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Genitourinary Neuroendocrine Neoplasms

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The Spectrum of Neuroendocrine Neoplasia

Abstract

Neuroendocrine neoplasms (NENs) of the genitourinary tract are uncommon, but the pathologist has to be prepared to recognize them and to assess the morphophenotypic factors that can drive their treatment and prognosis. NENs have been described in the kidney, urinary bladder, prostate, testes, uterine cervix, uterine corpus, and ovaries. The clinico-pathological features and the nomenclature of these neoplasms may vary from site to site. This chapter systematically reviews the spectrum of genitourinary NEN within the context of a unitary vision of the diagnostic criteria and classification, paralleling the scheme recently proposed by the World Health Organization and the International Agency for Research on Cancer (IARC).

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Authors and Affiliations

  1. Pathology Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy

    Silvia Uccella

  2. Department of Pathology and Molecular Genetics/Oncologic Pathology Group, Biomedical Research Institute of Lleida (IRBLleida), University of Lleida, CIBERONC, Lleida, Spain

    Xavier Mathias-Guiu

  3. Department of Pathology, University Hospital of Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain

    Xavier Mathias-Guiu

  4. Institute of Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland

    Stefano La Rosa

Authors
  1. Silvia Uccella
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  2. Xavier Mathias-Guiu
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  3. Stefano La Rosa
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Correspondence to Silvia Uccella .

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Editors and Affiliations

  1. University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA

    Sylvia L. Asa

  2. Institute of Pathology, University Hospital of Lausanne, Lausanne, Vaud, Switzerland

    Stefano La Rosa

  3. Department of Pathology, University Health Network, Toronto, ON, Canada

    Ozgur Mete

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Uccella, S., Mathias-Guiu, X., La Rosa, S. (2021). Genitourinary Neuroendocrine Neoplasms. In: Asa, S.L., La Rosa, S., Mete, O. (eds) The Spectrum of Neuroendocrine Neoplasia. Springer, Cham. https://doi.org/10.1007/978-3-030-54391-4_14

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  • DOI: https://doi.org/10.1007/978-3-030-54391-4_14

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