Abstract
Chest pain is one of the most commonly encountered clinical presentations in the inpatient setting. Given the broad differential diagnosis of chest discomfort, the initial evaluation can be challenging. Life-threatening conditions such as acute myocardial infarction, aortic dissection, pulmonary embolism, and tension pneumothorax need to be recognized promptly in order to prevent major morbidity and mortality. A thorough history and physical examination can often limit unnecessary testing, particularly in patients who are at a low risk for serious cardiovascular disease. Identifying characteristic features of the pain such as its onset, duration, character, and possible triggers and alleviating factors can help narrow the differential diagnosis and guide further diagnostic testing. In addition, all patients with new onset chest pain should receive an electrocardiogram and a chest X-ray as part of a rapid initial assessment. This chapter describes the main causes of chest pain and helps guide the initial evaluation based on history, physical examination, and initial testing.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- ACS:
-
Acute coronary syndrome
- CAD:
-
Coronary artery disease
- CTA:
-
Computed tomography angiogram
- CXR:
-
Chest X-ray
- ECG:
-
Electrocardiogram
- MI:
-
Myocardial infarction
- NSTEMI:
-
Non-ST-elevation myocardial infarction
- NTG:
-
Nitroglycerin
- PE:
-
Pulmonary embolism
- PTX:
-
Pneumothorax
- STEMI:
-
ST-elevation myocardial infarction
- TTE:
-
Transthoracic echocardiogram
References
Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, et al. ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2012;126(25):3097–137.
Prinzmetal M, Kennamer R, Merliss R, Wada T, Bor N. Angina pectoris. I. A variant form of angina pectoris; preliminary report. Am J Med. 1959;27:375–88.
Braunwald E, Jones RH, Mark DB, Brown J, Brown L, Cheitlin MD, et al. Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. Circulation. 1994;90(1):613–22.
McSweeney JC, Cody M, O'Sullivan P, Elberson K, Moser DK, Garvin BJ. Women’s early warning symptoms of acute myocardial infarction. Circulation. 2003;108(21):2619–23.
Culic V, Eterovic D, Miric D, Silic N. Symptom presentation of acute myocardial infarction: influence of sex, age, and risk factors. Am Heart J. 2002;144(6):1012–7.
Canto JG, Shlipak MG, Rogers WJ, Malmgren JA, Frederick PD, Lambrew CT, et al. Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain. JAMA. 2000;283(24):3223–9.
Thygesen K, Alpert JS, Jaffe AS, Simoons ML, Chaitman BR, White HD, et al. Third universal definition of myocardial infarction. Glob Heart. 2012;7(4):275–95.
Troughton RW, Asher CR, Klein AL. Pericarditis. Lancet. 2004;363(9410):717–27.
Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA. 2000;283(7):897–903.
Weber T, Hogler S, Auer J, Berent R, Lassnig E, Kvas E, et al. D-dimer in acute aortic dissection. Chest. 2003;123(5):1375–8.
Anderson FA Jr, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, et al. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study. Arch Intern Med. 1991;151(5):933–8.
Stein PD, Terrin ML, Hales CA, Palevsky HI, Saltzman HA, Thompson BT, et al. Clinical, laboratory, roentgenographic, and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease. Chest. 1991;100(3):598–603.
Chan TC, Vilke GM, Pollack M, Brady WJ. Electrocardiographic manifestations: pulmonary embolism. J Emerg Med. 2001;21(3):263–70.
Szucs MM Jr, Brooks HL, Grossman W, Banas JS Jr, Meister G, Dexter L, et al. Diagnostic senstivity of laboratory findings in acute pulmonary embolism. Ann Intern Med. 1971;74(2):161–6.
Wells PS, Anderson DR, Rodger M, Stiell I, Dreyer JF, Barnes D, et al. Excluding pulmonary embolism at the bedside without diagnostic imaging: management of patients with suspected pulmonary embolism presenting to the emergency department by using a simple clinical model and d-dimer. Ann Intern Med. 2001;135(2):98–107.
Fruergaard P, Launbjerg J, Hesse B, Jorgensen F, Petri A, Eiken P, et al. The diagnoses of patients admitted with acute chest pain but without myocardial infarction. Eur Heart J. 1996;17(7):1028–34.
Traube M, Albibi R, McCallum RW. High-amplitude peristaltic esophageal contractions associated with chest pain. JAMA. 1983;250(19):2655–9.
Ho KY, Ng WL, Kang JY, Yeoh KG. Gastroesophageal reflux disease is a common cause of noncardiac chest pain in a country with a low prevalence of reflux esophagitis. Dig Dis Sci. 1998;43(9):1991–7.
McDonald GB, Sharma P, Hackman RC, Meyers JD, Thomas ED. Esophageal infections in immunosuppressed patients after marrow transplantation. Gastroenterology. 1985;88(5):1111–7.
Kikendall JW. Pill esophagitis. J Clin Gastroenterol. 1999;28(4):298–305.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Korjian, S., Gibson, C.M. (2020). Chest Pain. In: Wells, B., Quintero, P., Southmayd, G. (eds) Handbook of Inpatient Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-47868-1_24
Download citation
DOI: https://doi.org/10.1007/978-3-030-47868-1_24
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-47867-4
Online ISBN: 978-3-030-47868-1
eBook Packages: MedicineMedicine (R0)