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Metastatic Disease

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Musculoskeletal Imaging

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Abstract

Metastatic bone disease is common. It is detected in up to 65–75% of patients with breast or prostate cancer and in over 35% of patients with lung cancer. Metastatic bone disease can cause a variety of symptoms and is often associated with a poorer prognosis and high social and health care costs. Early and accurate diagnosis of bone metastases is therefore crucial. The patterns and presentation of metastatic bone disease are quite heterogeneous and necessitate good knowledge of the possibilities and limitations of each imaging modality. Bone metastases commonly localize to the spinal column, pelvis, shoulder, and distal femur. The chapter reviews the pathophysiology and radiological features of bone metastases in different imaging modalities, especially MRI, as it is the most accurate technique to detect bone metastases using morphological and functional information and is also helpful in follow-up after treatment.

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Author information

Authors and Affiliations

  1. Department of Radiology, Clinica Girona, Diagnostic Imaging Institute (IDI), University of Girona, Girona, Spain

    Joan C. Vilanova

  2. Professor of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA

    Michael E. Mulligan

  3. G. Victor Rohrer Professor of Radiology Education Professor of Radiology and Orthopedics, Penn State Hershey Medical Center, Hershey, Pennsylvania, USA

    Donald J. Flemming

  4. Professor of Radiology Uniformed Services University of the Health Sciences Staff Radiologist Musculoskeletal Section Department of Radiology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA

    Mark D. Murphey

Authors
  1. Joan C. Vilanova
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  2. Michael E. Mulligan
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  3. Donald J. Flemming
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  4. Mark D. Murphey
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Corresponding author

Correspondence to Joan C. Vilanova .

Editor information

Editors and Affiliations

  1. Envision Physician Services, Plantation, FL, USA

    Thomas Pope

  2. Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

    Johannes L. Bloem

  3. Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, USA

    William B. Morrison

  4. St. Luke’s Radiology Oxford Ltd, Oxford, UK

    David John Wilson

  5. Department of Medical Imaging, University Health Network, Toronto, Canada

    Lawrence White

Section Editor information

  1. Leiden University Medical Center, Leiden, Netherlands

    Johan L. Bloem

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Vilanova, J.C., Mulligan, M.E., Flemming, D.J., Murphey, M.D. (2023). Metastatic Disease. In: Pope, T., Bloem, J.L., Morrison, W.B., Wilson, D.J., White, L. (eds) Musculoskeletal Imaging. Springer, Cham. https://doi.org/10.1007/978-3-030-57376-8_91-1

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  • DOI: https://doi.org/10.1007/978-3-030-57376-8_91-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-57376-8

  • Online ISBN: 978-3-030-57376-8

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