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Cyclitols – Determination in Food and Bioactivity in the Human Organism

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Analytical Methods in the Determination of Bioactive Compounds and Elements in Food

Part of the book series: Food Bioactive Ingredients ((FBC))

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Abstract

Cyclitols are high polarity polyols, belonging to secondary metabolites, which are easily isolable from plant material. These compounds are biosynthetically derived from glucose, and occur in all living cells. They form a group of biologically active compounds and participate in many cellular processes such as: membrane biogenesis, signal transduction, ion channel physiology, osmoregulation, antioxidation, and others. The methods for the separation and determination of cyclitols include: preliminary sample preparation (drying, grinding, freezing, homogenization), sample extraction (optional: maceration, Soxhlet, ASE, MAE, SFE, UAE), isolation and purification (LLE, SPE, and others), analysis (GC-MS, HPLC, MALDI), and interpretation (identification, quantification, statistical analysis). Some other additional steps may be required, which are specific for the method chosen for the analysis. For example GC-MS analysis requires a derivatization step, while MALDI involves a laborious procedure for sample preparation. Cyclitols shows several health-promoting and therapeutic properties as follows: improving lipid profile in decreasing of serum triglycerides and total cholesterol, as well as having an insulin-mimetic effect. The beneficial properties of cyclitols are that they can be used for therapeutic purposes, particularly in neutralization of the results of chronic inflammation, which leads to increased risk of developing such metabolic disorders as diabetes, hypertension, atherosclerosis, etc. A notable factor is also good tolerance of cyclitols and their low toxicity, due to which they can be successfully used in treating pregnant women and children. Many benefits of cyclitols properties offer the possibility that these polyols may be candidates for discovery of novel drugs, food supplements and they can be used as well in cosmetic industry.

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Authors and Affiliations

  1. Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Torun, Poland

    Magdalena Ligor, Hossam Al-Suod & Bogusław Buszewski

  2. Interdisciplinary Centre of Modern Technologies, Nicolaus Copernicus University, Torun, Poland

    Ileana-Andreea Rațiu, Hossam Al-Suod & Bogusław Buszewski

  3. “Raluca Ripan” Institute for Research in Chemistry, Babes-Bolyai University, Cluj-Napoca, Romania

    Ileana-Andreea Rațiu

  4. Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology, The University of Warmia and Mazury, Olsztyn, Poland

    Agnieszka Owczarczyk-Saczonek

  5. Department of Plant Physiology and Biotechnology, Faculty of Biology and Biotechnology, University of Warmia and Mazury, Olsztyn, Poland

    Lesław Lahuta & Ryszard Górecki

Authors
  1. Magdalena Ligor
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  2. Ileana-Andreea Rațiu
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  3. Hossam Al-Suod
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  4. Agnieszka Owczarczyk-Saczonek
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  5. Lesław Lahuta
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  6. Ryszard Górecki
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  7. Bogusław Buszewski
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Corresponding author

Correspondence to Magdalena Ligor .

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Editors and Affiliations

  1. Institute of Chemistry and Technical Electrochemistry, Poznan University of Technology, Poznań, Poland

    Magdalena Jeszka-Skowron

  2. Institute of Chemistry and Technical Electrochemistry, Poznan University of Technology, Poznań, Poland

    Agnieszka Zgoła-Grześkowiak

  3. Institute of Chemistry and Technical Electrochemistry, Poznan University of Technology, Poznań, Poland

    Tomasz Grześkowiak

  4. Vegetable R & D Department, Bayer Crop Science division, Gauribidanur, Karnataka, India

    Akula Ramakrishna

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Ligor, M. et al. (2021). Cyclitols – Determination in Food and Bioactivity in the Human Organism. In: Jeszka-Skowron, M., Zgoła-Grześkowiak, A., Grześkowiak, T., Ramakrishna, A. (eds) Analytical Methods in the Determination of Bioactive Compounds and Elements in Food. Food Bioactive Ingredients. Springer, Cham. https://doi.org/10.1007/978-3-030-61879-7_7

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