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Endoscopy and Endoscopic Ablative Therapies in GERD and Barrett’s Esophagus

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Multidisciplinary Management of Gastroesophageal Reflux Disease
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Abstract

Endoscopy is an important diagnostic and therapeutic tool for managing gastroesophageal reflux disease (GERD) and Barrett’s esophagus. Endoscopic findings such as erosive esophagitis, luminal narrowing, and metaplastic turnover of the epithelium are indicatives for GERD. Endoscopic fundoplication methods have been developed, some showed promising results, many left the market already. Biopsy sampling in GERD should be limited to cases with suspicion of Barrett’s metaplasia of at least 1 cm extension into the distal esophagus and withheld in case of massive inflammation. Surveillance of Barrett’s esophagus aims to detect early neoplasia. Advanced endoscopic imaging like chromoendoscopy or narrow-band imaging (NBI) can help to identify and characterize neoplastic lesions. Endoscopic treatment by endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), or radiofrequency ablation (RFA) aims to prevent progression into (advanced) esophageal cancer.

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Dolak, W. (2021). Endoscopy and Endoscopic Ablative Therapies in GERD and Barrett’s Esophagus. In: Schoppmann, S.F., Riegler, M. (eds) Multidisciplinary Management of Gastroesophageal Reflux Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-53751-7_3

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