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Substance-Use Disorders and Violence

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Violence and Mental Disorders

Part of the book series: Comprehensive Approach to Psychiatry ((CAP,volume 1))

Abstract

Substance use seems to be associated with increased prevalence levels of violent behaviour in both general population and psychiatric patients, with ‘dual-diagnosis’ clients showing high rates of risky and criminal behaviour and worse therapy compliance. Cases of drug-related aggressiveness mostly involve a number of molecules, e.g. ethanol, stimulants, cannabinoids, opiates, benzodiazepines, synthetic cannabinoids and synthetic cathinones. Consumers of the virtually few hundred, and up to a few thousand, substances currently available may present to the emergency departments without providing information about the substances(s) ingested and it is likely that standard drug tests will show negative results. An appropriate treatment/management plan to cope with the related acute behavioural and psychopathological disturbances is here discussed. Because of the complex behavioural and medical toxicity issues associated with drug intake, raising awareness and education of healthcare professionals on drugs’ health harms, interventions, harm reduction techniques and referral pathways are here deemed of particular relevance.

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References

  1. Coomber K, Mayshak R, Liknaitzky P, Curtis A, Walker A, Hyder S, Miller P. The role of illicit drug use in family and domestic violence in Australia. J Interpers Violence. 2019;11:886260519843288. https://doi.org/10.1177/0886260519843288. [Epub ahead of print].

    Article  Google Scholar 

  2. Schifano F. Recent changes in drug abuse scenarios: the new/novel psychoactive substances (NPS) phenomenon. Brain Sci. 2018;8(12):E221. https://doi.org/10.3390/brainsci8120221.

    Article  PubMed  Google Scholar 

  3. American Psychiatric Association (APA). Diagnostic and statistical manual of mental disorders. 5th ed. Arlington, VA: American Psychiatric Publishing; 2013.

    Book  Google Scholar 

  4. WHO. ICD-11 for Mortality and Morbidity Statistics (ICD-11-MMS). 2018. https://icd.who.int/browse11/l-m/en. Accessed 19 Apr 2019.

  5. Papaseit E, Farré M, Schifano F, Torrens M. Emerging drugs in Europe. Curr Opin Psychiatry. 2014;27(4):243–50. https://doi.org/10.1097/YCO.0000000000000071.

    Article  PubMed  Google Scholar 

  6. WHO. World report on violence and health. 2002. https://www.who.int/violence_injury_prevention/violence/world_report/en/. Accessed 25 Apr 2019.

  7. Nock MK, Borges G, Bromet EJ, Cha CB, Kessler RC, Lee S. Suicide and suicidal behavior. Epidemiol Rev. 2008;30(1):133–54.

    Article  PubMed  Google Scholar 

  8. WHO. Global health estimates 2016: estimates deaths by age, sex and cause. 2016. https://www.who.int/healthinfo/global_burden_disease/estimates/en/. Accessed 25 Apr 2019.

  9. WHO. National suicide prevention strategies progress, examples and indicators. 2018. https://www.who.int/mental_health/suicide-prevention/national_strategies_2019/en/. Accessed 25 Apr 2019.

  10. WHO. Preventing suicide: a global imperative. 2014. https://www.who.int/mental_health/suicide-prevention/world_report_2014/en/. Accessed 25 Apr 2019.

  11. Kwon M, Yang S, Park K, Kim DJ. Factors that affect substance users suicidal behavior: a view from the Addiction Severity Index in Korea. Ann General Psychiatry. 2013;12:35.

    Article  Google Scholar 

  12. Pereira-Morales AJ, Adan A, Camargo A, Forero DA. Substance use and suicide risk in a sample of young Colombian adults: an exploration of psychosocial factors. Am J Addict. 2017;26(4):388–94.

    Article  PubMed  Google Scholar 

  13. Dragisic T, Dickov A, Dickov V, Mijatovic V. Drug addiction as risk for suicide attempts. Mater Sociomed. 2015;27(3):188–91.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Maloney E, Degenhardt L, Darke S, Mattick RP, Nelson E. Suicidal behaviour and associated risk factors among opioid-dependent individuals: a case–control study. Addiction. 2007;102(12):1933–41.

    Article  PubMed  Google Scholar 

  15. Oyefeso A, Ghodse H, Clancy C, Corkery JM. Suicide among drug addicts in the UK. Br J Psychiatry. 1999;175:277–82.

    Article  CAS  PubMed  Google Scholar 

  16. Wilcox HC, Conner KR, Caine ED. Association of alcohol and drug use disorders and completed suicide: an empirical review of cohort studies. Drug Alcohol Depend. 2004;76(Suppl):S11–9.

    Article  PubMed  Google Scholar 

  17. McAllister M. Multiple meanings of self harm: a critical review. Int J Ment Health Nurs. 2003;12:177–85.

    Article  PubMed  Google Scholar 

  18. Skegg K. Self-harm. Lancet. 2010;376(9736):1471–83.

    Google Scholar 

  19. Whitlock J. Self-Injurious Behavior in Adolescents. PLoS Med. 2010;7(5):e1000240.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Hughes T, Szalacha LA, McNair R. Substance abuse and mental health disparities: comparisons across sexual identity groups in a national sample of young Australian women. Soc Sci Med. 2010;71:824–31.

    Article  PubMed  Google Scholar 

  21. Moller CI, Tait RJ, Byrne DG. Deliberate self-harm, substance use, and negative affect in nonclinical samples: a systematic review. Subst Abus. 2013;34(2):188–207.

    Article  PubMed  Google Scholar 

  22. Pattison EM, Kahan J. The deliberate self-harm syndrome. Am J Psychiatry. 1983;140:867–72.

    Article  CAS  PubMed  Google Scholar 

  23. Penn JV, Esposito CL, Schaeffer LE, Fritz GK, Spirito A. Suicide attempts and self- mutilative behavior in a juvenile correctional facility. J Am Acad Child Adolesc Psychiatry. 2003;42:762–9.

    Article  PubMed  Google Scholar 

  24. Riala K, Hakko H, Rasanen P. Nicotine dependence is associated with suicide attempts and self-mutilation among adolescent females. Compr Psychiatry. 2009;50:293–8.

    Article  PubMed  Google Scholar 

  25. Bross DC. World perspectives on child abuse: the fourth international resource book. Denver, CO: Kempe Children’s Center, University of Colorado School of Medicine; 2000.

    Google Scholar 

  26. Theodore AD, Runyan DK. A medical research agenda for child maltreatment: negotiating the next steps. Pediatrics. 1999;104:168–77.

    CAS  PubMed  Google Scholar 

  27. Hillis SD, Mercy J, Amobi A, Kress H. Global prevalence of past-year violence against children: a systematic review and minimum estimates. Pediatrics. 2016;137(3):e20154079.

    Article  PubMed  Google Scholar 

  28. Stoltenborgh M, van Ijzendoorn MH, Euser EM, Bakermans-Kranenburg MJ. A global perspective on child sexual abuse: meta-analysis of prevalence around the world. Child Maltreat. 2011;16(2):79–101.

    Article  PubMed  Google Scholar 

  29. Kepple NJ. The complex nature of parental substance use: examining past year and prior use behaviors as correlates of child maltreatment frequency. Subst Use Misuse. 2017;52(6):811–21.

    Article  PubMed  Google Scholar 

  30. Anda RF, Butchart A, Felitti VJ, Brown DW. Building a framework for global surveillance of the public health implications of adverse childhood experiences. Am J Prev Med. 2010;39(1):93–8.

    Article  PubMed  Google Scholar 

  31. Hillis SD, Anda RF, Felitti VJ, Nordenberg D, Marchbanks PA. Adverse childhood experiences and sexually transmitted diseases in men and women: a retrospective study. Pediatrics. 2000;106(1):e11.

    Article  CAS  PubMed  Google Scholar 

  32. Springer KW, Sheridan J, Kuo D, Carnes M. The long-term health outcomes of childhood abuse an overview and a call to action. J Gen Intern Med. 2003;18:864–70.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Elwyn L, Smith C. Child maltreatment and adult substance abuse: the role of memory. J Soc Work Pract Addict. 2013;13(3):269–94.

    Article  Google Scholar 

  34. Goldstein RB, Compton WM, Pulay AJ, Ruan WJ, Pickering RP, Stinson FS, et al. Antisocial behavioral syndromes and DSM-IV drug use disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Drug Alcohol Depend. 2007;90(2–3):145–58.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Ladd GT, Petry NM. Antisocial personality in treatment-seeking cocaine abusers: psychosocial functioning and HIV risk. J Subst Abus Treat. 2003;24(4):323–30.

    Article  Google Scholar 

  36. Luk JW, Worley MJ, Winiger E, Trim RS, Hopfer CJ, Hewitt JK, et al. Risky driving and sexual behaviors as developmental outcomes of co-occurring substance use and antisocial behavior. Drug Alcohol Depend. 2016;169:19–25.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Casadio P, Olivoni D, Ferrari B, Pintori C, Speranza E, Bosi M, et al. Personality disorders in addiction outpatients: prevalence and effects on psychosocial functioning. Subst Abuse. 2014;31(8):17–24.

    Google Scholar 

  38. Westermeyer J, Thuras P. Association of antisocial personality disorder and substance disorder morbidity in a clinical sample. Am J Drug Alcohol Abuse. 2005;31(1):93–110.

    Article  PubMed  Google Scholar 

  39. Brooner RK, Schmidt CW, Felch LJ, Bigelow GE. Antisocial behavior of intravenous drug abusers: implications for diagnosis of antisocial personality disorder. Am J Psychiatry. 1992;149(4):482–7.

    Article  CAS  PubMed  Google Scholar 

  40. Cottler LB, Price RK, Compton WM, Mager DE. Subtypes of adult antisocial behavior among drug abusers. J Nerv Ment Dis. 1995;183(3):154–61.

    Article  CAS  PubMed  Google Scholar 

  41. Žarkovic Palijan T, Mužinić L, Radeljak S. Psychiatric comorbidity in forensic psychiatry. Psychiatr Danub. 2009;21(3):429–36.

    Google Scholar 

  42. Tielbeek JJ, Vink JM, Polderman TJC, Popma A, Posthuma D, Verweij KJH. Genetic correlation of antisocial behaviour with alcohol, nicotine, and cannabis use. Drug Alcohol Depend. 2018;187:296–9.

    Article  PubMed  Google Scholar 

  43. Allroggen M, Rassenhofer M, Witt A, Plener PL, Brähler E, Fegert JM. The prevalence of sexual violence. Dtsch Arztebl Int. 2016;113(7):107–13.

    PubMed  PubMed Central  Google Scholar 

  44. Jahromi MK, Jamali S, Rahmanian Koshkaki A, Javadpour S. Prevalence and risk factors of domestic violence against women by their husbands in Iran. Glob J Health Sci. 2015;8(5):175–83.

    Article  PubMed Central  Google Scholar 

  45. U.S. Department of Justice—Full report of the prevalence, incidence, and consequences of violence against women. 2000. www.ncjrs.gov/pdffiles1/nij/183781.pdf. Accessed 5 Apr 2019.

  46. WHO. Multi-country study on women’s health and domestic violence against women. 2005. https://www.who.int/gender/violence/who_multicountry_study/summary_report/summary_report_English2.pdf. Accessed 5 Apr 2019.

  47. World Health Organisation [WHO] (2012). Understanding and addressing violence against women. Available from https://apps.who.int/iris/bitstream/handle/10665/77434/WHO_RHR_12.37_eng.pdf;jsessionid=8E7FDC40D041025A09BF8CB75379B936?sequence=1. Accessed 8 Oct, 2019.

  48. Coker AL, Smith PH, Bethea L, King MR, McKeown RE. Physical health consequences of physical and psychological intimate partner violence. Arch Fam Med. 2000;9(5):451–7.

    Article  CAS  PubMed  Google Scholar 

  49. Do VT, Ho HT, Nguyen TM, Do HK. Sexual violence and the risk of HIV transmission in sexual partners of male injecting drug users in Tien Du district, Bac Ninh province of Vietnam. Health Care Women Int. 2018;39(4):404–14.

    Article  PubMed  Google Scholar 

  50. Holmes MM, Resnick HS, Kilpatrick DG, Best CL. Rape-related pregnancy: estimates and descriptive characteristics from a national sample of women. Am J Obstet Gynecol. 1996;175(2):320–5.

    Article  CAS  PubMed  Google Scholar 

  51. Kaslow NJ, Thompson MP, Meadows LA, Jacobs D, Chance S, Gibb B, et al. Factors that mediate and moderate the link between partner abuse and suicidal behavior in African American women. J Consult Clin Psychol. 1998;66(3):533–40.

    Article  CAS  PubMed  Google Scholar 

  52. López-Castroman J, Melhem N, Birmaher B, Greenhill L, Kolko D, Stanley B, et al. Early childhood sexual abuse increases suicidal intent. World Psychiatry. 2013;12(2):149–54.

    Article  PubMed  PubMed Central  Google Scholar 

  53. Sutton TE, Gordon Simons L, Tyler KA. Hooking-up and sexual victimization on campus: examining moderators of risk. J Interpers Violence. 2019:886260519842178. https://doi.org/10.1177/0886260519842178

  54. Graham KR. The childhood victimization of sex offenders: an underestimated issue. Int J Offender Ther Comp Criminol. 1996;40(3):192–203.

    Article  Google Scholar 

  55. Jewkes R, Sikweyiya Y, Morrell R, Dunkle K. Gender inequitable masculinity and sexual entitlement in rape perpetration South Africa: findings of a cross-sectional study. PLoS One. 2011;6(12):e29590.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  56. Liakoni E, Gartwyl F, Ricklin M, Exadaktylos AK, Krähenbühl S. Psychoactive substances and violent offences: a retrospective analysis of presentations to an urban emergency department in Switzerland. PLoS One. 2018;13(3):e0195234.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  57. Grisso JA, Schwarz DF, Hirschinger N, Sammel M, Brensinger C, Santanna J, et al. Violent injuries among women in an urban area. N Engl J Med. 1999;341:1899–905.

    Article  CAS  PubMed  Google Scholar 

  58. Parrott DJ, Lisco CG. Effects of alcohol and sexual prejudice on aggression toward sexual minorities. Psychol Viol. 2015;5:256–65.

    Article  Google Scholar 

  59. Crane CA, Easton CJ. Physical health conditions and intimate partner violence perpetration among offenders with alcohol use diagnoses. J Interpers Violence. 2017 Jun;32(11):1678–91. https://doi.org/10.1177/0886260515590124.

    Article  PubMed  Google Scholar 

  60. Corkery JM, Loi B, Claridge H, Goodair C, Corazza O, Elliott S, et al. Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4 butanediol (1,4-BD, BDO): a literature review with a focus on UK fatalities related to non-medical use. Neurosci Biobehav Rev. 2015;53:52–78.

    Article  CAS  PubMed  Google Scholar 

  61. Schifano F, Corkery J, Oyefeso A, Tonia T, Ghodse AH. Trapped in the “K-hole”: overview of deaths associated with ketamine misuse in the UK (1993–2006). J Clin Psychopharmacol. 2008;28(1):114–6.

    Article  PubMed  Google Scholar 

  62. Giorgetti R, Tagliabracci A, Schifano F, Zaami S, Marinelli E, Busardò FP. When “chems” meet sex: a rising phenomenon called “chemsex”. Curr Neuropharmacol. 2017;15(5):762–70. https://doi.org/10.2174/1570159X15666161117151148.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Watts C, Zimmermann C. Violence against women: global scope and magnitude. Lancet. 2002;359(9313):1232–7.

    Article  PubMed  Google Scholar 

  64. Room R, Babor T, Rehm J. Alcohol and public health. Lancet. 2005;365(9458):519–30.

    Article  PubMed  Google Scholar 

  65. Amore M, Menchetti M, Tonti C, Scarlatti F, Lundgren E, Esposito W, et al. Predictors of violent behavior among acute psychiatric patients: clinical study. Psychiatry Clin Neurosci. 2008;62(3):247–55.

    Article  PubMed  Google Scholar 

  66. Schifano F, Orsolini L, Duccio Papanti G, Corkery JM. Novel psychoactive substances of interest for psychiatry. World Psychiatry. 2015;14(1):15–26. https://doi.org/10.1002/wps.20174.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Goldstein PJ. The drugs/violence nexus: a tripartite conceptual framework. J Drug Issues. 1985;15(4):493–506.

    Article  Google Scholar 

  68. Corkery JM, Schifano F, Oyefeso A, Ghodse AH, Tonia T, Naidoo V, et al. Review of literature and information on ‘khat-related’ mortality: a call for recognition of the issue and further research. Annali dell’Istituto Superiore di Sanitá. 2011;47(4):445–64.

    PubMed  Google Scholar 

  69. European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Drug-related homicide in Europe: a first review of the data and literature. 2018. http://www.emcdda.europa.eu/publications/emcdda-papers/drug-related-homicide-in-europe-review-data-literature_en. Accessed 5 Apr 2019.

  70. Heffernan R, Martin MJ, Romano AT. Homicides related to drug trafficking. Fed Probation. 1982;46(3):3–7.

    Google Scholar 

  71. Akers RL. Drugs, alcohol, and society: social structure, process, and policy. Belmont, CA: Wadsworth Publishing; 1992.

    Google Scholar 

  72. Hohl BC, Wiley S, Wiebe DJ, Culyba AJ, Drake R, Branas CC. Association of drug and alcohol use with adolescent firearm homicide at individual, family, and neighborhood levels. JAMA Intern Med. 2017;177(3):317–24.

    Article  PubMed  PubMed Central  Google Scholar 

  73. Office for National Statistics (ONS). Homicide in England and Wales: year ending March 2018. 2018. https://www.ons.gov.uk/peoplepopulationandcommunity/crimeandjustice/articles/homicideinenglandandwales/yearendingmarch2018#drug-and-alcohol-related-homicides. Accessed 5 Apr 2019.

  74. Corkery J. UK drug-related mortality—issues in definition and classification. Drugs Alcohol Today. 2008;8(2):17–25.

    Article  Google Scholar 

  75. Corkery J, Claridge H, Loi B, Goodair C, Schifano F. Drug-related deaths in the UK: Annual Report 2013. Drug-related deaths reported by coroners in England, Wales, Northern Ireland, Guernsey, Jersey and the Isle of Man; Police forces in Scotland; and the Northern Ireland Statistics and Research Agency—Annual Report January–December 2012. London: International Centre for Drug Policy, St Georges University of London. 2014. https://www.sgul.ac.uk/images/docs/idcp%20pdfs/National%20programme%20on%20substance%20abuse%20deaths/National_Programme_on_Substance_Abuse_Deaths-Annual_Report_2013_on_Drug-related_Deaths_in_the_UK_January-December_2012_PDF.pdf. Accessed 20 Apr 2019.

  76. HQIP. National Confidential Inquiry into Suicide and Homicide by People with Mental Illness. Annual Report 2017: England, Northern Ireland, Scotland and Wales. Healthcare Quality Improvement Partnership. University of Manchester. 2017. http://documents.manchester.ac.uk/display.aspx?DocID=37560. Accessed 20 Apr 2019.

  77. HQIP. National Confidential Inquiry into Suicide and Safety in Mental Health – Annual Report 2018: England, Northern Ireland, Scotland, Wales. Healthcare Quality Improvement Partnership. University of Manchester. 2018. http://documents.manchester.ac.uk/display.aspx?DocID=38469. Accessed 20 Apr 2019.

  78. Schifano F, Corkery J, Ghodse AH. Suspected and confirmed fatalities associated with mephedrone (4-methylmethcathinone, “meow meow”) in the United Kingdom. J Clin Psychopharmacol. 2012;32(5):710–4. https://doi.org/10.1097/JCP.0b013e318266c70c.

    Article  CAS  PubMed  Google Scholar 

  79. Oyefeso A, Schifano F, Ghodse H, Cobain K, Dryden R, Corkery J. Fatal injuries while under the influence of psychoactive drugs: a cross-sectional exploratory study in England. BMC Public Health. 2006;6:148.

    Article  PubMed  PubMed Central  Google Scholar 

  80. Chiappini S, Claridge H, Corkery JM, Goodair C, Loi B, Schifano F. Methoxetamine-related deaths in the UK: an overview. Hum Psychopharmacol Clin Exp. 2015;30(4):244–8.

    Article  Google Scholar 

  81. Corkery JM, Schifano F, Ghodse AH. Mephedrone-related fatalities in the United Kingdom: contextual, clinical and practical issues. In: Gallelli L, editor. Pharmacology. Rijeka: InTech—Open Access Publisher; 2012. p. 355–80.

    Google Scholar 

  82. European Drug Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Perspectives on drugs. Comorbidity of substance use and mental health disorders in Europe. 2016. http://www.emcdda.europa.eu/system/files/publications/2935/Comorbidity_POD2016.pdf. Accessed 4 Apr 2019.

  83. Substance Abuse and Mental Health Services Administration (SAMHSA). Behavioral health trends in the United States: results from the 2014 national survey on drug use and health. 2014. https://www.samhsa.gov/data/sites/default/files/NSDUH-FRR1-2014/NSDUH-FRR1-2014.htm#idtextanchor086. Accessed 4 Apr 2019.

  84. Gostin LO, Record KL. Dangerous people or dangerous weapons: access to firearms for persons with mental illness. JAMA. 2011;305(20):2108–9.

    Article  CAS  PubMed  Google Scholar 

  85. Latt N, Jurd S, Tennant C, Lewis J, Macken L, Joseph A, et al. Alcohol and substance use by patients with psychosis presenting to an emergency department: changing patterns. Australas Psychiatry. 2011;19:354.

    Article  PubMed  Google Scholar 

  86. Soyka M. Substance misuse, psychiatric disorder and violent and disturbed behaviour. Br J Psychiatry. 2000;176:345–50.

    Article  CAS  PubMed  Google Scholar 

  87. Swanson JW, Holzer CE III, Ganju VK, Jono RT. Violence and psychiatric disorder in the community: evidence from the Epidemiologic Catchment Area surveys. Hosp Community Psychiatry. 1990;41(7):761–70.

    CAS  PubMed  Google Scholar 

  88. Volavka J, Swanson J. Violent behavior in mental illness: the role of substance abuse. JAMA. 2010;304(5):563–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  89. Zhuo Y, Bradizza CM, Maisto SA. The influence of treatment attendance on subsequent aggression among severely mentally ill substance abusers. J Subst Abus Treat. 2014;47(5):353–61.

    Article  Google Scholar 

  90. Mueser KT, Yarnold PR, Levinson DF, Singh H, Bellack AS, Kee K, Morrison RL, Yadalam KG. Prevalence of substance abuse in schizophrenia: demographic and clinical correlates. Schizophr Bull. 1990;16(1):31–56.

    Article  CAS  PubMed  Google Scholar 

  91. Stompe T, Ritter K, Schanda H. Patterns of substance abuse in offenders with schizophrenia—illness-related or criminal life-style? Front. Psychiatry. 2018;9:233. https://doi.org/10.3389/fpsyt.2018.00233.

    Article  PubMed  PubMed Central  Google Scholar 

  92. Erkiran M, Ozunalan H, Cuneyt E, Aytaclar S, Kirisci L, Tarteret R. Substance abuse amplifies the risk for violence in schizophrenia spectrum disorder. Addict Behav. 2006;31:1797–805.

    Article  PubMed  Google Scholar 

  93. Swanson JW, Swartz MS, Van Dorn RA, Elbogen EB, Wagner HR, Rosenheck RA, et al. A national study of violent behaviour in persons with schizophrenia. Arch Gen Psychiatry. 2006;63:490–9.

    Article  PubMed  Google Scholar 

  94. Haddock G, Eisner E, Davies G, Coupe N, Barrowclough N. Psychotic symptoms, self-harm and violence in individuals with schizophrenia and substance misuse problems. Schizophr Res. 2013;151(1–3):215–20.

    Article  PubMed  Google Scholar 

  95. Link B, Stueve A. Psychotic symptoms and the violent/illegal behavior of mental patients compared to the community. In: Monahan J, Steadman H, editors. Violence and mental disorder: development in risk assessment. Chicago: University of Chicago Press; 1994. p. 137–58.

    Google Scholar 

  96. Maremmani AGI, Rugani F, Bacciardi S, Rovai L, Pacini M, Dell’Osso L, et al. Does dual diagnosis affect violence and moderate/superficial self-harm in heroin addiction at treatment entry? J Addict Med. 2014;8:116–22.

    Article  CAS  PubMed  Google Scholar 

  97. Alnıak I, Erkıran M, Mutlu E. Substance use is a risk factor for violent behaviour in male patients with bipolar disorder. J Affect Disord. 2016;193:89–93.

    Article  PubMed  Google Scholar 

  98. Fazel S, Lichtenstein P, Grann M, Goodwin GM, Langström N. Bipolar disorder and violent crime new evidence from population-based longitudinal studies and systematic review. Arch Gen Psychiatry. 2010;67(9):931–8.

    Article  PubMed  Google Scholar 

  99. Lewis CF. Substance use and violent behavior in women with antisocial personality disorder. Behav Sci Law. 2011;29:667–76.

    Article  PubMed  Google Scholar 

  100. Anderson PD, Bokor G. Forensic aspects of drug-induced violence. J Pharm Pract. 2012;25(1):41–9.

    Article  PubMed  Google Scholar 

  101. Ferner RE. Effects of drugs on behavior. Forensic pharmacology: medicines, mayhem, and malpractice. Oxford: Oxford University Press; 1996. p. 73–8.

    Google Scholar 

  102. Moore TJ, Glenmullen J, Furberg CD. Prescription drugs report with associated with reports of violence towards others. PLoS One. 2010;5(12):1–5.

    Article  CAS  Google Scholar 

  103. Steele JL, Peralta RL. Are polydrug users more physically and verbally aggressive? An assessment of aggression among mono- versus polydrug users in a university sample. J Interpers Violence. 2017:886260517715024. https://doi.org/10.1177/0886260517715024.

  104. Osgood DW, Johnston LD, O’Malley PM, Bachman JG. The generality of deviance in late adolescence and early adulthood. Am Sociol Rev. 1996;53(1):80–92.

    Google Scholar 

  105. Miyata J. Toward integrated understanding of salience in psychosis. Neurobiol Dis. 2019:S0969-9961(19)30061-0. https://doi.org/10.1016/j.nbd.2019.03.002.

    Article  PubMed  Google Scholar 

  106. Ntounas P, Katsouli A, Efstathiou V, Pappas D, Chatzimanolis P, Touloumis C, Papageorgiou C, Douzenis A. Comparative study of aggression—dangerousness on patients with paranoid schizophrenia: focus on demographic data, PANSS, drug use and aggressiveness. Int J Law Psychiatry. 2018;60:1–11. https://doi.org/10.1016/j.ijlp.2018.06.001.

    Article  PubMed  Google Scholar 

  107. Rouve N, Bagheri H, Telmon N, Pathak A, Franchitto N, Schmitt L, et al. Prescribed drugs and violence: a case/noncase study in the French pharmacovigilance database. Eur J Clin Pharmacol. 2011;67(11):1189–98.

    Article  PubMed  Google Scholar 

  108. Wolkers CPB, Serra M, Júnior AB, Urbinati EC. Acute fluoxetine treatment increases aggressiveness in juvenile matrinxã (Brycon amazonicus). Fish Physiol Biochem. 2017;43(3):755–9.

    Article  CAS  PubMed  Google Scholar 

  109. Gillet C, Polard E, Mauduit N, Allain H. Acting out and psychoactive substances: alcohol, drugs, illicit substances. Encephale. 2001;27(4):351–9.

    CAS  PubMed  Google Scholar 

  110. Miczek KA, DeBold JF, Hwa LS, Newman EL, de Almeida RMM. Alcohol and violence: neuropeptidergic modulation of monoamine systems. Ann N Y Acad Sci. 2015;1349(1):96–118.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  111. Kuypers K, Verkes RJ, van der Brink W, van Amsterdam JGC, Ramaekers JC. Intoxicated aggression: do alcohol and stimulants cause dose-related aggression? A review. Eur Neuropsychopharmacol. 2018:1–34. Pii: S0924-977X(18)30147-0. https://doi.org/10.1016/j.euroneuro.2018.06.001.

  112. Nikathil S, Olaussen A, Gocentas RA, Symons E, Mitra B. Workplace violence in the emergency department: a systematic review and meta-analysis. Emerg Med Australas. 2017;29(3):265–75.

    Article  PubMed  Google Scholar 

  113. Morgan MY. Acute alcohol toxicity and withdrawal in the emergency room and medical admissions unit. Clin Med (Lond). 2015;15(5):486–9.

    Article  Google Scholar 

  114. Miller NS, Gold MS, Mahler JC. Violent behaviors associated with cocaine use: possible pharmacological mechanisms. Int J Addict. 1991;26(10):1077–88.

    Article  CAS  PubMed  Google Scholar 

  115. Narvaez GCM, Jansen K, Pinheiro RT, Kapczinski F, Silva RA, Pechansky F, et al. Violent and sexual behaviors and lifetime use of crack cocaine: a population-based study in Brazil. Soc Psychiatry Psychiatr Epidemiol. 2014;49(8):1249–55.

    Article  PubMed  Google Scholar 

  116. Bunting PJ, Fulde GWO, Forster SL. Comparison of crystalline methamphetamine (“ICE”) users and other patients with toxicology-related problems presenting to a hospital emergency department. Med J Aust. 2007;187:564–6.

    Article  PubMed  Google Scholar 

  117. Vaughn MG, Salas-Wright CP, DeLisi M, Perron BE, Cordova D. Crime and violence among MDMA users in the United States. AIMS Public Health. 2015;2(1):64–73. https://doi.org/10.3934/publichealth.2015.1.64.

    Article  PubMed  PubMed Central  Google Scholar 

  118. Wood D, Sedefov R, Cunningham A, Dargan PI. Prevalence of use and acute toxicity associated with the use of NBOMe drugs. Clin Toxicol. 2015;53:85–92.

    Article  CAS  Google Scholar 

  119. Harro J. Neuropsychiatric adverse effects of amphetamine and methamphetamine. Int Rev Neurobiol. 2015;120:179–204.

    Article  CAS  PubMed  Google Scholar 

  120. Fulde GWO, Forster SL. The impact of amphetamine-type stimulants on emergency services. Curr Opin Psychiatry. 2015;28:275–9.

    Article  PubMed  Google Scholar 

  121. Ostrowsky MK. Does marijuana use lead to aggression and violent behavior? J Drug Educ. 2011;41(4):369–89.

    Article  PubMed  Google Scholar 

  122. Smith PH, Homish GG, Leonard KE, Collins RL. Marijuana withdrawal and aggression among a representative sample of U.S. marijuana users. Drug Alcohol Depend. 2013;132(0):63–8.

    Article  PubMed  PubMed Central  Google Scholar 

  123. Allsop DJ, Norberg MM, Copeland J, Fu S, Budney AJ. The Cannabis Withdrawal Scale development: patterns and predictors of cannabis withdrawal and distress. Drug Alcohol Depend. 2011;119:123–9.

    Article  PubMed  Google Scholar 

  124. Budney AJ, Hughes JR. The cannabis withdrawal syndrome. Curr Opin Psychiatry. 2006;19:233.

    Article  PubMed  Google Scholar 

  125. Kouri EM, Pope HG Jr, Lukas SE. Changes in aggressive behavior during withdrawal from long-term marijuana use. Psychopharmacology. 1999;143:302–8.

    Article  CAS  PubMed  Google Scholar 

  126. Barthelemy OJ, Richardson MA, Cabral HJ, Frank DA. Prenatal, perinatal, and adolescent exposure to marijuana: relationships with aggressive behaviour. Neurotoxicol Teratol. 2016;58:60–77.

    Article  CAS  PubMed  Google Scholar 

  127. Volkow ND, Baler RD, Compton WM, Weiss SRB. Adverse health effects of marijuana use. N Engl J Med. 2014;370:2219–27.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  128. Martinotti G, Cinosi E, Santacroce R, Papanti D, Pasquini A, Mancini V, et al. Substance-related psychopathology and aggressiveness in a nightlife holiday resort: results from a pilot study in a psychiatric inpatient unit in Ibiza. Hum Psychopharmacol Clin Exp. 2017;32:e2586.

    Article  CAS  Google Scholar 

  129. Kolla NJ, Mishra A. The endocannabinoid system, aggression, and the violence of synthetic cannabinoid use, borderline personality disorder, antisocial personality disorder, and other psychiatric disorders. Front Behav Neurosci. 2018;12:41.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  130. Schifano F. Substance misuse in the workplace. In: Ghodse AH, editor. Addiction at work: tackling drug use and misuse in the workplace. Aldershot: Gower Publishing Ltd; 2005. p. 53–67.

    Google Scholar 

  131. Hayhurst KP, Pierce M, Hickman M, Seddon T, Dunn G, Keane J, et al. Pathways through opiate use and offending: a systematic review. Int J Drug Policy. 2017;39:1–13.

    Article  PubMed  PubMed Central  Google Scholar 

  132. Schifano F, Chiappini S, Corkery J, Guirguis A. Assessing the 2004–2018 fentanyl misusing issues reported to an international range of adverse reporting systems. Front Pharmacol. 2019;10:46. https://doi.org/10.3389/fphar.2019.00046.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  133. El-Hadidy MA, Helaly AML. Medical and psychiatric effects of long-term dependence on high dose of tramadol. Subst Use Misuse. 2015;50(5):582–9.

    Article  PubMed  Google Scholar 

  134. Tae CH, Kang KJ, Min BH, Ahn JH, Kim S, Lee JH, Rhee PL, Kim JJ. Paradoxical reaction to midazolam in patients undergoing endoscopy under sedation: incidence, risk factors and the effect of flumazenil. Dig Liver Dis. 2014;46(8):710–5. https://doi.org/10.1016/j.dld.2014.04.007.

    Article  CAS  PubMed  Google Scholar 

  135. Reddy MSS, Achary U, Harbishettar V, Sivakumar PT, Varghese M. Paradoxical reaction to benzodiazepines in elderly—case series. Asian J Psychiatr. 2018;35:8–10. https://doi.org/10.1016/j.ajp.2018.04.037.

    Article  PubMed  Google Scholar 

  136. Saxon L, Borg S, Hiltunen AJ. Reduction of aggression during benzodiazepine withdrawal: effects of flumazenil. Pharmacol Biochem Behav. 2010;96(2):148–51.

    Article  CAS  PubMed  Google Scholar 

  137. Wallace PS, Taylor SP. Reduction of appeasement-related affect as a concomitant of diazepam-induced aggression: evidence for a link between aggression and the expression of self-conscious emotions. Aggress Behav. 2009;35:203–12.

    Article  PubMed  Google Scholar 

  138. Papanti D, Schifano F, Botteon G, Bertossi F, Mannix J, Vidoni D, Impagnatiello M, Pascolo-Fabrici E, Bonavigo T. “Spiceophrenia”: a systematic overview of “spice”-related psychopathological issues and a case report. Hum Psychopharmacol. 2013;28(4):379–89. https://doi.org/10.1002/hup.2312.

    Article  PubMed  Google Scholar 

  139. Courts J, Maskill V, Gray A, Glue P. Signs and symptoms associated with synthetic cannabinoid toxicity: systematic review. Australas Psychiatry. 2016;24(6):598–601.

    Article  PubMed  Google Scholar 

  140. Clayton HB, Lowry R, Ashley C, Wolkin A, Grant AM. Health risk behaviors with synthetic cannabinoids versus marijuana. Pediatrics. 2017;139(4):e20162675.

    Article  PubMed  Google Scholar 

  141. Armenian P, Darracq M, Gevorkyan J, Clark S, Kaye B, Brandehoff NP. Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: a case series and review of the literature. Neuropharmacology. 2018;134(Pt A):82–91.

    Article  CAS  PubMed  Google Scholar 

  142. Tournebize J, Gibaja V, Kahn JP. Acute effects of synthetic cannabinoids: update 2015. Subst Abus. 2017;38(3):344–66.

    Article  PubMed  Google Scholar 

  143. Roberts L, Ford L, Patel N, Vale JA, Bradberry SM. 11 analytically confirmed cases of mexedrone use among polydrug users. Clin Toxicol (Phila). 2017;55(3):181–6.

    Article  CAS  Google Scholar 

  144. Capriola M. Synthetic cathinone abuse. Clin Pharmacol. 2013;5:109–15.

    PubMed  PubMed Central  Google Scholar 

  145. James D, Adams RD, Spears R, Cooper G, Lupton DJ, Thompson JP, et al. Clinical characteristics of mephedrone toxicity reported to the UK National Poisons Information Service. Emerg Med J. 2011;28:686–9.

    Article  CAS  PubMed  Google Scholar 

  146. Schifano F, Albanese A, Fergus S, Stair JL, Deluca P, Corazza O, Davey Z, Corkery J, Siemann H, Scherbaum N, Farré M, Torrens M, Demetrovics Z, Ghodse AH, Psychonaut Web Mapping, ReDNet Research Groups. Mephedrone (4-methylmethcathinone; ‘meow meow’): chemical, pharmacological and clinical issues. Psychopharmacology. 2011;214(3):593–602. https://doi.org/10.1007/s00213-010-2070-x.

    Article  CAS  PubMed  Google Scholar 

  147. Diestelmann M, Zangl A, Herrle I, Koch E, Graw M, Paul LD. MDPV in forensic routine cases: psychotic and aggressive behavior in relation to plasma concentrations. Forensic Sci Int. 2018;283:72–84.

    Article  CAS  PubMed  Google Scholar 

  148. Gilligan J, Lee B. The psychopharmacologic treatment of violent youth. Ann N Y Acad Sci. 2004;1036(1):356–81.

    Article  CAS  PubMed  Google Scholar 

  149. Timmis S. Doctors should not be legally obliged to report youths at risk of knife crime. BMJ. 2019;365:l1973.

    Article  PubMed  Google Scholar 

  150. Miller GM, Tolan PH. The influence of parenting practices and neighborhood characteristics on the development of childhood aggression. J Community Psychol. 2019;47(1):135–46.

    Article  PubMed  Google Scholar 

  151. Oser CB, Harp K, Pullen E, Bunting AM, Stevens-Watkins D, Staton M. African-American women’s tobacco and marijuana use: the effects of social context and substance use perceptions. Subst Use Misuse. 2019;54(6):873–84. https://doi.org/10.1080/10826084.2018.1528464.

    Article  PubMed  PubMed Central  Google Scholar 

  152. Wang J, Xie H, Holland KM, Sumner SA, Balaji AB, David-Ferdon CF, et al. Self-directed violence after medical emergency department visits among youth. Am J Prev Med. 2019;56(2):205–14.

    Article  PubMed  Google Scholar 

  153. Fond G, Boyer L, Boucekine M, Girard V, Loubière S, Lenoir C, French Housing First Study Group, et al. Illness and drug modifiable factors associated with violent behavior in homeless people with severe mental illness: results from the French Housing First (FHF) program. Prog Neuropsychopharmacol Biol Psychiatry. 2019;90:92–6.

    Article  CAS  PubMed  Google Scholar 

  154. Kaunomäki J, Jokela M, Kontio R, Laiho T, Sailas E, Lindberg N. Interventions following a high violence risk assessment score: a naturalistic study on a Finnish psychiatric admission ward. BMC Health Serv Res. 2017;17(1):26.

    Article  PubMed  PubMed Central  Google Scholar 

  155. Ogloff JR, Daffern M. The dynamic appraisal of situational aggression: an instrument to assess risk for imminent aggression in psychiatric inpatients. Behav Sci Law. 2006;24(6):799–813.

    Article  PubMed  Google Scholar 

  156. Khadivi AN, Patel RC, Atkinson AR, Levine JM. Association between seclusion and restraint and patient-related violence. Psychiatr Serv. 2004;55(11):1311–2.

    Article  PubMed  Google Scholar 

  157. Schifano F, Orsolini L, Papanti GD, Corkery JM. NPS: medical consequences associated with their intake. Curr Top Behav Neurosci. 2017;32:351–80. https://doi.org/10.1007/7854_2016_15.

    Article  CAS  PubMed  Google Scholar 

  158. Schifano F, Chiappini S, Corkery JM, Guirguis A. Abuse of prescription drugs in the context of novel psychoactive substances (NPS): a systematic review. Brain Sci. 2018 Apr 22;8(4):pii: E73. https://doi.org/10.3390/brainsci8040073.

    Article  CAS  Google Scholar 

  159. Guirguis A, Corkery J, Stair J, Kirton S, Zloh M, Schifano F. Intended and unintended use of cathinone mixtures. Hum Psychopharmacol Clin Exp. 2017;32(3). https://doi.org/10.1002/hup.2598.

    Article  CAS  Google Scholar 

  160. Mauri MC, Rovera C, Paletta S, De Gaspari IF, Maffini M, Altamura AC. Aggression and psychopharmacological treatments in major psychosis and personality disorders during hospitalisation. Prog Neuro-Psychopharmacol Biol Psychiatry. 2011;35(7):1631–5.

    Article  CAS  Google Scholar 

  161. Swanson JW, Swartz MS, Van Dorn RA, Volavka J, Monahan J, Stroup TS, et al. Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia. Br J Psychiatry. 2008;193(1):37–43.

    Article  PubMed  PubMed Central  Google Scholar 

  162. Patchan K, Vyas G, Hackman AL, Mackowick M, Richardson CM, Love RC, et al. Clozapine in reducing aggression and violence in forensic populations. Psychiatry Q. 2018;89(1):157–68.

    Article  Google Scholar 

  163. Volavka J. Violence in schizophrenia and bipolar disorder. Psychiatr Danub. 2013;25(1):0–33.

    CAS  Google Scholar 

  164. Valeriani G, Corazza O, Bersani FS, Melcore C, Metastasio A, Bersani G, Schifano F. Olanzapine as the ideal ‘trip terminator’? Analysis of online reports relating to antipsychotics’ use and misuse following the occurrence of novel psychoactive substance-related psychotic symptoms. Human Psychopharmacol Clin Exp. 2015;30:249–54.

    Article  Google Scholar 

  165. Kasinathan J, Sharp G, Barker A. Evaluation of olanzapine pamoate depot in seriously violent males with schizophrenia in the community. Ther Adv Psychopharmacol. 2016;6(5):301–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  166. Volavka J, Citrome L. Pathways to aggression in schizophrenia affect results of treatment. Schizophr Bull. 2011;37(5):921–9.

    Article  PubMed  PubMed Central  Google Scholar 

  167. Jones RM, Arlidge J, Gillham R, Reagu S, van den Bree M, Taylor PJ. Efficacy of mood stabilisers in the treatment of impulsive or repetitive aggression: systematic review and meta-analysis. Br J Psychiatry. 2011;198(2):93–8.

    Article  PubMed  Google Scholar 

  168. Lindenmayer JP, Kotsaftis A. Use of sodium valproate in violent and aggressive behaviors: a critical review. J Clin Psychiatry. 2000;61(2):123–8.

    Article  CAS  PubMed  Google Scholar 

  169. Maremmani I, Pacini M, Lamanna F, Pani PP, Perugi G, Deltito J, et al. Mood stabilizers in the treatment of substance use disorders. CNS Spectr. 2010;15(02):95–109.

    Article  PubMed  Google Scholar 

  170. Martinotti G, Di Nicola M, Romanelli R, Andreoli S, Pozzi G, Moroni N, et al. High and low dosage oxcarbazepine versus naltrexone for the prevention of relapse in alcohol-dependent patients. Hum Psychopharmacol. 2007;22:149–56.

    Article  CAS  PubMed  Google Scholar 

  171. Molero Y, Zetterqvist J, Binswanger IA, Hellner C, Larsson H, Fazel S. Medications for alcohol and opioid use disorders and risk of suicidal behavior, accidental overdoses, and crime. Am J Psychiatry. 2018;175(10):970–8.

    Article  PubMed  PubMed Central  Google Scholar 

  172. Chang Z, Lichtenstein P, Långström N, Larsson H, Fazel S. Association between prescription of major psychotropic medications and violent reoffending after prison release. JAMA. 2016;316:1798–807.

    Article  PubMed  PubMed Central  Google Scholar 

  173. Hedrich D, Alves P, Farrell M, Stöver H, Møller L, Mayet S. The effectiveness of opioid maintenance treatment in prison settings: a systematic review. Addiction. 2012;107:501–17.

    Article  PubMed  Google Scholar 

  174. Miller WR, Rollnick S. Motivational interviewing: preparing people to change addictive behavior. New York: Guilford Press; 1991.

    Google Scholar 

  175. López-Castro T, Smith KZ, Nicholson RA, Armas A, Hien DA. Does a history of violent offending impact treatment response for comorbid PTSD and substance use disorders? A secondary analysis of a randomized controlled trial. J Subst Abus Treat. 2019;97:47–58.

    Article  Google Scholar 

  176. McMurran M. Motivational interviewing with offenders: a systematic review. Leg Criminol Psychol. 2009;14(1):83–100.

    Article  Google Scholar 

  177. Cunningham RM, Chermack ST, Zimmerman MA, Shope JT, Bingham CR, Blow FC, et al. Brief motivational interviewing intervention for peer violence and alcohol use in teens: one-year follow-up. Pediatrics. 2012;129(6):1083.

    Article  PubMed  PubMed Central  Google Scholar 

  178. Zatzick D, Russo J, Lord SP, Varley C, Wang J, Berliner L, et al. Collaborative care intervention targeting violence risk behaviors, substance use, and posttraumatic stress and depressive symptoms in injured adolescents: a randomized clinical trial. JAMA Pediatr. 2014;168(6):532–9.

    Article  PubMed  Google Scholar 

  179. Steinauer R, Huber CG, Petitjean S, Wiesbeck GA, Dürsteler KM, Lang UE, et al. Effect of door-locking policy on inpatient treatment of substance use and dual disorders. Eur Addict Res. 2017;23(2):87–96.

    Article  PubMed  Google Scholar 

  180. Hedlund J, Forsman J, Sturup J, Masterman T. Psychotropic medications in Swedish homicide victims and offenders: a forensic-toxicological case-control study of adherence and recreational use. J Clin Psychiatry. 2017;78(7):e797–802.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Psychopharmacology, Drug Misuse, and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK

    Fabrizio Schifano, Caroline Zangani, Stefania Chiappini & John M. Corkery

  2. Swansea University Medical School, Institute of Life Sciences 2, Swansea University, Swansea, Wales, UK

    Amira Guirguis

  3. Camden and Islington NHS Mental Health Foundation Trust, London, UK

    Stefania Bonaccorso

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  1. Fabrizio Schifano
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  2. Caroline Zangani
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  3. Stefania Chiappini
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  4. Amira Guirguis
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  5. Stefania Bonaccorso
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  6. John M. Corkery
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  1. Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy

    Bernardo Carpiniello

  2. Department of Clinical and Experimental Science, University of Brescia, Brescia, Italy

    Antonio Vita

  3. Department of Neuroscience, Luigi Sacco Hospital, Milano, Italy

    Claudio Mencacci

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Schifano, F., Zangani, C., Chiappini, S., Guirguis, A., Bonaccorso, S., Corkery, J.M. (2020). Substance-Use Disorders and Violence. In: Carpiniello, B., Vita, A., Mencacci, C. (eds) Violence and Mental Disorders. Comprehensive Approach to Psychiatry, vol 1. Springer, Cham. https://doi.org/10.1007/978-3-030-33188-7_6

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