Abstract
Predetermination, formation and maintenance of the primary morphogenetic gradient (bicoid, bcd, gradient) of the early Drosophila embryo involves many interrelated processes. Here we focus on a systems biological analysis of the bcd mRNA redistribution in an early embryo. The results of the quantitative analysis of experimental data, together with the results of their dynamic modeling, substantiate the role of active transport in the redistribution of the bcd mRNA.
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Acknowledgement
This work was supported by the Russian Foundation for Basic Research (project no. 20-04-01015).
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Myasnikova, E.M., Samuta, V.Y., Spirov, A.V. (2020). Quantitative Analysis of the Dynamics of Maternal Gradients in the Early Drosophila Embryo. In: Cai, Z., Mandoiu, I., Narasimhan, G., Skums, P., Guo, X. (eds) Bioinformatics Research and Applications. ISBRA 2020. Lecture Notes in Computer Science(), vol 12304. Springer, Cham. https://doi.org/10.1007/978-3-030-57821-3_40
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DOI: https://doi.org/10.1007/978-3-030-57821-3_40
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