiducial markers helps to compensate for tumour motion during respiration by tracking and accurately determining tumour boundaries. Although fiducials can be implanted percutaneously and laparoscopically, the minimally invasive endoscopic ultrasound (EUS)-guided approach has been the methods of choice. This chapter outlined the types, techniques, and related outcomes of EUS-guided fiducial implantation to assist the delivery of radiotherapy for LAPC.

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Author information

Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, Australia

    Jeevinesh Naidu, Vinh-An Phan & Nam Q. Nguyen

  2. School of Health and Medical Sciences, University of Adelaide, Adelaide, Australia

    Jeevinesh Naidu, Vinh-An Phan & Nam Q. Nguyen

Authors
  1. Jeevinesh Naidu
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  2. Vinh-An Phan
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  3. Nam Q. Nguyen
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Corresponding author

Correspondence to Nam Q. Nguyen .

Editor information

Editors and Affiliations

  1. Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

    Antonio Facciorusso

  2. Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy

    Nicola Muscatiello

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Naidu, J., Phan, VA., Nguyen, N.Q. (2021). Endoscopic Ultrasound-Guided Fiducial Marker Placement for Stereotactic Body Radiotherapy (SBRT) of Pancreatic Cancer. In: Facciorusso, A., Muscatiello, N. (eds) Endoscopic Ultrasound Management of Pancreatic Lesions. Springer, Cham. https://doi.org/10.1007/978-3-030-71937-1_13

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  • DOI: https://doi.org/10.1007/978-3-030-71937-1_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-71936-4

  • Online ISBN: 978-3-030-71937-1

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