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Impact of Positive Airway Pressure on Quality of Life, Excessive Daytime Sleepiness and Depressive Mood in Patients with Obstructive Sleep Apnea

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Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

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Abstract

Obstructive sleep apnea (OSA) is a syndrome with repeated obstruction of the upper airway which results in cessation of airflow, with disturbance in saturation followed by arousals from sleep. Loud snoring and witnessed apnea are the cardinal symptoms of OSA, but these symptoms cannot be self-reported. OSA can be associated with impaired quality of life, depressive mood, and excessive daytime sleepiness.

Positive airway pressure (PAP) is the first-line option in treatment of obstructive sleep apnea. For effective outcomes, PAP treatment should be at least 4 h per night. Excessive daytime sleepiness, impaired quality of life, and depressive mood are expected to be healed with CPAP treatment in OSA.

Most of the researches reported that with an effective PAP compliance, daytime symptoms, quality of life, and depressive mood can be improved; however there also studies that addressed no positive effect of CPAP therapy on these clinical outcomes.

In this chapter the association of OSA with impaired quality of life, depression, and excessive daytime sleepiness will be evaluated; moreover, impact of CPAP treatment on these self-reported outcomes will be discussed.

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Abbreviations

APAP:

Auto-adjusting positive airway pressure

AHI:

Apnea–hypopnea index

BPAP:

Bi-level positive airway pressure

CES-D:

Center for Epidemiologic Studies Depression Scale

CPAP:

Continuous positive airway pressure

EDS:

Excessive daytime sleepiness

ESS:

Epworth Sleepiness Scale

FOSQ:

Functional Outcomes of Sleep Questionnaire

HADS:

Hospital Anxiety and Depression Scale

HDRS:

Hamilton Depression Rating Scale

ODI:

Oxygen desaturation index

OSA:

Obstructive sleep apnea

PAP:

Positive airway pressure

PICO:

Patient, population or problem, intervention, comparison, and outcomes

POMS:

Profile of Mood States

QSQ:

Quebec Sleep Questionnaire

RDI:

Respiratory disturbance index

REI:

Respiratory event index

SF-36:

Short Form of the Medical Outcomes Survey

ZDS:

Zung Self-rating Depression Scale

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Author information

Authors and Affiliations

  1. Department of Pulmonary Medicine and Intensive Care, Marmara University, Istanbul, Turkey

    Baran Balcan

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  1. Baran Balcan
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Editor information

Editors and Affiliations

  1. Intensive Care Unit, Hospital General Universitario Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

  2. Department of Pathophysiology and Pulmonary Rehab, Azienda Ospedaliera dei Colli PO Monaldi, Napoli, Italy

    Giuseppe Fiorentino

  3. Innovative Technologies for the Study of Sleep Breathing Disorders, Institute for Biomedical Research and Innovation (IRIB), Italian National Research Council, Palermo, Italy

    Giuseppe Insalaco

  4. Department of Pulmonary and CC Medicine, Lenox Hill Hospital, New York, NY, USA

    Bushra Mina

  5. Department of Respiratory and CC Medicine, First Affiliated Hospital of Chongqing M, Chongqing, China

    Jun Duan

  6. Anestesia and Pediatric Intensive Care Department, University Hospital Policlinico S. Orsola-Malpighi, Bologna, Italy

    Maria Cristina Mondardini

  7. Anestesia and Pediatric Intensive Care Department, University Hospital Policlinico S. Orsola-Malpighi, Bologna, Italy

    Fabio Caramelli

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Balcan, B. (2020). Impact of Positive Airway Pressure on Quality of Life, Excessive Daytime Sleepiness and Depressive Mood in Patients with Obstructive Sleep Apnea. In: Esquinas, A.M., et al. Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-030-42998-0_28

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  • DOI: https://doi.org/10.1007/978-3-030-42998-0_28

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  • Publisher Name: Springer, Cham

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  • Online ISBN: 978-3-030-42998-0

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