Abstract
Mixed urinary incontinence (MUI), according to ICS, is “the complaint of involuntary leakage associated with urgency, and also with effort, exertion, sneezing and coughing”. MUI is a common finding among female patients who report urinary incontinence (UI).
A pathologic mechanism that combines stress urinary incontinence (SUI) and OAB, therefore resulting in MUI, has been described by various authors as the “urethrogenic” or “urethrocentric” theory. According to the urethrogenic theory, the opening of the proximal urethra would also trigger a urethro-vesical reflex resulting in a bladder contraction and more severe urine leakage.
Conforming to the “urethrogenic” pathological model, the interruption of the urethro-vesical reflex can explain the effectiveness of SUI surgery also on OAB symptoms. Preventing the improper flow of urine through the proximal urethra under strain would interrupt the urethro-vesical reflex in patients with urethral incompetence. Therefore, the pathologic mechanism causing the dysfunction would be cured, resulting in the resolution of both the stress and the irritative symptoms.
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Soligo, M., Giammò, A. (2021). Overactive Bladder and Female Stress Urinary Incontinence. In: Balzarro, M., Li Marzi, V. (eds) Non-Neurogenic Bladder Dysfunctions. Urodynamics, Neurourology and Pelvic Floor Dysfunctions. Springer, Cham. https://doi.org/10.1007/978-3-030-57393-5_7
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