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Molecular Genetics in Indolent Lymphomas

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Indolent Lymphomas

Part of the book series: Hematologic Malignancies ((HEMATOLOGIC))

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Abstract

The genetic portrait of indolent lymphomas has evolved considerably as the implementation of new technologies has shaped our ability to document the genetic features of these tumors, revealing what defines them collectively and discriminates them one from another. In the first part of this chapter, we describe how genetics has shaped our understanding of the complex molecular biology of indolent lymphomas, exemplified by its prototypic entity, follicular lymphoma (FL). In the second part, we provide a clinical perspective on how genetics is increasingly utilized to improve diagnostic and therapeutic approaches in patients with various indolent lymphomas.

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Authors and Affiliations

  1. Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK

    Jude Fitzgibbon

  2. Department of Medicine III, LMU Hospital, Munich, Germany

    Oliver Weigert

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  1. Jude Fitzgibbon
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  1. Department of Medicine III, LMU Hospital, München, Bayern, Germany

    Martin Dreyling

  2. Azienda Ospedaliera Nazionale SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

    Marco Ladetto

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Fitzgibbon, J., Weigert, O. (2021). Molecular Genetics in Indolent Lymphomas. In: Dreyling, M., Ladetto, M. (eds) Indolent Lymphomas . Hematologic Malignancies. Springer, Cham. https://doi.org/10.1007/978-3-030-55989-2_2

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