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Abstract

Schizophrenia is one of the most disabling mental disorders with a large burden of disease. Treatment options for positive, negative and cognitive symptoms of schizophrenia are limited, and a third of the patients with schizophrenia respond insufficiently to antipsychotic medications. Over the past decades, researchers have explored new treatment modalities, including neuromodulation with repetitive Transcranial Magnetic Stimulation (rTMS). The available evidence indicates that rTMS can decrease positive and negative symptoms of schizophrenia and may have procognitive effects, although effects may be modest and transient. More research is needed to investigate moderators of effect in order to optimise treatment parameters and thereby establish more durable and clinically relevant effects.

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Aleman, A., Lange, J.Dd. (2020). TMS in Psychotic Disorders. In: Dell'Osso, B., Di Lorenzo, G. (eds) Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-43356-7_7

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