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EUS Characterization of Focal Pancreatic Masses

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Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy

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Abstract

Across Europe, the number of patients dying from pancreatic ductal adenocarcinoma (PDAC) has increased by more than 60% since 1990. Early detection of PDAC and risk stratification of its cystic precursor lesions facilitates long-term survival. A majority of small solid pancreatic lesions are not PDAC, but pancreatic neuroendocrine neoplasms, metastases, and a variety of other entities, most of them associated with a much better outcome. In surgical cohorts operated for the suspicion of PDAC, 5–13% of cases have a final diagnosis other than PDAC, in particular focal autoimmune pancreatitis. Therefore, early detection and precise differentiation of solid and cystic pancreatic lesions is a diagnostic challenge. This chapter reviews the pivotal role of multimodal EUS imaging including B-Mode, contrast-enhanced techniques, and elastography for the reliable characterization of focal pancreatic lesions.

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Authors and Affiliations

  1. Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Craiova, Romania

    Adrian Saftoiu

  2. Gastroenterology Department, Ponderas Academic Hospital, Bucharest, Romania

    Adrian Saftoiu

  3. Department for Internal Medicine, Krankenhaus Märkisch Oderland GmbH, Strausberg/Wriezen, Germany

    Christian Jenssen

  4. Brandenburg Institute for Clinical Ultrasound, Medical University Brandenburg, Neuruppin, Germany

    Christian Jenssen

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  1. Adrian Saftoiu
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  2. Christian Jenssen
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Editors and Affiliations

  1. Division of Gastroenterology and Gastrointestinal Endoscopy IRCCS, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy

    Pier Alberto Testoni

  2. Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan

    Haruhiro Inoue

  3. Department of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, FL, USA

    Michael B. Wallace

Section Editor information

  1. Gastrointestinal Endoscopy Unit, Vita‐Salute San Raffaele University, Milan, Italy

    Pier Alberto Testoni

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Saftoiu, A., Jenssen, C. (2022). EUS Characterization of Focal Pancreatic Masses. In: Testoni, P.A., Inoue, H., Wallace, M.B. (eds) Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-56993-8_106

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