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Raman Spectroscopy

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Technology in Practical Dermatology

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Abstract

In the field of skin research, Raman spectroscopy (RS) is an analytical technique capable of measuring vibrational modes of biomolecules. Substantial technical progress in design and performance of the individual setup components like detectors and lasers as well as the combination with reflectance confocal microscopy enables chemically selective and nondestructive sample analysis with high spatial resolution in three dimensions. By improving objectivity, thanks to the molecular-specific analysis, RS bears great potential for numerous skin applications, both in vitro and ex vivo, ranging from the analysis of physiological component distribution in skin tissue, the diagnosis of pathological states or skin cancers up to pharmaceutical investigations such as drug penetration kinetics within the different skin layers.

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Author information

Authors and Affiliations

  1. Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, Siena, Italy

    Elisa Cinotti & Luca Provvidenziale

  2. Department of Dermatology, University Hospital of St-Etienne, Saint-Etienne, France

    Jean Luc Perrot

Authors
  1. Elisa Cinotti
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  2. Luca Provvidenziale
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  3. Jean Luc Perrot
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Editor information

Editors and Affiliations

  1. Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy

    Michele Fimiani

  2. Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy

    Pietro Rubegni

  3. Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy

    Elisa Cinotti

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Cinotti, E., Provvidenziale, L., Perrot, J.L. (2020). Raman Spectroscopy. In: Fimiani, M., Rubegni, P., Cinotti, E. (eds) Technology in Practical Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-45351-0_25

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  • DOI: https://doi.org/10.1007/978-3-030-45351-0_25

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-45350-3

  • Online ISBN: 978-3-030-45351-0

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