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Paragangliomas of the Head and Neck

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CyberKnife NeuroRadiosurgery

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Abstract

Paragangliomas of the head and neck are rare neoplasms that arise from the paraganglia of the chemoreceptor system. The ideal treatment for patients with paraganglioma remains a matter of debate. Treatment options include surgery, endovascular embolization, fractionated radiation therapy, and stereotactic radiosurgery, alone or in combination. The difficulties associated with the surgical treatment of paragangliomas are primarily related to excessive intraoperative bleeding. Fractionated radiation therapy for head and neck paragangliomas is a safe and efficient treatment associated with a high probability of cure and a low incidence of morbidity. Stereotactic radiosurgery has proven to be highly effective in the treatment of paragangliomas and conveys a relatively low risk of complications. The CyberKnife is a frameless radiosurgery system in which an orthogonal pair of X-ray cameras is coupled with a linear accelerator that is dynamically manipulated by a robotic arm with six degrees of freedom. In addition to delivering a highly conformal dose distribution, the treatment of complexly shaped lesions is made more accessible by the system’s non-isocentric geometry. This allows an extremely homogeneous dose delivery. We report the CyberKnife treatment for single-session radiosurgery and the emerging role of multisession radiosurgery for the rare neuropathology of paragangliomas.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, CyberKnife Radiosurgery Center, Medicana International Ankara Hospital, Ankara, Turkey

    Kaan Oysul

  2. Department of Neurosurgery, CyberKnife Radiosurgery Center, Medicana International Ankara Hospital, Ankara, Turkey

    Sait Sirin

Authors
  1. Kaan Oysul
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  2. Sait Sirin
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Corresponding author

Correspondence to Sait Sirin .

Editor information

Editors and Affiliations

  1. Associate Professor of Neurosurgery, Alma Mater Studiorum University of Bologna, Bologna, Italy

    Alfredo Conti

  2. Scientific Director, AB Medica, Milano, Italy

    Pantaleo Romanelli

  3. Assistant Professor, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Athens, Greece

    Evangelos Pantelis

  4. Associate Professor, Department of Radiation Oncology, Stanford University Cancer Center, Stanford, CA, USA

    Scott G. Soltys

  5. Associate Professor, Department of Neurosurgery and Radiosurgery Center, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea (Republic of)

    Young Hyun Cho

  6. Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Michael Lim

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Oysul, K., Sirin, S. (2020). Paragangliomas of the Head and Neck. In: Conti, A., Romanelli, P., Pantelis, E., Soltys, S., Cho, Y., Lim, M. (eds) CyberKnife NeuroRadiosurgery . Springer, Cham. https://doi.org/10.1007/978-3-030-50668-1_32

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