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How Manipulating the Microbiome Can Affect the Outcome Following Bariatric Surgery

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Difficult Decisions in Bariatric Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY))

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Abstract

Bariatric surgery alters the composition and function of the gut microbiome. An increase in microbial diversity and gene richness translates to changes in metabolomic profiles that corelate with weight loss and comorbidity resolution, even though mechanistic explanation is lacking. In addition to its role on metabolic improvement, gut microbiome may influence the occurrence and course of short-term complications such as surgical site infection and leaks. Obese patients have a baseline dysbiosis as a result of various factors, diet being the most important and easily modifiable before and after surgery. A high-fiber low-fat regime translates to a healthier gastrointestinal community and better outcomes. Probiotics, prebiotics and symbiotics and more novel strategies such as fecal microbiota transplant are under interrogation in this context.

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Author information

Authors and Affiliations

  1. Gastrointestinal Surgery Department, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain

    Romina Pena

  2. Bariatric and Upper Gastrointestinal Surgery, Gastrointestinal Surgery Department, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain

    José M. Balibrea

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  1. Romina Pena
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  2. José M. Balibrea
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Editor information

Editors and Affiliations

  1. Department of Surgery, University of Chicago, Chicago, IL, USA

    John Alverdy

  2. Department of Surgery, University of Chicago, Chicago, IL, USA

    Yalini Vigneswaran

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Pena, R., Balibrea, J.M. (2021). How Manipulating the Microbiome Can Affect the Outcome Following Bariatric Surgery. In: Alverdy, J., Vigneswaran, Y. (eds) Difficult Decisions in Bariatric Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-55329-6_37

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  • DOI: https://doi.org/10.1007/978-3-030-55329-6_37

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-55328-9

  • Online ISBN: 978-3-030-55329-6

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