Skip to main content
SpringerLink
Log in

Congenital Hemangioma

  • Chapter
  • First Online:
Soft Tissue Tumors

Abstract

Congenital hemangioma is a benign tumor of vascular origin.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 129.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    GLUT1: this gene (also known as SLC2A1, solute carrier family 2 member 1) encodes a major glucose transporter in the mammalian blood-brain barrier.

  2. 2.

    WT1: the Wilms tumor 1 gene encodes a transcription factor with an essential role in the normal development of the urogenital system. It is mutated in a small subset of patients with Wilms tumor.

  3. 3.

    GNAQ: the G protein subunit alpha Q gene encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospholipase C-beta.

  4. 4.

    GNA11: the G protein subunit alpha 11 gene encodes a protein belonging to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of three units: alpha, beta, and gamma. This gene encodes one of the alpha subunits (subunit alpha 11).

Suggested Readings

  • Ayturk (2016) Somatic activating mutations in GNAQ and GNA11 are associated with congenital hemangioma. Am J Hum Genet 98(4):789–795

    Article  CAS  Google Scholar 

  • Johnson (2018) Vascular tumors in infants: case report and review of clinical, histopathologic, and immunohistochemical characteristics of infantile hemangioma, pyogenic granuloma, noninvoluting congenital hemangioma, tufted angioma, and kaposiform hemangioendothelioma. Am J Dermatopathol 40(4):231–239

    Article  Google Scholar 

  • Wildgruber (2019) Vascular tumors in infants and adolescents. Insights Imaging 10(1):30

    Article  Google Scholar 

  • Yang (2015) Clinical characteristics and treatment options of infantile vascular anomalies. Medicine (Baltimore) 94(40):e1717

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery Oncology and Gastroenterology, University of Padova, Padova, Italy

    Simone Mocellin

  2. Melanoma and Soft Tissue Sarcoma Unit, Istituto Oncologico Veneto (IOV-IRCCS) of Padova, Padova, Italy

    Simone Mocellin

Authors
  1. Simone Mocellin
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Simone Mocellin .

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Mocellin, S. (2021). Congenital Hemangioma. In: Soft Tissue Tumors . Springer, Cham. https://doi.org/10.1007/978-3-030-58710-9_55

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-58710-9_55

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-58709-3

  • Online ISBN: 978-3-030-58710-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation