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Colon Cancer

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Lower Gastrointestinal Tract Surgery

Part of the book series: Springer Surgery Atlas Series ((SPRISURGERY))

Abstract

Over the last 25 years, enormous progress has been achieved to improve the treatment of rectal cancer due to standardisation of surgery (total mesorectal excision, “the holy plane,” nerve preservation) [1, 2] and the introduction of radiotherapy to reduce local recurrence [3, 4]. However, surgical treatment of colon cancer did not attract similar interest. Surgery for colon cancer was assumed to be easier to perform, ignoring the increasing gap of survival between rectal and colon cancer, which had reversed since the early 1990s [5]. Some surgeons, however, had already reported much higher survival figures compared with the literature at that time [6, 7].

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References

  1. Heald RJ. The ‘Holy Plane’ of rectal surgery. J R Soc Med. 1988;81:503–8.

    Article  CAS  Google Scholar 

  2. Havenga K, DeRuiter MC, Enker WE, Welvaart K. Anatomical basis of autonomic nerve-preserving total mesorectal excision for rectal cancer. Br J Surg. 1996;83:384–8.

    Article  CAS  Google Scholar 

  3. Påhlman L, Glimelius B. Preoperative or postoperative radiotherapy in rectal and rectosigmoid carcinoma–report from a randomized trial. Ann Surg. 1990;211:187–95.

    Article  Google Scholar 

  4. Sauer R, Becker H, Hohenberger W, Rödel C, Wittekind C, Fietkau R, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 2004;351:1731–40.

    Article  CAS  Google Scholar 

  5. Birgisson H, Talbeck M, Gunnarsson U, Påhlman L, Glimelius B. Improved survival in cancer of the colon and rectum in Sweden. Eur J Surg Oncol. 2005;31(8):845–53.

    Article  CAS  Google Scholar 

  6. Enker WE, Laffer UT, Block GE. Enhanced survival of patients with colon and rectal cancer is based upon wide anatomic resection. Ann Surg. 1979;190:350–60.

    Article  CAS  Google Scholar 

  7. Hohenberger W, Reingruber B, Merkel S. Surgery for colon cancer. Scand J Surg. 2003;92:45–52.

    Article  CAS  Google Scholar 

  8. Hohenberger W, Weber K, Matzel K, Papadopoulos T, Merkel S. Standardized surgery for colonic cancer: complete mesocolic excision and central ligation—technical notes and outcome. Colorectal Dis. 2009;11:354–64.

    Article  CAS  Google Scholar 

  9. West NP, Hohenberger W, Weber K, Perrakis A, Finan PJ, Quirke P. Complete mesocolic excision with central vascular ligation produces an oncologically superior specimen compared with standard surgery for carcinoma of the colon. J Clin Oncol. 2010;28:272–8.

    Article  Google Scholar 

  10. Le Voyer TE, Sigurdson ER, Hanlon AL, Mayer RJ, Macdonald JS, Catalano PJ, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol. 2003;21(15):2912–9.

    Article  Google Scholar 

  11. Rosenberg R, Friederichs J, Schuster T, Gertler R, Maak M, Becker K, et al. Prognosis of patients with colorectal cancer is associated with lymph node ratio. A single-center analysis of 3026 patients over a 25-year time period. Ann Surg. 2008;248:968–78.

    Article  Google Scholar 

  12. Kobayashi H, West NP, Takahashi K, Perrakis A, Weber K, Hohenberger W, et al. Quality of surgery for stage III colon cancer: comparison between England, Germany and Japan. Ann Surg Oncol. 2014;21:398–404.

    Article  Google Scholar 

  13. Søndenaa K, Quirke P, Hohenberger W, Sugihara K, Kobayashi H, Kessler H, et al. The rationale behind complete mesocolic excision (CME) and a central vascular ligation for colon cancer in open and laparoscopic surgery: proceedings of a consensus conference. Int J Colorectal Dis. 2014;29:419–28.

    Article  Google Scholar 

  14. Perrakis A, Weber K, Merkel S, Matzel K, Agaimy A, Gebhart C, et al. Lymph node metastasis of carcinomas of transverse colon including flexures. Consideration of the extramesocolic lymph node stations. Int J Colorectal Dis. 2014;29:1223–9.

    Article  Google Scholar 

Suggested Reading

  • Hohenberger W, Mohr VD, Goehl J. Anastomosis techniques in the lower gastrointestinal tract. Chirurg. 1993;64:690–700.

    CAS  PubMed  Google Scholar 

  • Quirke P, Steele R, Monson J, Grieve R, Khanna S, Couture J, et al. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet. 2009;373:821–8.

    Article  Google Scholar 

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Correspondence to Klaus Weber .

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Hohenberger, W., Weber, K. (2021). Colon Cancer. In: Hohenberger, W., Parker, M. (eds) Lower Gastrointestinal Tract Surgery. Springer Surgery Atlas Series. Springer, Cham. https://doi.org/10.1007/978-3-030-60827-9_7

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  • DOI: https://doi.org/10.1007/978-3-030-60827-9_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-60826-2

  • Online ISBN: 978-3-030-60827-9

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