Abstract
The cutaneous vascular system is capable of circulating high amounts of blood. As cardiovascular function is strongly dependent on the circulating blood volume, conditions affecting extensive body surface areas have a major health impact.
Several conditions can lead to erythroderma, a clinical syndrome characterized by cutaneous inflammation covering 90% or more of the skin surface.
One of the consequences of erythroederma is low circulating blood volume causing impairement of ventricular filling, which in turn activates other compensatory mechanisms.
In addition to supportive care measures, treatment should address the primary cutaneous inflammation. Additional fluid administration should be avoided, as it will finally be entrapped in the dilated cutaneous capillary system resulting in further edema.
Erythroderma is one of the most severe dermatological conditions, sometimes resulting in death. Most patients die of cardiovascular complications and proper management of the condition can prove life-saving.
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Salavastru, C., Cretu, S., Tiplica, G.S. (2021). Erythroderma and Cardiac Function. In: Salavastru, C., Murrell, D.F., Otton, J. (eds) Skin and the Heart. Springer, Cham. https://doi.org/10.1007/978-3-030-54779-0_24
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