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Obstructive Sleep Apnoea Syndrome and Arrhythmia: Results of 10 Years’ Experience

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The First Outstanding 50 Years of “Università Politecnica delle Marche”

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Abstract

Obstructive sleep apnoea syndrome (OSAS) is a sleep-related breathing (SBD) disorder characterized by intermittent episodes of partial or complete obstruction of the upper airway, leading to cessation of breathing while asleep. OSAS elicits a series of mechanical, hemodynamic, chemical, neural, and inflammatory responses with adverse consequences on the cardiovascular system. Among these, cardiac arrhythmias are a common problem in affected patients, including both brady and tachy-arrhythmic manifestations. The strong association between OSAS and arrhythmia has prompted in last decades significant research aimed to understanding the mechanism connecting the two conditions, to define prevalence, to prospect new therapies and to explain the synergic negative effects in terms of morbidity and mortality in affected patients. In our center experience since 2009, we have focused our interest on atrial fibrillation (AF) and sleep apnea with the aim to define prevalence of SBD in a real-life population affected by AF and to assess the role of SBD on atrial remodelling, AF recurrence and therapies. Moreover, we have studied the complex relation between sleep apnoea and heart failure in patients treated with cardiac resynchronization therapy. We will report a revision of literature about sleep apnoea, AF and furthermore the main findings of our research.

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Author information

Authors and Affiliations

  1. Clinica di Cardiologia e Aritmologia, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Via Conica 71, Ancona, Italy

    Laura Cipolletta, Alessia Urbinati, Maria Vittoria Matassini, Marchesani Francesca, Stefano Gasparini & Alessandro Capucci

Authors
  1. Laura Cipolletta
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  2. Alessia Urbinati
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  3. Maria Vittoria Matassini
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  4. Marchesani Francesca
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  5. Stefano Gasparini
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  6. Alessandro Capucci
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Corresponding author

Correspondence to Laura Cipolletta .

Editor information

Editors and Affiliations

  1. Department of Information Engineering (DII), Marche Polytechnic University, Ancona, Italy

    Sauro Longhi

  2. Department of Information Engineering (DII), Marche Polytechnic University, Ancona, Italy

    Andrea Monteriù

  3. Department of Information Engineering (DII), Marche Polytechnic University, Ancona, Italy

    Alessandro Freddi

  4. Department of Agricultural, Food and Environmental Sciences (D3A), Marche Polytechnic University, Ancona, Italy

    Lucia Aquilanti

  5. Ospedali Riuniti di Ancona, Ancona, Italy

    Maria Gabriella Ceravolo

  6. Department of Life and Environmental Sciences (DISVA), Marche Polytechnic University, Ancona, Italy

    Oliana Carnevali

  7. Department of Life and Environmental Sciences (DISVA), Marche Polytechnic University, Ancona, Italy

    Mario Giordano

  8. Ospedali Riuniti di Ancona, Ancona, Italy

    Gianluca Moroncini

Appendix

Appendix

See Figs. 1, 2, 3, and 4.

Fig. 1
figure 1

Correlation between atrial dimension and apnoea severity index (a mean arterial saturation; b arterial saturation >90% of time in bed

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Fig. 2
figure 2

Prevalence of SDB

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Fig. 3
figure 3

The AHI value during follow up in patients with or without SDB

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Fig. 4
figure 4

Example of cardiorespiratory monitoring at baseline and at 6 months in one patient

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Cipolletta, L., Urbinati, A., Matassini, M.V., Francesca, M., Gasparini, S., Capucci, A. (2020). Obstructive Sleep Apnoea Syndrome and Arrhythmia: Results of 10 Years’ Experience. In: Longhi, S., et al. The First Outstanding 50 Years of “Università Politecnica delle Marche”. Springer, Cham. https://doi.org/10.1007/978-3-030-33832-9_17

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  • DOI: https://doi.org/10.1007/978-3-030-33832-9_17

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