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Image-Guided Robotic Radiosurgery for the Treatment of Drug-Refractory Epilepsy

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CyberKnife NeuroRadiosurgery

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Abstract

Stereotactic radiosurgery represents an attractive alternative option to resective surgery to treat medically refractory epilepsy. The ablation of an epileptic focus, especially when performed through frameless image-guided radiosurgery, is a minimally invasive treatment devoid of the risks of open surgical procedures. Radiosurgery has been attempted to treat patients with neocortical, hippocampal, or diencephalic seizure foci for whom invasive mapping is not necessary. Disconnective procedures such as radiosurgical callosotomy can be performed as well. In this article, we review the state-of-the- art of radiosurgical treatment of epilepsy, with specific focus on robotic image-guided radiosurgery.

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Author information

Authors and Affiliations

  1. Brain Radiosurgery, Cyberknife Center, CDI, Milan, Italy

    Pantaleo Romanelli

  2. Alma Mater Studiorum University of Bologna, Bologna, Italy

    Alfredo Conti

  3. IRCCS ISNB Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy

    Alfredo Conti

  4. Department of Neurosurgery, Charité Faculty of Medicine, Berlin, Germany

    Alfredo Conti

Authors
  1. Pantaleo Romanelli
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  2. Alfredo Conti
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Corresponding author

Correspondence to Pantaleo Romanelli .

Editor information

Editors and Affiliations

  1. Associate Professor of Neurosurgery, Alma Mater Studiorum University of Bologna, Bologna, Italy

    Alfredo Conti

  2. Scientific Director, AB Medica, Milano, Italy

    Pantaleo Romanelli

  3. Assistant Professor, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece

    Evangelos Pantelis

  4. Associate Professor, Department of Radiation Oncology, Stanford University Cancer Center, Stanford, CA, USA

    Scott G. Soltys

  5. Associate Professor, Department of Neurosurgery and Radiosurgery Center, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea (Republic of)

    Young Hyun Cho

  6. Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Michael Lim

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Romanelli, P., Conti, A. (2020). Image-Guided Robotic Radiosurgery for the Treatment of Drug-Refractory Epilepsy. In: Conti, A., Romanelli, P., Pantelis, E., Soltys, S., Cho, Y., Lim, M. (eds) CyberKnife NeuroRadiosurgery . Springer, Cham. https://doi.org/10.1007/978-3-030-50668-1_49

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