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Caring for Transgender and Gender Diverse Youth with Co-occurring Neurodiversity

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Pediatric Gender Identity

Abstract

Research points to an association between gender diversity and the clinical characteristics of autism spectrum disorder (ASD)/neurodiversity, and it has been suggested that gender dysphoria (GD) and ASD intersect more frequently than would be estimated by chance. Several hypotheses have been forwarded to explain this potential co-occurrence, but empirical evidence for these hypotheses is lacking. Co-occurring ASD might come with specific challenges in assessment of individuals with gender identity questions. However, there is a clinical consensus that GD and ASD can co-occur independently, and that an ASD diagnosis should not be an exclusion criterion for a GD diagnosis in children and adolescents, nor for gender-affirming medical treatment in adolescents. While exploring gender identity in youth with ASD, it is important to take ASD-specific challenges into account and to adjust the assessment process to their needs. With respect to gender affirmative interventions, a carefully evaluated stepwise approach that takes into account specific ASD characteristics is indicated.

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References

  1. Ristori J, Steensma TD. Gender dysphoria in childhood. Int Rev Psychiatry. 2016;28:13–20.

    Article  PubMed  Google Scholar 

  2. Leibowitz SF, de Vries ALC. Gender dysphoria in adolescence. Int Rev Psychiatry. 2016;28:21–35.

    Article  PubMed  Google Scholar 

  3. Mukaddes NM. Gender identity problems in autistic children. Child Care Health Dev. 2002;28:529–32.

    Article  CAS  PubMed  Google Scholar 

  4. de Vries ALC, Noens ILJ, Cohen-Kettenis PT, van Berckelaer-Onnes IA, Doreleijers TAH. Autism spectrum disorders in gender dysphoric children and adolescents. J Autism Dev Disord. 2010;40:930–6.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Øien RA, Cicchetti DV, Nordahl-Hansen A. Gender dysphoria, sexuality and autism spectrum disorders: a systematic review. J Autism Dev Disord. 2018;48:4028–37.

    Article  PubMed  Google Scholar 

  6. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Publishing; 2013.

    Book  Google Scholar 

  7. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed., Text Revision ed. Washington, DC: American Psychiatric Publishing; 2000.

    Google Scholar 

  8. Lai M-C, Lombardo MV, Baron-Cohen S. Autism. Lancet. 2014;383:896–910.

    Article  PubMed  Google Scholar 

  9. Park HR, Lee JM, Moon HE, Lee DS, Kim BN, Kim J, et al. A short review on the current understanding of autism spectrum disorders. Exp Neurobiol. 2016;25:1–13.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Baron-Cohen S. Editorial perspective: neurodiversity – a revolutionary concept for autism and psychiatry. J Child Psychol Psychiatry. 2017;58:744–7.

    Article  PubMed  Google Scholar 

  11. Tateno M, Tateno Y, Saito Y. Comorbid childhood gender identity disorder in a boy with Asperger syndrome. Psychiatry Clin Neurosci. 2008;62:238.

    Article  PubMed  Google Scholar 

  12. Wing L. Diagnostic interview for social and communication disorders. Manual. Bromley: Centre for social and communication disorders; 1999.

    Google Scholar 

  13. Akgül GY, Ayaz AB, Yildirim G, Fis NP. Autistic traits and executive functions in children and adolescents with gender dysphoria. J Sex Marital Ther. 2018;44:619–26.

    Article  PubMed  Google Scholar 

  14. Di Ceglie D, Skagerberg E, Baron-Cohen S, Auyeung B. Empathising and systemising in adolescents with gender dysphoria. Opticion 1826. 2014;16:1–8.

    Google Scholar 

  15. Skagerberg E, Di Ceglie D, Carmichael P. Brief report: autistic features in children and adolescents with gender dysphoria. J Autism Dev Disord. 2015;45:2628–32.

    Article  PubMed  Google Scholar 

  16. VanderLaan DP, Postema L, Wood H, Singh D, Fantus S, Hyun J, et al. Do children with gender dysphoria have intense/obsessional interests? J Sex Res. 2014;52:213–9.

    Article  PubMed  Google Scholar 

  17. VanderLaan DP, Leef JH, Wood H, Hughes SK, Zucker KJ. Autism spectrum disorder risk factors and autistic traits in gender dysphoric children. J Autism Dev Disord. 2015;46:1742–50.

    Article  Google Scholar 

  18. Shumer DE, Reisner SL, Edwards-Leeper L, Tishelman A. Evaluation of Asperger syndrome in youth presenting to a gender dysphoria clinic. LGBT Health. 2016;3:387–90.

    Article  PubMed  PubMed Central  Google Scholar 

  19. van der Miesen AIR, de Vries ALC, Steensma TD, Hartman CA. Autistic symptoms in children and adolescents with gender dysphoria. J Autism Dev Disord. 2018;48:1537–48.

    Article  PubMed  Google Scholar 

  20. Turban JL, van Schalkwyk GI. “Gender dysphoria” and autism spectrum disorder: is the link real? J Am Acad Child Adolesc Psychiatry. 2018;57:8–9.e2.

    Article  PubMed  Google Scholar 

  21. Hisle-Gorman E, Landis CA, Susi A, Schvey NA, Gorman GH, Nylund CM, et al. Gender dysphoria in children with autism spectrum disorder. LGBT Health. 2019;6:95–100.

    Article  PubMed  Google Scholar 

  22. Janssen A, Huang H, Duncan C. Gender variance among youth with autism spectrum disorders: a retrospective chart review. Transgend Health. 2016;1:63–8.

    Article  PubMed  PubMed Central  Google Scholar 

  23. May T, Pang K, Williams KJ. Gender variance in children and adolescents with autism spectrum disorders from the National Database for Autism Research. Int J Transgend. 2017;18:1–9.

    Article  Google Scholar 

  24. Strang JF, Kenworthy L, Dominska A, Sokoloff J, Kenealy LE, Berl M, et al. Increased gender variance in autism spectrum disorders and attention deficit hyperactivity disorder. Arch Sex Behav. 2014;43:1525–33.

    Article  PubMed  Google Scholar 

  25. van der Miesen AIR, Hurley H, Bal AM, de Vries ALC. Prevalence of the wish to be of the opposite gender in adolescents and adults with autism spectrum disorder. Arch Sex Behav. 2018;47:2307–17.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Nabbijohn AN, van der Miesen AIR, Santarossa A, Peragine D, de Vries ALC, Popma A, et al. Gender variance and the autism spectrum: an examination of children ages 6–12 years. J Autism Dev Disord. 2019;49:1570–85.

    Article  PubMed  Google Scholar 

  27. van der Miesen AIR, Hurley H, de Vries ALC. Gender dysphoria and autism spectrum disorder: a narrative review. Int Rev Psychiatry. 2016;28:70–80.

    Article  Google Scholar 

  28. Greenberg DM, Warrier V, Allison C, Baron-Cohen S. Testing the empathizing-systemizing theory of sex differences and the extreme male brain theory of autism in half a million people. PNAS. 2018;115:12152–7.

    Article  CAS  PubMed  Google Scholar 

  29. Baron-Cohen S. The extreme male brain theory of autism. Trends Cogn Sci. 2002;6:248–54.

    Article  PubMed  Google Scholar 

  30. Hines M, Constantinescu M, Spencer D. Early androgen exposure and human gender development. Biol Sex Differ. 2015;6:3.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  31. Jones RM, Weelwright S, Farrel K, Martin E, Green R, Di Ceglie D. Brief report: female-to-male transsexual people and autistic traits. J Autism Dev Disord. 2012;42:301–6.

    Article  PubMed  Google Scholar 

  32. Parkinson J. Gender dysphoria in Asperger’s syndrome: a caution. Australas Psychiatry. 2014;22:84–5.

    Article  PubMed  Google Scholar 

  33. Williams P, Allard AM, Sears L. Case study: cross-gender preoccupations in two male children with autism. J Autism Dev Disord. 1996;26:635–42.

    Article  CAS  PubMed  Google Scholar 

  34. Ehrensaft D. Double helix rainbow kids. J Autism Dev Disord. 2018;48:4079–81.

    Article  PubMed  Google Scholar 

  35. Walsh RJ, Krabbendam L, Dewinter J, Begeer S. Brief report: gender identity differences in autistic adults: associations with perceptual and socio-cognitive profiles. J Autism Dev Disord. 2018;48:4070–80.

    Article  PubMed  Google Scholar 

  36. Cooper K, Smith LGE, Russel AJ. Gender identity in autism: sex differences in social affiliation with gender groups. J Autism Dev Disord. 2018;48:3995–4006.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Strang JF, Meagher H, Kenworthy L, de Vries ALC, Menvielle E, Leibowitz SF, et al. Initial guidelines for co-occurring autism spectrum disorder and gender dysphoria or incongruence in adolescents. J Clin Child Adolesc Psychol. 2018;47:105–15.

    Article  PubMed  Google Scholar 

  38. Coleman E, Bockting W, Botzer M, Cohen-Kettenis PT, DeCuypere G, Feldman J, et al. Standards of care for the health of transsexual, transgender and gender non-conforming people, version 7. Int J Transgend. 2011;13:165–232.

    Article  Google Scholar 

  39. Strang JF, Powers MD, Knauss M, Sibarium E, Leibowitz SF, Kenworthy L, et al. “They thought it was an obsession”: trajectories and perspectives of autistic transgender and gender-diverse adolescents. J Autism Dev Disord. 2018;48:4039–55.

    Article  PubMed  Google Scholar 

  40. de Vries ALC, Cohen-Kettenis PT. Clinical management of gender dysphoria in children and adolescents: the Dutch approach. J Homosex. 2012;59:301–20.

    Article  PubMed  Google Scholar 

  41. Schagen SEE, Cohen-Kettenis PT, Delemarre-van de Waal HA, Hannema SE. Efficacy and safety of gonadotropin-releasing hormone agonist treatment to suppress puberty in gender dysphoric adolescents. J Sex Med. 2016;17:1125–32.

    Article  Google Scholar 

  42. Mahfouda S, Moore JK, Siafarikas A, Hewit T, Ganti U, Lin A, et al. Gender-affirming hormones and surgery in transgender children and adolescents. Lancet Diabetes Endocrinol. 2019;7:484–98.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgment

The authors thank A. Natisha Nabbijohn for the helpful contribution during the draft of the manuscript.

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This chapter received no specific grant from any funding agency or commercial or not-for-profit sectors.

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The authors declare that they have no conflict of interest.

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Correspondence to Roy H. T. van Vlerken .

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van Vlerken, R.H.T., Fuchs, C.E., van der Miesen, A.I.R. (2020). Caring for Transgender and Gender Diverse Youth with Co-occurring Neurodiversity. In: Forcier, M., Van Schalkwyk, G., Turban, J. (eds) Pediatric Gender Identity. Springer, Cham. https://doi.org/10.1007/978-3-030-38909-3_10

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  • DOI: https://doi.org/10.1007/978-3-030-38909-3_10

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