Skip to main content

Indwelling Pleural Catheters Versus Talc Pleurodesis for Recurrent Symptomatic Malignant Pleural Effusions

  • Chapter
  • First Online:
Difficult Decisions in Thoracic Surgery

Abstract

Malignant pleural effusions can destroy quality of life in patients with advanced cancer. The majority of patients with malignant pleural effusions will develop symptoms that necessitate intervention. Quality of life is enhanced by alleviating symptoms and reducing interactions with the healthcare system, while minimizing treatment-related complications. We evaluate the use of indwelling pleural catheters versus pleurodesis for the management of symptomatic malignant pleural effusions. We recommend that for patients with recurrent symptomatic malignant pleural effusions, placement of an indwelling pleural catheter or talc pleurodesis is equally appropriate and efficacious for the relief of dyspnea. In contrast, for patients with recurrent symptomatic malignant pleural effusions, indwelling pleural catheter placement is superior to talc pleurodesis based on the reduced number of hospital days and need for reinterventions.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Chernow B, Sahn SA. Carcinomatous involvement of the pleural: an analysis of 96 patients. Am J Med. 1977;63:695–702.

    Article  CAS  Google Scholar 

  2. Roberts ME, Neville E, Berrisford RG, Antunes G, Ali NJ, BTS Pleural Disease Guideline Group. Management of a malignant pleural effusion: British Thoracic Society Pleural Disease Guideline 2010. Thorax. 2010;65(Suppl 2):ii32–40.

    Article  Google Scholar 

  3. Ost DE, Niu J, Zhao H, Grosu H, Giordano SH. Quality gaps and comparative effectiveness of management strategies for recurrent malignant pleural effusions. Chest. 2018;153:438–52.

    Article  Google Scholar 

  4. Burrows CM, Mathews WC, Colt HG. Predicting survival in patients with recurrent symptomatic malignant pleural effusions: an assessment of the prognostic values of physiologic, morphologic, and quality of life measures of extent of disease. Chest. 2000;117(1):73–8.

    Article  CAS  Google Scholar 

  5. Feller-Kopman DJ, Reddy CB, DeCamp MM, Diekemper RL, Gould MK, Henry T, Iyer NP, Lee YCG, Lewis SZ, Maskell NA, Rahman NM, Sterman DH, Wahidi MM, Balekian AA. Management of malignant pleural effusions. An official ATS/STS/STR clinical practice guideline. Am J Respir Crit Care Med. 2018;198(7):839–49.

    Article  Google Scholar 

  6. Boshuizen RC, Vd Noort V, Burgers JA, Herder GJM, Hashemi SMS, Hiltermann TJN, Kunst PW, Stigt JA, van den Heuvel MM. A randomized controlled trial comparing indwelling pleural catheters with talc pleurodesis (NVALT-14). Lung Cancer. 2017;108:9–14.

    Article  CAS  Google Scholar 

  7. Boshuizen RC, Vincent AD, van den Heuvel MM. Comparison of modified Borg scale and visual analog scale dyspnea scores in predicting re-intervention after drainage of malignant pleural effusion. Support Care Cancer. 2013;21(11):3109–16.

    Article  Google Scholar 

  8. Boshuizen R, Vincent A, Kunst P, Burgers S, van den Heuvel M. A Dutch web-survey on management of malignant pleural effusions. Eur Respir J. 2011;38:p3560.

    Google Scholar 

  9. Davies HE, Mishra EK, Kahan BC, Wrightson JM, Stanton AE, Guhan A, Davies CW, Grayez J, Harrison R, Prasad A, Crosthwaite N, Lee YC, Davies RJ, Miller RF, Rahman NM. Effect of an indwelling pleural catheter vs chest tube and talc pleurodesis for relieving dyspnea in patients with malignant pleural effusion: The TIME2 randomized controlled trial. JAMA. 2012;307(22):2383–9.

    Article  CAS  Google Scholar 

  10. Demmy TL, Gu L, Burkhalter JE, Toloza EM, D’Amico TA, Sutherland S, Wang X, Archer L, Veit LJ, Kohman L, Cancer and Leukemia Group B. Optimal management of malignant pleural effusions (results of CALGB 30102). J Natl Compr Cancer Netw. 2012;10(8):975–82.

    Article  Google Scholar 

  11. Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG. Effect of an indwelling pleural catheter vs talc pleurodesis on hospitalization days in patients with malignant pleural effusion: the AMPLE randomized clinical trial. JAMA. 2017;318(19):1903–12.

    Article  Google Scholar 

  12. Freeman RK, Ascioti AJ, Mahidhara RS. A propensity-matched comparison of pleurodesis or tunneled pleural catheter in patients undergoing diagnostic thoracoscopy for malignancy. Ann Thorac Surg. 2013;96(1):259–63.

    Article  Google Scholar 

  13. Hunt BM, Farivar AS, Vallières E, Louie BE, Aye RW, Flores EE, Gorden JA. Thoracoscopic talc versus tunneled pleural catheters for palliation of malignant pleural effusions. Ann Thorac Surg. 2012;94(4):1053–7.

    Article  Google Scholar 

  14. Bhatnagar R, Keenan EK, Morley AJ, Kahan BC, Stanton AE, Haris M, Harrison RN, Mustafa RA, Bishop LJ, Ahmed L, West A, Holme J, Evison M, Munavvar M, Sivasothy P, Herre J, Cooper D, Roberts M, Guhan A, Hooper C, Walters J, Saba TS, Chakrabarti B, Gunatilake S, Psallidas I, Walker SP, Bibby AC, Smith S, Stadon LJ, Zahan-Evans NJ, YCG L, Harvey JE, Rahman NM, Miller RF, Maskell NA. Outpatient talc administration by indwelling pleural catheter for malignant effusion. N Engl J Med. 2018;378(14):1313–22.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Malcolm M. DeCamp .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Morgan, C.T., McCarthy, D.P., DeCamp, M.M. (2020). Indwelling Pleural Catheters Versus Talc Pleurodesis for Recurrent Symptomatic Malignant Pleural Effusions. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach. Springer, Cham. https://doi.org/10.1007/978-3-030-47404-1_51

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-47404-1_51

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-47403-4

  • Online ISBN: 978-3-030-47404-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics