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Non Invasive Ventilation in Asthma Exacerbation

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Teaching Pearls in Noninvasive Mechanical Ventilation
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Abstract

The use of non-invasive ventilation (NIV) in severe acute asthma is controversial. pH <7.25, PaCO2 >60 mmHg, altered mental status have been described as contraindications to NIV in acute asthma exacerbation. This case shows that in a patient who does not respond to oxygen therapy, NIV has been effectively used to treat hypoxemia and hypercapnia associated with asthma exacerbation.

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Abbreviations

%:

Percent sign

bpm:

Beats per minute

cmH2O:

Centimeter of water

COPD:

Chronic obstructive pulmonary disease

CRP:

C-reactive protein

ECG:

Electrocardiogram

FiO2:

Fraction of inspired oxygen

HCO3:

Bicarbonate

ICU:

Intensive care unit

IMV:

Invasive mechanical ventilation

L/min:

Liter per minute

mg/h:

Milligram per hour

μL:

Microliter

mL/kg:

Milliliters to kilograms

mmHg:

Millimeter of mercury

mmol/L:

Millimoles per liter

NC:

Nasal cannula

NIV:

Non-invasive ventilation

P/F:

Partial pressure of arterial oxygen/fraction of inspired oxygen

PaCO2:

Partial pressure of arterial carbon dioxide

PaO2:

Partial pressure of arterial oxygen

PEEP:

Positive end expiratory pressure

pH:

Potential of hydrogen

SpO2:

Peripheral capillary oxygen saturation

WBC:

White blood cell

References

  1. Global Initiative for Asthma. Global strategy for asthma management and prevention: GINA. 2018.

    Google Scholar 

  2. Lazarus SC. Clinical practice. Emergency treatment of asthma. N Engl J Med. 2010;363(8):755–64.

    Article  CAS  Google Scholar 

  3. National AE, Prevention P. Expert panel report 3 (EPR-3): guidelines for the diagnosis and management of asthma-summary report 2007. J Allergy Clin Immunol. 2007;120(5 Suppl):S94.

    Google Scholar 

  4. Soma T, Hino M, Kida K, et al. A prospective and randomized study for improvement of acute asthma by non-invasive positive pressure ventilation (NPPV). Intern Med. 2008;47:493–501.

    Article  Google Scholar 

  5. Korang SK, Feinberg J, Wetterslev J, Jakobsen JC. Non-invasive positive pressure ventilation for acute asthma in children. Cochrane Database Syst Rev. 2016;9:CD012067.

    PubMed  Google Scholar 

  6. Navanandan N, Federico M, Mistry RD. Positive expiratory pressure for the treatment of acute asthma exacerbations: a randomized controlled trial. J Pediatr. 2017;185:149–54.

    Article  Google Scholar 

  7. Sun LH, Tan Y, Zhao HD, et al. Effects of noninvasive positive pressure ventilation on respiratory muscle fatigue in patients with acute exacerbations of chronic obstructive pulmonary disease: a randomized controlled trial. Zhonghua Nei Ke Za Zhi. 2007;46:992–5.

    PubMed  Google Scholar 

  8. Fernández MM, Villara A, Blanch L, et al. Noninvasive mechanical ventilation in status asthmaticus. Intensive Care Med. 2001;27(3):486–92.

    Article  Google Scholar 

  9. Gupta D, Nath A, Agarwal R, Behera D. A prospective randomized controlled trial on the efficacy of noninvasive ventilation in severe acute asthma. Respir Care. 2010;55(5):536–43.

    PubMed  Google Scholar 

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Correspondence to Burhan Sami Kalın .

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Kalın, B.S. (2022). Non Invasive Ventilation in Asthma Exacerbation. In: Esquinas, A.M. (eds) Teaching Pearls in Noninvasive Mechanical Ventilation. Springer, Cham. https://doi.org/10.1007/978-3-030-71298-3_32

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  • DOI: https://doi.org/10.1007/978-3-030-71298-3_32

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-71297-6

  • Online ISBN: 978-3-030-71298-3

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