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Analysis of Population Structure

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Human Population Genomics

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Abstract

For humans, like any sexually reproducing diploid organism, mating may be random in the sense that individuals are equally likely to mate and produce offspring. Such a view of a population has been important in population genetics as a basis for modeling and analysis. Population structure denotes deviation from this panmixia, regardless of the cause. In this chapter, we will briefly discuss random mating, populations, population structure, and various methods and practices to infer population structure among individuals from empirical genome-wide data.

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Authors and Affiliations

  1. Human Evolution, Department of Organismal Biology, Uppsala University, Uppsala, Sweden

    Per Sjödin, Lucie Gattepaille, Pontus Skoglund, Carina Schlebusch & Mattias Jakobsson

  2. The Francis Crick Institute, London, UK

    Pontus Skoglund

  3. Science for Life Laboratory, Uppsala University, Uppsala, Sweden

    Carina Schlebusch & Mattias Jakobsson

  4. Department of Anthropology and Development Studies, Centre for Anthropological Research, University of Johannesburg, Auckland Park, South Africa

    Carina Schlebusch & Mattias Jakobsson

Authors
  1. Per Sjödin
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  2. Lucie Gattepaille
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  3. Pontus Skoglund
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  4. Carina Schlebusch
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  5. Mattias Jakobsson
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Correspondence to Mattias Jakobsson .

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Editors and Affiliations

  1. Ecology and Evolutionary Biology, University of California, Los Angeles, CA, USA

    Kirk E. Lohmueller

  2. Integrative Biology, University of California, Berkeley, CA, USA

    Rasmus Nielsen

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Sjödin, P., Gattepaille, L., Skoglund, P., Schlebusch, C., Jakobsson, M. (2021). Analysis of Population Structure. In: Lohmueller, K.E., Nielsen, R. (eds) Human Population Genomics. Springer, Cham. https://doi.org/10.1007/978-3-030-61646-5_3

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