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Bioactive Compounds of Black Bean (Phaseolus vulgaris L.)

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Bioactive Compounds in Underutilized Vegetables and Legumes

Part of the book series: Reference Series in Phytochemistry ((RSP))

Abstract

Nutrition and diseases are knottily related; they cannot be separated in any way whatsoever. Epidemiological investigations have reported that consistent intake of plant-based foods, i.e., vegetables, legumes, and fruits, is associated with reduced incidence of heart-related diseases, cancer, and cardiovascular diseases. Legumes, particularly black beans (Phaseolus vulgaris L.), are popularly consumed in many parts of the world and are a staple food in Central America and East and West African countries, where they are a major source of vitamins, proteins, energy, and minerals. This review gathers up-do-date studies on this plant species and has discovered that P. vulgaris is rich in anthocyanins, flavonols, flavones, and tannins, and only twenty-eight compounds have been identified to date from this bean. One of the objectives of this review is to gather evidence available in the scientific literature on the observed biology of this bean (in vitro and in vivo studies), which is commonly rejected by many in Nigeria. Anticancer, antidiabetic, and antioxidant effects are among the most prominent activities associated with P. vulgaris, making obvious the hidden benefits that this plant species possesses. In contrast, “Phytohemagglutinin,” a toxic protein present in most common beans, includeing P. vulgaris, but cooking for at least 30 min deactivates this compound. There are indications that black beans have enormous potential as a functional food, though more pharmacological facts are needed to justify this claim. Modern metabolomics may be employed to help researchers know the compounds responsible for some of its effects.

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Abbreviations

5-HTP:

5-hydroxytryptophan

ABTS:

2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid

b.w:

Body Weight

Caco-2:

human epithelial cell line

DPPH:

2,2-diphenyl-1-picrylhydrazyl.

FST:

Force swim test

HepG2:

a human liver cancer cell line

HTRs:

induced head-twitch responses

MCF7:

a breast cancer cell line

MDA-MB231:

Cell Line human breast adenocarcinoma

PC3:

a human prostate cancer cell line

PRSC:

Peroxyl Radical Scavenging Capacity

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Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Faculty of Life Sciences, Federal University Dutsin-Ma, Dutsin-Ma, Katsina, Nigeria

    Balkisu O. Abdulrahman

  2. Department of Biochemistry, Faculty of Basic Medical Sciences, Bayero University, Kano, Nigeria

    Muntari Bala

  3. National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS, USA

    Oluwasesan M. Bello

  4. Department of Applied Chemistry, Faculty of Physical Sciences, Federal University, Dutsin-Ma, Katsina, Nigeria

    Oluwasesan M. Bello

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  1. Balkisu O. Abdulrahman
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  2. Muntari Bala
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  3. Oluwasesan M. Bello
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Correspondence to Oluwasesan M. Bello .

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Editors and Affiliations

  1. Department of Botany, Karnatak University, Dharwad, Karnataka, India

    Hosakatte Niranjana Murthy

  2. Dept of Horticultural Science, Chungbuk National University, Cheonju, Korea (Republic of)

    Kee Yoeup Paek

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Abdulrahman, B.O., Bala, M., Bello, O.M. (2020). Bioactive Compounds of Black Bean (Phaseolus vulgaris L.). In: Murthy, H.N., Paek, K.Y. (eds) Bioactive Compounds in Underutilized Vegetables and Legumes. Reference Series in Phytochemistry. Springer, Cham. https://doi.org/10.1007/978-3-030-44578-2_38-1

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  • Print ISBN: 978-3-030-44578-2

  • Online ISBN: 978-3-030-44578-2

  • eBook Packages: Springer Reference Chemistry and Mat. ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics

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