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Metabolomics of Gastric Cancer

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Cancer Metabolomics

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1280))

Abstract

Gastric cancer is the fourth most common malignancy worldwide and the third leading cause of cancer deaths. Recent metabolomics research has advanced our understanding of the relationship between metabolic reprogramming and gastric cancer progression and led to the discovery of metabolic targets for potential clinical applications and therapeutic interventions. As a powerful tool for metabolite and flux measurement, metabolomics not only allows a comprehensive analysis of metabolites and related metabolic pathways but also can investigate the interactions between gastric cancer cells and tumour microenvironment as well as between the cancer cells and gastric microbiome. In this chapter, we aim to summarize the recent advances in gastric cancer metabolism and discuss the applications of metabolomics for target discovery in gastric cancer.

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Authors and Affiliations

  1. UCLA School of Dentistry, Los Angeles, CA, USA

    Wroocha Kadam & Feng Li

  2. UCLA School of Medicine, Los Angeles, CA, USA

    Bowen Wei

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  1. Wroocha Kadam
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  2. Bowen Wei
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Correspondence to Feng Li .

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  1. University of California, Los Angeles, Los Angeles, CA, USA

    Shen Hu

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Kadam, W., Wei, B., Li, F. (2021). Metabolomics of Gastric Cancer. In: Hu, S. (eds) Cancer Metabolomics. Advances in Experimental Medicine and Biology, vol 1280. Springer, Cham. https://doi.org/10.1007/978-3-030-51652-9_20

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