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Stem Cells

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Regenerative Medicine for Spine and Joint Pain

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Abstract

Musculoskeletal disorders such as osteoarthritis and tendinopathies affect a large number of the population leading to activity limitations and disability. With limited suboptimal treatment options available and the current advancements in medicine, regenerative medicine is being looked at as the new frontier for interventional therapies. In addition to prolotherapy and PRP, stem cell therapy is quickly becoming the focus of therapeutic autologous treatment options. Stem cells, to be more specific, are multipotent cells that can be found in various parts of the body; they can be accessed and harvested through minimally invasive means and then processed to create an injectate. Autologous stem cells for use in the orthopedic setting are either adipocytes or mesenchymal, derived from fat tissue or bone marrow, respectively. The growing body of research has demonstrated favorable clinical outcomes, such as decreased pain and increased function, and as the research regarding stem cell therapies continues to grow, this could prove to be a safe and efficacious treatment option for those suffering from both acute and chronic pain and functional limitations.

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Author information

Authors and Affiliations

  1. Sports Medicine and Interventional Spine, Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Nadia N. Zaman & Dayna McCarthy

Authors
  1. Nadia N. Zaman
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  2. Dayna McCarthy
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Editor information

Editors and Affiliations

  1. Princeton Spine and Joint Center, Princeton, NJ, USA

    Grant Cooper

  2. Department of Rehabilitation Medicine, Mount Sinai Hospital, New York, NY, USA

    Joseph Herrera

  3. Princeton Spine and Joint Center, Princeton, NJ, USA

    Jason Kirkbride

  4. Princeton Spine and Joint Center, Princeton, NJ, USA

    Zachary Perlman

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Zaman, N.N., McCarthy, D. (2020). Stem Cells. In: Cooper, G., Herrera, J., Kirkbride, J., Perlman, Z. (eds) Regenerative Medicine for Spine and Joint Pain. Springer, Cham. https://doi.org/10.1007/978-3-030-42771-9_4

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  • DOI: https://doi.org/10.1007/978-3-030-42771-9_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-42770-2

  • Online ISBN: 978-3-030-42771-9

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