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Alpha-agonists in Pediatric Procedural Sedation

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Sedation and Analgesia for the Pediatric Intensivist

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Abstract

Dexmedetomidine (DEX), a central alpha-2-agonist, is being increasingly used in outpatient procedural sedation. Recent concerns about the time-honored hypnotic chloral hydrate’s carcinogenicity, genotoxicity, and more importantly lack of availability in the US market have led to DEX as a viable alternative to chloral hydrate in procedural sedation both as an intravenous (IV) medication and an intranasal medication.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA

    Pradip P. Kamat

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  1. Pradip P. Kamat
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Correspondence to Pradip P. Kamat .

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Editors and Affiliations

  1. Associate Professor of Pediatrics, Emory University School of Medicine, Department of Pediatrics, Division of Pediatric Critical Care Medicine, Children’s Healthcare of Atlanta at Egleston, Atlanta, GA, USA

    Pradip P. Kamat

  2. Professor of Pediatrics/Pediatric Critical Care, University of Louisville, “Just For Kids” Critical Care Center, Norton Children’s Hospital, Louisville, KY, USA

    John W. Berkenbosch

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Kamat, P.P. (2021). Alpha-agonists in Pediatric Procedural Sedation. In: Kamat, P.P., Berkenbosch, J.W. (eds) Sedation and Analgesia for the Pediatric Intensivist. Springer, Cham. https://doi.org/10.1007/978-3-030-52555-2_29

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  • DOI: https://doi.org/10.1007/978-3-030-52555-2_29

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-52554-5

  • Online ISBN: 978-3-030-52555-2

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