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Oral Tolerance and Prognosis in Food Allergy

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Pediatric Food Allergy

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Abstract

Many children with IgE-mediated food allergies will naturally develop tolerance as they age, whereas others have lifelong allergy. Prognosis and development of tolerance vary according to age of diagnosis, type of food allergen, skin prick and serum IgE test results, and several other factors. The oral food challenge is the only method that can determine whether someone with IgE-mediated food allergy is still allergic, but this is labor and time intensive and imposes risk of potential reaction. Monitoring children with food allergies over time and knowing when to consider an oral food challenge are important concepts for primary care clinicians and allergists to understand and apply to clinical practice. In addition, parents of food-allergic children need to be counseled regarding their child’s prognosis and potential to one day “outgrow” their allergies. This chapter addresses the issues surrounding the natural development of oral tolerance and prognosis of children with various food allergies.

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Authors and Affiliations

  1. Division of Allergy and Immunology, Nationwide Children’s Hospital and The Ohio State University College of Medicine, Columbus, OH, USA

    David R. Stukus

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  1. David R. Stukus
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Correspondence to David R. Stukus .

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  1. Center for Food Allergy and Asthma Research, Northwestern University Feinberg School of Medicine, Chicago, IL, USA

    Ruchi S. Gupta

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Stukus, D.R. (2020). Oral Tolerance and Prognosis in Food Allergy. In: Gupta, R. (eds) Pediatric Food Allergy . Springer, Cham. https://doi.org/10.1007/978-3-030-33292-1_16

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  • DOI: https://doi.org/10.1007/978-3-030-33292-1_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-33291-4

  • Online ISBN: 978-3-030-33292-1

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