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Role of Nutraceuticals in Maternal Nutrition

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Functional Foods and Nutraceuticals

Abstract

Diet has an important impact on human health. Healthy diets, therefore, promote good health. The most recent scientific literature broadly supports the importance of diet-related habits during pregnancy and breastfeeding, in the same manner, lifestyle also affect the health of mothers and their offspring. Consumption from the preconceptional era of a diverse and balanced diet is essential for wellbeing as well as for the outcomes of pregnancy. However, micronutrient deficiencies due to inadequate intake and other forms, even in the most industrialized countries, during pregnancy and lactation may be due to inadequate intakes of specific micronutrients during pregnancy and lactation. This chapter presents the role of nutraceuticals in maternal nutrition.

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References

  • Agostoni C, Marangoni F, Grandi F, Lammardo AM, Giovannini M, Riva E, Galli C (2003) Earlier smoking habits are associated with higher serum lipids and lower milk fat and polyunsaturated fatty acid content in the first 6 months of lactation. Eur J Clin Nutr 57(11):1466–1472

    Article  CAS  PubMed  Google Scholar 

  • Agostoni C, Galli C, Riva E, Colombo C, Giovannini M, Marangoni F (2005) Reduced docosahexaenoic acid synthesis may contribute to growth restriction in infants born to mothers who smoke. J Pediatr 147(6):854–856

    Article  CAS  PubMed  Google Scholar 

  • Allen LH (2000) Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr 71(5):1280S–1284S

    Article  CAS  PubMed  Google Scholar 

  • Allen LH (2003) Interventions for micronutrient deficiency control in developing countries: past, present and future. J Nutr 133(11):3875S–3878S

    Article  CAS  PubMed  Google Scholar 

  • Allen LH (2005) Multiple micronutrients in pregnancy and lactation: an overview. Am J Clin Nutr 81(5):1206S–1212S

    Article  CAS  PubMed  Google Scholar 

  • Allen LH, Kerstetter JE (2005) Calcium. In: Allen L, Prentice A (eds) Encyclopedia of human nutrition, 2nd edn. Elsevier Ltd, Amsterdam, pp 253–259

    Chapter  Google Scholar 

  • Alwan NA, Cade JE, McArdle HJ, Greenwood DC, Hayes HE, Simpson NA (2015) Maternal iron status in early pregnancy and birth outcomes: insights from the baby’s vascular health and iron in pregnancy study. Br J Nutr 113(12):1985–1992

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Berger MM, Shenkin A (2006) Vitamins and trace elements: practical aspects of supplementation. Nutrition 22(9):952–955

    Article  CAS  PubMed  Google Scholar 

  • Berti C, Fekete K, Dullemeijer C, Trovato M, Souverein OW, Cavelaars A et al (2012) Folate intake and markers of folate status in women of reproductive age, pregnant and lactating women: a meta-analysis. J Nutr Metab 2012:1–13

    Article  CAS  Google Scholar 

  • Bhutta ZA, Haider BA (2009) Prenatal micronutrient supplementation: are we there yet? CMAJ 180(12):1188–1189

    Article  PubMed  PubMed Central  Google Scholar 

  • Bhutta ZA, Ahmed T, Black RE, Cousens S, Dewey K, Giugliani E et al (2008) What works? Interventions for maternal and child undernutrition and survival. Lancet 371(9610):417–440

    Article  PubMed  Google Scholar 

  • Bhutta ZA, Das JK, Rizvi A, Gaffey MF, Walker N, Horton S et al (2013) Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost? Lancet 382(9890):452–477

    Article  PubMed  Google Scholar 

  • Biesalski HK (2001) Nutraceuticals: the link between nutrition and medicine. Oxid Stress Dis 6:1–26

    CAS  Google Scholar 

  • Brenna JT, Salem N Jr, Sinclair AJ, Cunnane SC, International Society for the Study of Fatty Acids and Lipids, ISSFAL (2009) Alpha-linolenic acid supplementation and conversion to n-3 long-chain polyunsaturated fatty acids in humans. Prostaglandins Leukot Essent Fat Acids 80(2–3):85–91

    Article  CAS  Google Scholar 

  • Bruce KD (2014) Maternal and in utero determinants of type 2 diabetes risk in the young. Curr Diab Rep 14(1):446

    Article  PubMed  CAS  Google Scholar 

  • Cashman KD, Kiely M (2014) Recommended dietary intakes for vitamin D: where do they come from, what do they achieve and how can we meet them? J Hum Nutr Diet 27(5):434–442

    Article  CAS  PubMed  Google Scholar 

  • Catalano P, Demouzon SH (2015) Maternal obesity and metabolic risk to the offspring: why lifestyle interventions may have not achieved the desired outcomes. Int J Obes 39(4):642–649

    Article  CAS  Google Scholar 

  • Cawley S, Mullaney L, McKeating A, Farren M, McCartney D, Turner MJ (2016) A review of European guidelines on periconceptional folic acid supplementation. Eur J Clin Nutr 70(2):143–154

    Article  CAS  PubMed  Google Scholar 

  • Cetin I, Laoreti A (2015) The importance of maternal nutrition for health. In: From the womb to the adult: international workshop on neonatology and satellite meetings, October 26–31, vol 4, no 2, pp 1–11. Hygeia Press

    Google Scholar 

  • Cetin I, Berti C, Mandò C, Parisi F (2011) Placental iron transport and maternal absorption. Ann Nutr Metab 59(1):55–58

    Article  CAS  PubMed  Google Scholar 

  • Clapp JF III (2002) Maternal carbohydrate intake and pregnancy outcome. Proc Nutr Soc 61(1):45–50

    Article  PubMed  Google Scholar 

  • Cohen GR, Curet LB, Levine RJ, Ewell MG, Morris CD, Catalano PM et al (2001) Ethnicity, nutrition, and birth outcomes in nulliparous women. Am J Obstet Gynecol 185(3):660–667

    Article  CAS  PubMed  Google Scholar 

  • Cox JT, Phelan ST (2009) Prenatal nutrition: special considerations. Minerva Ginecol 61(5):373–400

    CAS  PubMed  Google Scholar 

  • Danaei G, Ding EL, Mozaffarian D, Taylor B, Rehm J, Murray CJ, Ezzati M (2009) The preventable causes of death in the United States: comparative risk assessment of dietary, lifestyle, and metabolic risk factors. PLoS Med 6(4):e1000058

    Article  PubMed  PubMed Central  Google Scholar 

  • De-Regil LM, Palacios C, Lombardo LK, Peña-Rosas JP (2016) Vitamin D supplementation for women during pregnancy. Cochrane Database Syst Rev 1:CD008873

    Google Scholar 

  • EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies) (2014) Scientific opinion on dietary reference values for folate. EFSA J 12:3893–3951

    Google Scholar 

  • EFSA Scientific Committee (2015) Statement on the benefits of fish/seafood consumption compared to the risks of methylmercury in fish/seafood. EFSA J 13(1):3982

    Article  CAS  Google Scholar 

  • El-Bastawissi AY, Peters R, Sasseen K, Bell T, Manolopoulos R (2007) Effect of the Washington special supplemental nutrition program for women, infants and children (WIC) on pregnancy outcomes. Matern Child Health J 11(6):611–621

    Article  PubMed  Google Scholar 

  • Eussen S, Alles M, Uijterschout L, Brus F, Van Der Horst-graat J (2015) Iron intake and status of children aged 6-36 months in Europe: a systematic review. Ann Nutr Metab 66(2–3):80–92

    Article  CAS  PubMed  Google Scholar 

  • Fall CH, Yajnik CS, Rao S, Davies AA, Brown N, Farrant HJ (2003) Micronutrients and fetal growth. J Nutr 133(5):1747S–1756S

    Article  CAS  PubMed  Google Scholar 

  • Fekete K, Berti C, Trovato M, Lohner S, Dullemeijer C, Souverein OW et al (2012) Effect of folate intake on health outcomes in pregnancy: a systematic review and meta-analysis on birth weight, placental weight and length of gestation. Nutr J 11(1):75

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Food and Agriculture Organization of the United Nations (Rome) (2013) Dietary protein quality evaluation in human nutrition: report of an FAO expert consultation, 31 March–2 April, 2011, Auckland, New Zealand. Food and Agriculture Organization of the United Nations

    Google Scholar 

  • Freisling H, Fahey MT, Moskal A, Ocké MC, Ferrari P, Jenab M et al (2010) Region-specific nutrient intake patterns exhibit a geographical gradient within and between European countries. J Nutr 140(7):1280–1286

    Article  CAS  PubMed  Google Scholar 

  • Haider BA, Bhutta ZA (2017) Multiple-micronutrient supplementation for women during pregnancy. Cochrane Database Syst Rev 4:CD004905

    PubMed  Google Scholar 

  • Hoey L, McNulty H, Duffy ME, Hughes CF, Strain JJ (2013) EURRECA – estimating folate requirements for deriving dietary reference values. Crit Rev Food Sci Nutr 53(10):1041–1050

    Article  CAS  PubMed  Google Scholar 

  • Hofmeyr GJ, Lawrie TA, Atallah ÁN, Duley L, Torloni MR (2014) Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems. Cochrane Database Syst Rev 6:CD001059

    Google Scholar 

  • Istituto Superiore di Sanità (2016) Monitoring of the nationwide program of iodine prophylaxis in Italy. Available online: http://www.iss.it/binary/publ/cont/14_6_web.pdf. Accessed on 2 May 2016

  • Khambalia AZ, Collins CE, Roberts CL, Morris JM, Powell KL, Tasevski V, Nassar N (2016) Iron deficiency in early pregnancy using serum ferritin and soluble transferrin receptor concentrations are associated with pregnancy and birth outcomes. Eur J Clin Nutr 70(3):358–363

    Article  CAS  PubMed  Google Scholar 

  • Klaffke W (2007) Functional food – natural substance research for healthy eating, natural products research in Germany. Vorbild Natur, pp 90–97

    Google Scholar 

  • Koletzko B, Cetin I, Brenna JT, Perinatal Lipid Intake Working Group (2007) Dietary fat intakes for pregnant and lactating women. Br J Nutr 98(5):873–877

    Article  CAS  PubMed  Google Scholar 

  • Koletzko B, Agostoni C, Bergmann R, Ritzenthaler K, Shamir R (2011) Physiological aspects of human milk lipids and implications for infant feeding: a workshop report. Acta Paediatr 100(11):1405–1415

    Article  CAS  PubMed  Google Scholar 

  • Koletzko B, Bauer CP, Bung P, Cremer M, Flothkötter M, Hellmers C et al (2013) German national consensus recommendations on nutrition and lifestyle in pregnancy by the ‘healthy start-young family network’. Ann Nutr Metab 63(4):311–322

    Article  CAS  PubMed  Google Scholar 

  • Kramer MS, Kakuma R (2003) Energy and protein intake in pregnancy. Cochrane Database Syst Rev 4:CD000032

    Google Scholar 

  • Krebs NF, Domellöf M, Ziegler E (2015) Balancing benefits and risks of iron fortification in resource-rich countries. J Pediatr 167(4):S20–S25

    Article  PubMed  Google Scholar 

  • Lamberg-Allardt C, Ala-Houhala M, Ahola M, Parviainen MT, Räsänen L, Visakorpi J (1986) Vitamin D status of children and adolescents in Finland. Ann Nutr Metab 30(4):267–272

    Article  CAS  PubMed  Google Scholar 

  • Lombardi-Boccia G, Aguzzi A, Cappelloni M, Di Lullo G, Lucarini M (2003) Total-diet study: dietary intakes of macro elements and trace elements in Italy. Br J Nutr 90(6):1117–1121

    Article  CAS  PubMed  Google Scholar 

  • Loy SL, Marhazlina M, Nor Azwany Y, Hamid Jan JM (2011) Higher intake of fruits and vegetables in pregnancy is associated with birth size. Southeast Asian J Trop Med Public Health 42(5):1214

    PubMed  Google Scholar 

  • Marangoni F, Cetin I, Verduci E, Canzone G, Giovannini M, Scollo P et al (2016) Maternal diet and nutrient requirements in pregnancy and breastfeeding. An Italian consensus document. Nutrients 8(10):629

    Article  PubMed Central  CAS  Google Scholar 

  • Mennitti LV, Oliveira JL, Morais CA, Estadella D, Oyama LM, do Nascimento CMO, Pisani LP (2015) Type of fatty acids in maternal diets during pregnancy and/or lactation and metabolic consequences of the offspring. J Nutr Biochem 26(2):99–111

    Article  CAS  PubMed  Google Scholar 

  • Merialdi M, Carroli G, Villar J, Abalos E, Gulmezoglu AM, Kulier R, de Onis M (2003) Nutritional interventions during pregnancy for the prevention or treatment of impaired fetal growth: an overview of randomized controlled trials. J Nutr 133(5):1626S–1631S

    Article  CAS  PubMed  Google Scholar 

  • Mozaffarian D, Rimm EB (2006) Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA 296(15):1885–1899

    Article  CAS  PubMed  Google Scholar 

  • Novaković R, Cavelaars AE, Bekkering GE, Roman-Vinas B, Ngo J, Gurinović M et al (2013) Micronutrient intake and status in Central and Eastern Europe compared with other European countries, results from the EURRECA network. Public Health Nutr 16(5):824–840

    Article  PubMed  Google Scholar 

  • O’Connor DL, Green T, Picciano MF (1997) Maternal folate status and lactation. J Mammary Gland Biol Neoplasia 2(3):279–289

    Article  PubMed  Google Scholar 

  • Olausson H, Goldberg GR, Laskey MA, Schoenmakers I, Jarjou LM, Prentice A (2012) Calcium economy in human pregnancy and lactation. Nutr Res Rev 25(1):40–67

    Article  CAS  PubMed  Google Scholar 

  • Pastorelli AA, Stacchini P, Olivieri A (2015) Daily iodine intake and the impact of salt reduction on iodine prophylaxis in the Italian population. Eur J Clin Nutr 69(2):211–215

    Article  CAS  PubMed  Google Scholar 

  • Peña-Rosas JP, Viteri FE (2009) Effects and safety of preventive oral iron or iron+ folic acid supplementation for women during pregnancy. Cochrane Database Syst Rev 4:CD004736

    Google Scholar 

  • Pounis G, de Lorgeril M, Salen P, Laporte F, Krogh V, Siani A et al (2014) Dietary patterns and fatty acids levels of three European populations. Results from the IMMIDIET study. Nutr Metab Cardiovasc Dis 24(8):883–890

    Article  CAS  PubMed  Google Scholar 

  • Pushpangadan P, Dan VM, Ijinu TP, George V (2012) Food, nutrition and beverage. Indian J Tradit Knowl 11(1):26–34

    Google Scholar 

  • Pushpangadan P, George V, Sreedevi P, Bincy AJ, Anzar S, Aswany T et al (2014) Functional foods and nutraceuticals with special focus on mother and child care. Ann Phytomed 3(1):4–24

    CAS  Google Scholar 

  • Ramaa CS, Shirode AR, Mundada AS, Kadam VJ (2006) Nutraceuticals-an emerging era in the treatment and prevention of cardiovascular diseases. Curr Pharm Biotechnol 7(1):15–23

    Article  CAS  PubMed  Google Scholar 

  • Ross S (2000) Functional foods: the Food and Drug Administration perspective. Am J Clin Nutr 71(6):1735S–1738S

    Article  CAS  PubMed  Google Scholar 

  • Sallis H, Steer C, Paternoster L, Smith GD, Evans J (2014) Perinatal depression and omega-3 fatty acids: a Mendelian randomisation study. J Affect Disord 166:124–131

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sauerwald TU, Demmelmair H, Koletzko B (2001) Polyunsaturated fatty acid supply with human milk. Lipids 36(9):991–996

    Article  CAS  PubMed  Google Scholar 

  • Schaafsma G (2000) The protein digestibility–corrected amino acid score. J Nutr 130(7):1865S–1867S

    Article  CAS  PubMed  Google Scholar 

  • Shah PS, Ohlsson A (2009) Knowledge synthesis group on determinants of low birth weight and preterm births. Effects of prenatal multimicronutrient supplementation on pregnancy outcomes: a meta-analysis. CMAJ 180(12):E99–E108

    Article  PubMed  PubMed Central  Google Scholar 

  • Siu AL (2015) Screening for iron deficiency anemia and iron supplementation in pregnant women to improve maternal health and birth outcomes: US Preventive Services Task Force recommendation statement. Ann Intern Med 163(7):529–536

    Article  PubMed  Google Scholar 

  • Società di Nutrizione Umana (SINU) (2014) LARN – Livelli di Assunzione di Riferimento di Nutrienti ed Energia per la Popolazione Italiana; IV Revisione; SICS: Milano, Italy, pp 1–655

    Google Scholar 

  • Spiro A, Buttriss JL (2014) Vitamin D: an overview of vitamin D status and intake in E urope. Nutr Bull 39(4):322–350

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F et al (2013) Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: a systematic analysis of population-representative data. Lancet Glob Health 1(1):e16–e25

    Article  PubMed  PubMed Central  Google Scholar 

  • Tan J, Loganath A, Chong YS et al (2009) Exposure to persistent organic pollutants in utero and related maternal characteristics on birth outcomes: a multivariate data analysis approach. Chemosphere 74(3):428–433

    Article  CAS  PubMed  Google Scholar 

  • Tetens I (2014) EFSA NDA panel (EFSA panel on panel on dietetic products nutrition and allergies), 2014. Scientific Opinion on Dietary Reference Values for iodine

    Google Scholar 

  • Theobald HE (2005) Dietary calcium and health. Nutr Bull 30(3):237–277

    Article  Google Scholar 

  • Trumbo P, Schlicker S, Yates AA, Poos M (2002) Dietary reference intakes for energy, carbohdrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Acad Nutr Diet 102(11):1621

    Google Scholar 

  • Trumpff C, Vandevijvere S, Moreno-Reyes R, Vanderpas J, Tafforeau J, Van Oyen H, De Schepper J (2015) Neonatal thyroid-stimulating hormone level is influenced by neonatal, maternal, and pregnancy factors. Nutr Res 35(11):975–981

    Article  CAS  PubMed  Google Scholar 

  • US Preventive Services Task Force (2009) Folic acid for the prevention of neural tube defects: US Preventive Services Task Force recommendation statement. Ann Intern Med 150(9):626

    Article  Google Scholar 

  • WHO (2014). Available: http://www.who.int/topics/nutrition/en/. Accessed on 28 May 2014

  • WHO/UNICEF (2016) Reaching optimal iodine nutrition in pregnant and lactating women and young children. Available online: http://www.who.int/nutrition/publications/WHOStatement__IDD_pregnancy.pdf. Accessed on 4 June 2016

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Authors and Affiliations

  1. Institute of Home and Food Sciences, Faculty of Life Sciences, Government College University, Faisalabad, Pakistan

    Sadia Hassan & Neelam Faiza

  2. Institute of Food Science and Nutrition, University of Sargodha, Sargodha, Pakistan

    Muhammad Adil Farooq &  Habib-ur-Rehman

  3. Department of Biochemistry, Faculty of Natural Sciences, Chukwuemeka Odumegwu Ojukwu University, Uli, Anambra State, Nigeria

    Chukwuebuka Egbuna

  4. Department of Biochemistry, Abubakar Tafawa Balewa University, Bauchi, Nigeria

    Ahmed Olatunde

Authors
  1. Sadia Hassan
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  2. Neelam Faiza
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  3. Muhammad Adil Farooq
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  4. Chukwuebuka Egbuna
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  5. Habib-ur-Rehman
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  6. Ahmed Olatunde
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Editors and Affiliations

  1. Department of Biochemistry, Chukwuemeka Odumegwu Ojukwu University, Uli, Nigeria

    Chukwuebuka Egbuna

  2. College of Medicine, Davao Medical School Foundation, Inc., Davao City, Philippines

    Genevieve Dable Tupas

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Hassan, S., Faiza, N., Farooq, M.A., Egbuna, C., Habib-ur-Rehman, Olatunde, A. (2020). Role of Nutraceuticals in Maternal Nutrition. In: Egbuna, C., Dable Tupas, G. (eds) Functional Foods and Nutraceuticals. Springer, Cham. https://doi.org/10.1007/978-3-030-42319-3_24

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