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Urethral Bulking Agents

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Female Genitourinary and Pelvic Floor Reconstruction

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Abstract

Urethral bulking agents (UBA) has been used for decades to treat stress urinary incontinence (SUI). After being first described in the 1930s, several agents have been introduced to the market with varying profiles of safety, durability, and efficacy. Currently available agents include polyacrylamide hydrogel (Bulkamid®), calcium hydroxyl apatite (Coaptite®), carbon-coated zirconium (Durasphere®), polydimethylsiloxane elastomer (Macroplastique®), and PDMS-U (Urolastic®). Considered safe and minimally invasive procedures, UBA benefit from a renewed interest from patients and practitioners, regarding the growing controversies surrounding the use of mid-urethral synthetic slings. After describing the mechanisms of action and injection techniques, this chapter looks at currently available UAB and their own safety and efficacy profile based on the most relevant data found in the literature.

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Author information

Authors and Affiliations

  1. Department of Urology, McGill University, Jewish General Hospital, Montreal, QC, Canada

    Quentin Alimi, Béatrice Bouchard & Jacques Corcos

Authors
  1. Quentin Alimi
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  2. Béatrice Bouchard
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  3. Jacques Corcos
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Corresponding author

Correspondence to Quentin Alimi .

Editor information

Editors and Affiliations

  1. University of Lisbon, Lisbon, Portugal

    Francisco E. Martins

  2. University of Oslo, Oslo, Norway

    Henriette Veiby Holm

  3. Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Jaspreet Sandhu

  4. Eastern Virginia Medical School, Norfolk, VA, USA

    Kurt A McCammon

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Alimi, Q., Bouchard, B., Corcos, J. (2022). Urethral Bulking Agents. In: Martins, F.E., Holm, H.V., Sandhu, J., McCammon, K.A. (eds) Female Genitourinary and Pelvic Floor Reconstruction. Springer, Cham. https://doi.org/10.1007/978-3-030-71112-2_25-1

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  • DOI: https://doi.org/10.1007/978-3-030-71112-2_25-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-71112-2

  • Online ISBN: 978-3-030-71112-2

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