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Progress on Total Artificial Heart for Pediatric Patients

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Mechanical Support for Heart Failure

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Abstract

Mechanical circulatory support devices, especially ventricular assist devices (VADs), have been increasingly used for both adult and pediatric patients with end-stage heart failure. However, patients with congenital heart disease (CHD) are often not mechanically supported because they are at higher risk of VAD complications. CHD often involves both ventricles, and in such cases, either a biventricular assist device or total artificial heart (TAH) is needed. No pediatric TAHs exist other than SynCardia 50 cc TAH (SynCardia Systems, Inc., Tucson, AZ), which is intended only for patients with a body surface area of ≥1.2 m2. Therefore, new TAHs for pediatric patients are under development to fill this gap.

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Author information

Authors and Affiliations

  1. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland Clinic, Cleveland, OH, USA

    Kiyotaka Fukamachi MD, PhD & Jamshid H. Karimov MD, PhD

  2. Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA

    Takuma Miyamoto MD, PhD

Authors
  1. Kiyotaka Fukamachi MD, PhD
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  2. Jamshid H. Karimov MD, PhD
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  3. Takuma Miyamoto MD, PhD
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Corresponding author

Correspondence to Kiyotaka Fukamachi MD, PhD .

Editor information

Editors and Affiliations

  1. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Jamshid H. Karimov

  2. Lerner Research Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Kiyotaka Fukamachi

  3. Kaufman Center for Heart Failure Heart, Thoracic, and Vascular Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Cleveland Clinic, Cleveland, OH, USA

    Randall C. Starling

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Fukamachi, K., Karimov, J.H., Miyamoto, T. (2020). Progress on Total Artificial Heart for Pediatric Patients. In: Karimov, J., Fukamachi, K., Starling, R. (eds) Mechanical Support for Heart Failure . Springer, Cham. https://doi.org/10.1007/978-3-030-47809-4_38

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  • DOI: https://doi.org/10.1007/978-3-030-47809-4_38

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-47808-7

  • Online ISBN: 978-3-030-47809-4

  • eBook Packages: MedicineMedicine (R0)

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