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Neoplasms of the Oral Cavity and Oropharynx

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Textbook of Clinical Otolaryngology

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Abstract

Oral and oropharyngeal cancers (OPC) are a major global health concern traditionally caused by tobacco and alcohol abuse. The last decade has revealed the emerging role of Human Papilloma Virus (HPV) as a major etiological factor for oropharyngeal cancer predominantly in the developed world. Cancers affecting both these subsites are distinct entities. Changes have been incorporated in the recent staging system with recognition of the prognostic importance of depth of invasion (DOI) and extranodal extension (ENE) for oral cancers as well as the favourable biology of HPV-related cancers necessitating a separate staging system and attempts at deintensification of treatment. Oral cancers are predominantly treated by primary surgery and oropharyngeal cancers with non-surgical approaches. The advent of transoral robotic surgery (TORS) has resulted in its exploration of its role for select oropharyngeal cancers. There has been an emergence of recent new data which has resulted in changes in traditional management protocols of these cancers.

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Authors and Affiliations

  1. Apollo Group of Hospitals, Navi Mumbai, Maharashtra, India

    Anil K. D’Cruz

  2. Department of Oncology, Apollo Hospital, Navi Mumbai, Maharashtra, India

    Anil K. D’Cruz

  3. Department of Head and Neck Oncology, Narayana Superspeciality Hospitals, Howrah, West Bengal, India

    Harsh Dhar

  4. Department of Head Neck Oncology, Apollo Hospital, Navi Mumbai, Maharashtra, India

    Khuzema Fatehi

  5. Department of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India

    Richa Vaish

  6. Department of Head and Neck Oncology, Homi Bhabha National Institute, Mumbai, Maharashtra, India

    Richa Vaish

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  1. Anil K. D’Cruz
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  2. Harsh Dhar
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  3. Khuzema Fatehi
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  4. Richa Vaish
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  1. Hamad Medical Corporation, Doha, Qatar

    Abdulsalam Al-Qahtani

  2. Hamad Medical Corporation, Doha, Qatar

    Hassan Haidar

  3. Hamad Medical Corporation, Doha, Qatar

    Aisha Larem

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D’Cruz, A.K., Dhar, H., Fatehi, K., Vaish, R. (2021). Neoplasms of the Oral Cavity and Oropharynx. In: Al-Qahtani, A., Haidar, H., Larem, A. (eds) Textbook of Clinical Otolaryngology. Springer, Cham. https://doi.org/10.1007/978-3-030-54088-3_38

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