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Techniques of Ovarian Transplantation

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Female and Male Fertility Preservation

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Abstract

Since the birth of the first baby after auto-transplantation of frozen-thawed ovarian tissue in 2004, several groups have reported worldwide their experience with this technique. Despite the surgical heterogeneity present among these groups, several fundamental principles apply to all of them, which make in turn success rates stable: vascularization, reduction of ischemia time, and placement of fragments.

Although most groups have worked with slow-freezing, it is very likely that vitrification could replace the former because of its simplicity and equivalent results. Several groups are working on different research areas to improve follicle survival and OCT performance. Growth factors, hormones, matrix scaffolds, and robotics surgery may await the future of this young yet stablished fertility preservation procedure.

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Abbreviations

AMH:

Anti-Müllerian hormone

OCC:

Ovarian cortex cryopreservation

OCT:

Ovarian cortex transplantation

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Authors and Affiliations

  1. IVIRMA Valencia, Plaza Policía Local, Valencia, Spain

    Jessica Subirá

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  1. Jessica Subirá
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Editors and Affiliations

  1. Reproductive Medicine and Fertility Preservation, Hôpital Antoine-Béclère, Clamart, France

    Michael Grynberg

  2. Division of Reproductive Endocrinology and Infertility-Department Obstetrics, Gynecology and Reproductive Sciences, University of Miami, Miami, FL, USA

    Pasquale Patrizio

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Subirá, J. (2022). Techniques of Ovarian Transplantation. In: Grynberg, M., Patrizio, P. (eds) Female and Male Fertility Preservation. Springer, Cham. https://doi.org/10.1007/978-3-030-47767-7_33

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  • DOI: https://doi.org/10.1007/978-3-030-47767-7_33

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