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Impact of Gut Microbiota on Host by Exploring Proteomics

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Gut Microbiome and Its Impact on Health and Diseases

Abstract

Microbial colonization of intestine plays an important role in many aspects of human health. The growing availability of microbial genome sequences and advances in complementary transcriptomics and proteomics techniques are helping to better understand the link between the gut microbiome and human health. Proteomics combined with computational and bioinformatic tools and models are further aiding the progress in this field. However, many challenges still remain ahead to translate new knowledge gained from proteomics into disease diagnosis and treatment strategies. Future studies should focus on how to exploit these new technologies to advance our knowledge of gut microbiota in the context of human health and disease treatments. This book chapter discusses the application of proteomic techniques to explore gut microbial communities and future perspectives for advancing the field forward.

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Author information

Authors and Affiliations

  1. GlaxoSmithKline, Collegeville, PA, USA

    Thomas E. Angel

  2. Purdue Proteomics Facility, Bindley Bioscience Center, Purdue University, West Lafayette, IN, USA

    Uma K. Aryal

  3. Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA

    Uma K. Aryal

Authors
  1. Thomas E. Angel
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  2. Uma K. Aryal
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Correspondence to Thomas E. Angel .

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Editors and Affiliations

  1. Department of Animal and Avian Sciences, University of Maryland, College Park, College Park, MD, USA

    Debabrata Biswas

  2. Department of Nutrition and Food Science, University of Maryland, College Park, College Park, MD, USA

    Shaik O. Rahaman

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Angel, T.E., Aryal, U.K. (2020). Impact of Gut Microbiota on Host by Exploring Proteomics. In: Biswas, D., Rahaman, S.O. (eds) Gut Microbiome and Its Impact on Health and Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-47384-6_11

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