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Secondary Lung Cancer

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Image-Guided Interventions in Oncology

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Abstract

Lung metastases are identified in 30–55% of all cancer patients and are the second most frequent site of metastatic spread for colorectal and breast cancer. Thermal ablation such as radiofrequency ablation (RFA), microwave ablation (MWA), and cryoablation of lung oligometastasis is a viable substitute for radiation therapy and surgical resection in appropriately selected patients. In this chapter, we discuss the current evidence supporting the use of thermal ablation in patients with pulmonary oligometastasis, technical considerations of the procedure, patient selection, potential complications, and reported outcomes. Additionally, we will discuss the data for surgery and radiation therapy on the oligometastatic patient and how ablation can fit into the paradigm.

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Abbreviations

CIRSE:

Cardiovascular and Interventional Radiology Society of Europe

CRC:

Colorectal cancer

EGFR-TKI:

Epidermal growth factor receptor tyrosine kinase inhibitors

GGO:

Ground-glass opacity

LCT:

Local consolidative therapy

MWA:

Microwave ablation

OS:

Overall survival

PET/CT:

Positron-emission tomography/computed tomography

PFS:

Progression-free survival

RFA:

Radiofrequency ablation

SBRT:

Stereotactic body radiotherapy

SCC:

Squamous cell carcinoma

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Author information

Authors and Affiliations

  1. Interventional Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Eduardo A. Lacayo & Stephen Solomon

  2. Medical Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Alan Ho

Authors
  1. Eduardo A. Lacayo
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  2. Stephen Solomon
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  3. Alan Ho
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Corresponding author

Correspondence to Eduardo A. Lacayo .

Editor information

Editors and Affiliations

  1. Professor of Radiology, Oncology & Surgery, Vascular and Interventional Radiology Johns Hopkins Hospital, Baltimore, MD, USA

    Christos Georgiades

  2. Professor of Radiology and Medicine (Oncology), Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA

    Hyun S. Kim

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Lacayo, E.A., Solomon, S., Ho, A. (2020). Secondary Lung Cancer. In: Georgiades, C., Kim, H. (eds) Image-Guided Interventions in Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-48767-6_5

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  • DOI: https://doi.org/10.1007/978-3-030-48767-6_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-48766-9

  • Online ISBN: 978-3-030-48767-6

  • eBook Packages: MedicineMedicine (R0)

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