Abstract
Diabetes is a long-term metabolic disorder that is characterized by high blood glucose, insulin resistance, and relative lack of insulin. The inclusion of dietary fiber helps controls glucose and insulin levels and favorably influences plasma lipid levels in patients with type 2 diabetes. Soluble fiber is characterized by its ability to dissolve in water and form viscous gels, which allows the intestinal transit time to decrease and delay absorption and complete digestion of nutrients, related to the decrease of postprandial glucose peaks, reduction of insulin and serum lipid levels. Some of the main types of soluble fiber are: β-glucans, inulin, fructoligosaccharides, arabinoxylans and pectins. The consumption of insoluble fiber can act as a physical barrier so it could reduce the speed of digestive products through the brush border of the enterocyte. One of the mechanisms of action for dietary fiber and prebiotics is fermentation in the colon and changes in the intestinal microbiota. Prebiotics are non-digestible food ingredients that selectively stimulate the growth and/or activity of a limited number of colonic bacteria and, subsequently, improve the health of the host. The general recommendation of fiber intake in patients with type 2 diabetes is 20–35 g/day.
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References
Alberti KG (1995) Local research ethics committees. BMJ 311(7006):639–640
American Diabetes Association Standards of Medical Care in Diabetes (2016) Classification and diagnosis of diabetes. Diabetes Care 39(Supplement 1):S13–S22
Anderson JW (1995) Dietary fibre, complex carbohydrate and coronary artery disease. Can J Cardiol (11 Suppl G):55G–62G
Asp NG (1987) Dietary fibre: definition, chemistry and analytical determination. Mol Asp Med 9:17–29
Barsanti L, Passarelli V, Evangelista V, Frassanito AM, Gualtieri P (2011) Chemistry, physico-chemistry and applications linked to biological activities of beta-glucans. Nat Prod Rep 28(3):457–466
Belobrajdi DP, Bird AR (2013) The potential role of phytochemicals in wholegrain cereals for the prevention of type-2 diabetes. Nutr J 12:62
Bodinham CL, Al-Mana NM, Smith L, Robertson MD (2013) Endogenous plasma glucagon-like peptide-1 following acute dietary fibre consumption. Br J Nutr 110(8):1429–1433
Bodinham CL, Smith L, Thomas EL, Bell JD, Swann JR, Costabile A, Rusell-Jones D, Umpleby M, Robertson MD (2014) Efficacy of increased resistant starch consumption in human type 2 diabetes. Endocr Connect 3(2):75–84
Brown L, Rosner B, Willett WW, Sacks FM (1999) Cholesterol-lowering effects of dietary fiber: a meta-analysis. Am J Clin Nutr 69(1):30–42
Chamberlain JJ, Rhinehart AS, Shaefer CF Jr, Neuman A (2016) Diagnosis and management of diabetes: synopsis of the 2016 American Diabetes Association standards of medical Care in Diabetes. Ann Intern Med 164(8):542–552
Champ M, Langkilde AM, Brouns F, Kettlitz B, Bail-Collet YL (2003) Advances in dietary fibre characterisation. 1. Definition of dietary fibre, physiological relevance, health benefits and analytical aspects. Nutr Res Rev 16(2):71–82
Chen J, Kenneth R (2008) β-Glucans in the treatment of diabetes and associated cardiovascular risks. Vasc Health Risk Manag 4(6):1265–1272
Chen J, Seviour R (2007) Medicinal importance of fungal β-(1→3), (1→6)-glucans. Mycol Res 111(Pt 6):635–652
Cheng HH, Lai MH (2000) Fermentation of resistant rice starch produces propionate reducing serum and hepatic cholesterol in rats. J Nutr 130(8):1991–1995
Cluny NL, Eller LK, Keenan CM, Reimer RA, Sharkey KA (2015a) Interactive effects of oligofructose and obesity predisposition on gut hormones and microbiota in diet-induced obese rats. Obesity 23(4):769–778
Cluny NL, Keenan CM, Reimer RA, Le Foll B, Sharkey KA (2015b) Prevention of diet-induced obesity effects on body weight and gut microbiota in mice treated chronically with delta9-tetrahydrocannabinol. PLoS One 10(12):e0144270
Creely SJ, McTernan PG, Kusminski CM, Fisher FM, Da Silva NF, Khanolkar M, Evans M, Harte AL, Kumar S (2007) Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab 292(3):740–747
Crittenden R, Karppinen S, Ojanen S, Tenkanen M, Fagerstorm R, Matto J (2002) In vitro fermentation of cereal dietary fibre carbohydrates by probiotic and intestinal bacteria. J Sci Food Agric 82(8):781–789
Davison KM, Temple NJ (2018) Cereal fiber, fruit fiber, and type 2 diabetes: explaining the paradox. J Diabetes Complicat 32:240–245
Dehghan P, Gargari BP, Jafar-Abadi MA (2014) Oligofructose-enriched inulin improves some inflammatory markers and metabolic endotoxemia in women with type 2 diabetes mellitus: a randomized controlled clinical trial. Nutrition 30(4):418–423
Delzenne NM, Kok N (2001) Effects of fructans-type prebiotics on lipid metabolism. Am J Clin Nutr 73(2 Suppl):456S–458S
Delzenne NM, Neyrinck AM, Cani PD (2011) Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome. Microb Cell Factories 10(Suppl 1):S10
Derrien M, Vaughan EE, Plugge CM, De Vos WM (2004) Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium. Internal. J Syst Evol Microbiol 54(Pt 5):1469–1476
Dhingra D, Michael M, Rajput H, Patil RT (2012) Dietary fibre in foods: a review. J Food Sci Technol 49(3):255–266
El Khoury D, Cuda C, Luhovyy BL, Anderson GH (2012) Beta glucan: health benefits in obesity and metabolic syndrome. J Nutr Metab 2012.: 851362:1–28
Esser N, Legrand-Poels S, Piette J, Scheen AJ, Paquot N (2014) Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes. Diabetes Res Clin Pract 105(2):141–150
Everard A, Lazarevic V, Derrien M, Girard M, Muccioli GG, Neyrinck AM, Possemiers S, Van Holle A, François P, de Vos WM, Delzenne NM, Schrenzel J, Cani PD (2011) Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes 60(11):2775–2786
Farrer M, Fulcer G, Albers CJ, Neil HAW, Adams PC, Alberti KGMM (1995) Patients undergoing coronary artery bypass graft surgery are at high risk of impaired glucose tolerance and diabetes mellitus during the first postoperative year. Metabolism 44(8):1016–1027
Frost GS, Brynes AE, Dhillo WS, Bloom SR, McBurney MI (2003) The effects of fiber enrichment of pasta and fat content on gastric emptying, GLP-1, glucose, and insulin responses to a meal. Eur J Clin Nutr 57(2):293–298
Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Doré J, Henegar C, Rizkalla S, Clément K (2010) Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers. Diabetes 59(12):3049–3057
Gatenby SJ, Ellis PR, Morgan LM, Judd PA (1996) Effect of partially depolymerized guar gum on acute metabolic variables in patients with non-insulin-dependent diabetes. Diabet Med 13(4):358–364
Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, Kitzmiller J, Knowler WC, Lebovitz H, Lernmark A, Nathan D, Palmer J, Rizza R, Saudek C, Shaw J, Steffes M, Stern M, Tuomilehto J, Zimmet P (2003) Expert committee on the diagnosis and classification of diabetes mellitus 2003. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26(11):3160–3167
Gibson GR, Roberfroid MB (1995) Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 125(6):1401–1412
Gibson GR, Probert HM, Loo JV, Rastall RA, Roberfroid MB (2004) Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 17(2):259–275
Giugliano D, Maiorino MI, Bellastella G, Esposit K (2016) Comment on American diabetes association. Approaches to glycemic treatment. Sec. 7. In standards of medical care in diabetes-2016. Diabetes Care 39(Suppl. 1):S52–S59
Giulia Falchi A, Grecchi I, Muggia C, Palladini G, Perlini S (2016) Effects of a bioavailable arabinoxylan-enriched white bread flour on postprandial glucose response in normoglycemic subjects. J Diet Suppl 13(6):626–633
Griffith P (2004) The origins of an important cactus crop, Opuntia ficus-indica (cactacea): new molecular evidence. Am J Bot 91(11):1915–1921
Group IDFDA (2015) Update of mortality attributable to diabetes for the IDF diabetes atlas: estimates for the year 2013. Diabetes Res Clin Pract 109(3):461–465
Guess ND, Dornhorst A, Oliver N, Frost GS (2016) A randomised crossover trial: the effect of inulin on glucose homeostasis in subtypes of prediabetes. Ann Nutr Metab 68:26–34
Halliwell B, Gutteridge JMC (2007) Free radicals in biology & medicine, 5th edn. Oxford University Press, Oxford
Hipsley EH (1953) Dietary “fibre” and pregnancy toxaemia. Br Med J 2(4833):420–422
Honsek C, Kabisch S, Kemper M, Gerbracht C, Arafat AM, Birkenfeld AL, Dambeck U, Osterhoff MA, Weickert MO, Pfeiffe AFH (2018) Fibre supplementation for the prevention of type 2 diabetes and improvement of glucose metabolism: the randomised controlled Optimal Fibre Trial (OptiFiT). Diabetologia 61(6):1295–1305
Hossen MS, Ali MY, Jahurul MHA, Abdel-Daim MM, Gan SH, Khalil MI (2017) Beneficial roles of honey polyphenols against some human degenerative diseases: a review. Pharmacol Rep 69(6):1194–1205
Hsu MJ, Lee SS, Lin WW (2002) Polysaccharide purified from Ganoderma lucidum inhibits spontaneous and Fas-mediated apoptosis in human neutrophils through activation of the phosphatidylinositol 3 kinase/Akt signaling pathway. J Leukoc Biol 72(1):207–216
Jenkins DJA, Leeds AR, Gassull MA, Cochet B, Alberti KGMM (1977) Decrease in postprandial insulin and glucose concentrations by guar and pectin. Ann Intern Med 86:20–23
Jenkins AL, Jenkins DJ, Zdravkovic U, Würsch P, Vuksan V (2002a) Depression of the glycemic index by high levels of beta-glucan fiber in two functional foods tested in type 2 diabetes. Eur J Clin Nutr 56(7):622–628
Jenkins DJ, Kendall CW, Augustin LS, Franceschi S, Hamidi M, Marchie A, Jenkins AL, Axelsen M (2002b) Glycemic index: overview of implications in health and disease. Am J Clin Nutr 76(1):266S–273S
Joo E, Muraoka A, Hamasaki A, Harada N, Yamane S, Kondo Y, Suzuki K, Nasteska D, Shibue K, Harada T, Iwasaki K, Tsuji H, Shide K, Inagaki N (2015) Enteral supplementation with glutamine, fiber, and oligosaccharide modulates incretin and glucagon-like peptide-2 secretion. J Diabetes Investig 6(3):302–308
Kahn SE, Cooper ME, Del Prato S (2014) Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. Lancet 383(9922):1068–1083
Kapur NK, Ashen D, Blumenthal RS (2008) High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease. Vasc Health Risk Manag 4(1):39–57
Kiho T, Morimoto H, Sakushima M, Usui S, Ukai S (1995) Polysaccharides in fungi XXXV. Anti diabetic activity of an acidic polysaccharide from the fruiting bodies of Tremella aurantia. Biol Pharm Bull 18(12):1627–1629
Kolida S, Gibson GR (2007) Prebiotic capacity of inulin-type fructans. J Nutr 137(11 Suppl):2503S–2506S
Lattimer JM, Haub MD (2010) Effects of dietary fiber and its components on metabolic health. Nutrients 2:1266–1289
Lebovitz HE (2001) Insulin resistance: definition and consequences. Exp Clin Endocrinol Diabetes 109(Suppl 2):S135–S148
Leclère CJ, Champ M, Boillot J, Guille G, Lecannu G, Molis C, Bornet F, Krempf M, Delort-Laval J, Galmiche JP (1994) Role of viscous guar gums in lowering the glycemic response after a solid meal. Am J Clin Nutr 59(4):914–921
Lin D, Xiao M, Zhao J, Li Z, Xing B, Li X, Kong M, Li L, Zhang Q, Liu Y, Chen H, Qin W, Wu H, Chen S (2016) An overview of plant phenolic compounds and their importance in human nutrition and management of type 2 diabetes. Molecules 15(21:10):E1374
López-Romero P, Pichardo-Ontiveros E, Avila-Nava A, Vázquez-Manjarrez N, Tovar AR, Pedraza-Chaverri J, Torres N (2014) The effect of nopal (Opuntia ficus indica) on postprandial blood glucose, incretins, and antioxidant activity in Mexican patients with type 2 diabetes after consumption of two different composition breakfasts. J Acad Nutr Diet 114(11):1811–1818
Lu ZX, Walker KZ, Muir JG, Mascara T, O’Dea K (2000) Arabinoxylan fiber, a byproduct of wheat flour processing, reduces the postprandial glucose response in normoglycemic subjects. Am J Clin Nutr 71(5):1123–1128
Lu ZX, Walker KZ, Muir JG, O’Dea K (2004) Arabinoxylan fibre improves metabolic control in people with Type II diabetes. Eur J Clin Nutr 58:621–628
McIntosh M, Stone BA, Stanisich VA (2005) Curdlan and other bacterial (1→3)-β-D-glucans. Appl Microbiol Biotechnol 68(2):163–173
Neyrinck AM, Hiel S, Bouzin C, Garcia Campayo V, Cani PD, Bindels LB, Delzenne NM (2018) Wheat-derived arabinoxylan oligosaccharides with bifidogenic properties abolishes metabolic disorders induced by western diet in mice. Nutr Diabetes 8(15):1–5
Norgren M, Edlund H (2014) Lignin: recent advances and emerging applications. Edlund Curr Opin Colloid Interface Sci 19(5):409–416
Olano ME, Gibson GR, Rastell RA (2002) Comparison of the in vitro bifidogenic properties of pectins and pectic-oligosaccharides. J Appl Microbiol 93:505–511
Pahwa S, Sharma R, Singh B (2017) Role of glutathione S-transferase in coronary artery disease patients with and without Type 2 diabetes mellitus. J Clin Diagn Res 11(1):BC05–BBC8
Pearce KL, Noakes M, Keogh J, Clifton PM (2008) Effect of carbohydrate distribution on postprandial glucose peaks with the use of continuous glucose monitoring in type 2 diabetes. Am J Clin Nutr 87(3):638–644
Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM (1996) Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271(22):13018–13022
Picu A, Petcu L, Stefan S, Mitu M, Lixandru D, Ionescu-Tirgoviste C (2017) Markers of oxidative stress and antioxidant defense in Romanian patients with type 2 diabetes mellitus and obesity. Molecules 22(5):714
Pieme CA, Tatangmo JA, Simo G, Biapa Nya PC, Ama Moor VJ, Moukette Moukette B (2017) Relationship between hyperglycemia, antioxidant capacity and some enzymatic and non-enzymatic antioxidants in African patients with type 2 diabetes. BMC Res Notes 10(1):141
Pourghassem GB, Dehghan P, Aliasgharzadeh A, Asghari JAM (2013) Effects of high performance inulin supplementation on glycemic control and antioxidant status in women with type 2 diabetes. Diabetes Metab J 37(2):140–148
Reyna-Villasmil N, Bermúdez-Pirela V, Mengual-Moreno E, Arias N, Cano-Ponce C, Leal-Gonzalez E, Souki A, Inglett GE, Israili ZH, Hernández-Hernández R, Valasco M, Arraiz N (2007) Oat-derived β-glucan significantly improves HDLC and diminishes LDLC and non-HDL cholesterol in overweight individuals with mild hypercholesterolemia. Am J Ther 14(2):203–212
Ring SG, Selvendran RR (1980) Isolation and analysis of cell-wall material from beeswing wheat bran (Triticum aestivum). Phytochemistry 19:1723–1730
Roberfroid MB, Delzenne NM (1998) Dietary fructans. Annu Rev Nutr 18:117–143
Roden M (2016) Diabetes mellitus: definition, classification and diagnosis. Wien Klin Wochenschr 128(Suppl 2):37–40
Sadiq-Butt M, Tahir-Nadeem M, Khan MK, Shabir R, Butt MS (2008) Oat: unique among the cereals. Eur J Nutr 47(2):68–79
Sánchez-Tapia M, Aguilar-López M, Pérez-Cruz C, Pichardo-Ontiveros E, Wang M, Donovan SM, Tovar AR, Torres N (2017) Nopal (Opuntia ficus indica) protects from metabolic endotoxemia by modifying gut microbiota in obese rats fed high fat/sucrose diet. Sci Rep 7(1):4716
Scalbert A, Manach C, Morand C, Remesy C, Jimenez L (2005) Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr 45(4):287–306
Schonfeld J, Evans DF, Wingate DL (1997) Effect of viscous fiber (guar) on postprandial motor activity in human small bowel. Dig Dis Sci 42(8):1613–1617
Schwartz SE, Levine RA, Weinstock RS, Petokas S, Mills CA, Thomas FD (1988) Sustained pectin ingestion: effect on gastric emptying and glucose tolerance in non-insulin-dependent diabetic patients. Am J Clin Nutr 48(6):1413–1417
Seino Y, Fukushima M, Yabe D (2010) GIP and GLP-1, the two incretin hormones: similarities and differences. J Diabetes Investig 1(1–2):8–23
Sierra M, García JJ, Fernández N, Diez MJ, Calle AP (2002) Therapeutic effects of psyllium in type 2 diabetic patients. Eur J Clin Nutr 56(9):830–842
Slavin JL (1987) Dietary fiber: classification, chemical analyses, and food sources. J Am Diet Assoc 87(9):1164–1171
Slavin J (2013) Fiber and prebiotics: mechanisms and health benefits. Nutrients 5(4):1417–1435
Stintzing FC, Carle R (2005) Cactus stems (Opuntia spp.): a review on their chemistry, technology, and uses. Mol Nutr Food Res 49(2):175–194
Suganya N, Bhakkiyalakshmi E, Sarada DV, Ramkumar KM (2016) Reversibility of endothelial dysfunction in diabetes: role of polyphenols. Br J Nutr 116(2):223–246
Tan Z, Ruan X, Chen Y, Jiang J, Zhou Y, Qiu H, Qin G, Xu HG (2014) Heterogeneous associations of insoluble dietary fiber intake with suibsequent glycosylated Hb levels among Chinese adults with type-2 diabetes: a quantile regression approach. Br J Nutr 112(6):958–963
Tappy L, Gugolz E, Wursch P (1996) Effects of breakfast cereals containing various amounts of beta-glucan fibers on plasma glucose and insulin responses in NIDDM subjects. Diabetes Care 19(8):831–834
Topping DL, Clifton PM (2001) Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 81(3):1031–1064
Trowell H (1972) Ischemic heart disease and dietary fiber. Am J Clin Nutr 25(9):926–932
Turroni F, Marchesi JR, Foroni E, Gueimonde M, Shanahan F, Margolles A, Van Sinderen D, Ventura M (2009) Microbiomic analysis of the bifidobacterial population in the human distal gut. ISME J 3(6):745–751
Vilsboll T, Holst JJ (2004) Incretins, insulin secretion and type 2 diabetes mellitus. Diabetologia 47(3):357–366
Weickert MO, Pfeiffer AFH (2008) Metabolic effects of dietary fiber consumption and prevention of diabetes. J Nutr 138:439–442
Wu X, Ma C, Han L, Nawaz M, Gao F, Zhang X, Yu P, Zhao C, Li L, Zhou A, Wang J, Moore JE, Millar BC, Xu J (2010) Molecular characterisation of the faecal microbiota in patients with type II diabetes. Curr Microbiol 61(1):69–78
Wu GD, Chen J, Hoffmann C, Bittinger K, Chen YY, Keilbaugh SA, Bewtra M, Knights D, Walters WA, Knight R, Sinha R, Gilroy E, Gupta K, Baldassano R, Nessel L, Li H, Bushman FD, Lewis JD (2011) Linking long-term dietary patterns with gut microbial enterotypes. Science 334(6052):105–108
Wu Y, Ding Y, Tanaka Y, Zhang W (2014) Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. Int J Med Sci 11(11):1185–1200
Wu T, Rayner CK, Horowitz M (2016) Incretins. Handb Exp Pharmacol 233:137–171
Ximenes HMA, Hirata AE, Rocha MS, Curi R, Carpinelli AR (2007) Propionate inhibits glucose-induced insulin secretion in isolated rat pancreatic islets. Cell Biochem Funct 25(2):173–178
Yao B, Fang H, Xu W, Yan Y, Xu H, Liu Y, Mo M, Zhang H, Zhao Y (2014) Dietary fiber intake and risk of type 2 diabetes: a dose-response analysis of prospective studies. Eur J Epidemiol 29(2):79–88
Zeković DB, Kwiatkowski S, Vrvić MM, Jakovljević D, Moran CA (2005) Natural and modified (1→3)-β-D-glucans in health promotion and disease alleviation. Crit Rev Biotechnol 25(4):205–230
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Torres, N., Avila-Nava, A., Medina-Vera, I., Tovar, A.R. (2020). Dietary Fiber and Diabetes. In: Welti-Chanes, J., Serna-Saldívar, S., Campanella, O., Tejada-Ortigoza, V. (eds) Science and Technology of Fibers in Food Systems. Food Engineering Series. Springer, Cham. https://doi.org/10.1007/978-3-030-38654-2_9
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