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Brief Cognitive Tests in the Case of Dementia and Alzheimer’s Disease Early Diagnosis

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GeNeDis 2018

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1195))

Abstract

Nowadays, Alzheimer’s disease (AD) diagnosis is considered to be a crucial and extremely complex process. Nevertheless, psychometric tools, like Mini-Mental State Evaluation (MMSE), are used to address cognitive function assessment and clinical evaluation processes. However, MMSE’s sensitivity in the diagnosis of mild cognitive impairment is debatable in terms of education, age, or nationality. Typical psychometric tools with the use of “paper and pencil” methods combined with physiology measurements are proposed in order to enhance validity and effectiveness in the case of Alzheimer’s disease cognitive deficits. The objective of this review study is to highlight the effectiveness of brief cognitive tests (BCT) in the case of dementia and Alzheimer’s disease screening. Authors’ future work will focus on the application of BCT in MCI diagnosis and evaluation.

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References

  • Alsaffar H, Wilson L, Kamdar DP, Sultanov F, Enepekides D, Higgins K (2016) Informed consent: do information pamphlets improve post-operative risk-recall in patients undergoing total thyroidectomy: prospective randomized control study. J Otolaryngol Head Neck Surg 45:14

    Article  PubMed  PubMed Central  Google Scholar 

  • American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders, vol 3. American Psychiatric Association, Washington, DC

    Google Scholar 

  • Aprahamian I, Diniz BS, Izbicki R, Radanovic M, Nunes PV, Forlenza O (2011) Optimizing the CAMCOG test in the screening for mild cognitive impairment and incipient dementia: saving time with relevant domains. Int J Geriatr Psychiatry 26(4):403–408

    Article  PubMed  Google Scholar 

  • Aretouli E, Tsilidis KK, Brandt J. (2013). Four-year outcome of mild cognitive impairment: The contribution of executive dysfunction. Neuropsychology, 27:95–106. [PubMed: 23106114]

    Google Scholar 

  • Bamford C, Lamont S, Eccles M, Robinson L, May C, Bond J (2004) Disclosing a diagnosis of dementia: a systematic review. Int J Geriatr Psychiatry 19(2):151–169

    Article  PubMed  Google Scholar 

  • Barral AG, Cacho J, Navarro E (2016) Practical application of brief cognitive tests. Neurologia 31(3):183–194

    Article  Google Scholar 

  • Beber B, Kochhann R, Matias B (2016) The clock drawing test performance differences between the free-drawn and incomplete-copy versions in patients with MCI and dementia. Dementia Neuropsychologia 10(3):227–231

    Article  PubMed  PubMed Central  Google Scholar 

  • Borson SOO, Scanlan J, Brush M, Vitaliano P, Dokmak A (1999) Τhe mini-cog a cognitive vital signs measure for dementia screening in multilingual elderly. Int J Geriatric Psychiatric 15:1021–1027

    Article  Google Scholar 

  • Borson S, Scanlan JM, Chen P et al (2003) The mini-cog as a screen for dementia: validation in a population-based sample. J Am Geriatr Soc 51(1):1451–1454

    Article  PubMed  Google Scholar 

  • Burns A, Jacoby R, Levy R (1990) Psychiatric phenomena in Alzheimer’s disease. IV: Disorders of behaviour. Br J Psychiatry 157:86–94

    Article  CAS  PubMed  Google Scholar 

  • Callahan CM (2002) Six-item screener to identify cognitive impairment among potential subjects for clinical research. Med Care 40(9):771–781

    Article  PubMed  Google Scholar 

  • Cordell CB, Borson S, Boustani M, Chodosh J, Reuben D, Verghese J, Fried LB (2013) Alzheimer’s Association recommendations for operationalizing the detection of cognitive impairment during the Medicare Annual Wellness Visit in a primary care setting. Alzheimer’s and Dementia, 9(2):141–150

    Google Scholar 

  • Davous P, Lamour Y, Debrand E, Rondot P (1987) A comparative evaluation of the short orientation memory concentration test of cognitive impairment. J Neurol Neurosurg Psychiatry 7(50):1312–1317

    Article  Google Scholar 

  • Dubois B, Touchon J, Portet F, Ousset PJ, Vellas B, Michel B (1983) The “5 words”: a simple and sensitive test for the diagnosis of Alzheimer’s disease. La Presse Médicale J 31:1696–1699

    Google Scholar 

  • Endlebury STP, Laus SPK, Ather MM, Rito MDEB, Harton RM (2015) Routine cognitive screening in older patients admitted to acute medicine: abbreviated mental test score (AMTS) and subjective memory complaint versus Montreal cognitive assessment and IQCODE. Age Ageing 44:1000–1005

    Article  Google Scholar 

  • Fage B, Chan C, Gill S (2015) Mini-cog for the diagnosis of Alzheimer ‘s disease dementia and other dementias within a community setting. Cochrane Libr 2:1–35

    Google Scholar 

  • Fichman-charchat H, Miranda CV, Fernandes CS, Mograbi D, Oliveira RM, Novaes R, Aguiar D (2015) Brief Cognitive Screening Battery (BCSB) is a very useful tool for diagnosis of probable mild Alzheimer’s disease in a geriatric clinic. Arq Neuropsiquiatr 74(2):149–154

    Article  PubMed  Google Scholar 

  • Fleming KC, Adams AC, Petersen RC (1995) Dementia: diagnosis and evaluation. Mayo Clin Proc 70(11):1093–1107

    Article  CAS  PubMed  Google Scholar 

  • Folstein MF, Folstein SE, McHugh PR (1975) “Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189–198

    Article  CAS  PubMed  Google Scholar 

  • Galvin JE, Sadowsky CH (2012) Practical Guidelines for the Recognition and Diagnosis of Dementia. Guidelines for Diagnosis of Dementia, 25(3):367–382

    Google Scholar 

  • Grossman M, Libon DJ, Forman MS, Massimo L, Wood E (2007) Distinct Antemortem profiles in patients with pathologically defined frontotemporal dementia. Arch Neurol 64(11):1601–1609

    Article  PubMed  Google Scholar 

  • Holsinger T, Deveau J, Boustani M, Williams JW (2013) Does this patient have dementia? J Am Med Assoc 297(21):2391–2404

    Article  Google Scholar 

  • Hsieh S, Mcgrory S, Leslie F, Dawson K et al (2015) The mini-Addenbrooke’s cognitive examination: a new assessment tool for dementia. Dement Geriatr Cogn Disord 2031(39):1–11

    Article  Google Scholar 

  • Ivnik RJ, Tangalos EG, Boeve BF, Petersen RC (2003) Comparison of the short test of mental status and the mini-mental state examination in mild cognitive impairment. Arch Neurol 60:1777–1781

    Article  PubMed  Google Scholar 

  • Johnson DK, Storandt M, Morris JC, Galvin JE (2009) Longitudinal study of the transition from healthy aging to Alzheimer disease. Arch Neurol 66(10):1254–1259

    Article  PubMed  PubMed Central  Google Scholar 

  • Kim M-J, Han C-W, Min K-Y, Cho C-Y, Lee C-W, Ogawa Y, Kohzuki M (2016) Physical exercise with multicomponent cognitive intervention for older adults with Alzheimer’s disease: a 6-month randomized controlled trial. Dementia Geriatric Cognit Disord Extr 6(2):222–232

    Article  Google Scholar 

  • Lin JS, Connor EO, Rossom RC (2013) Screening for cognitive impairment in older adults: an evidence update for the U.S. preventive services task force. Agency Healthcare Res Qual 107:14-05198-EF-1

    Google Scholar 

  • Malhotra C, Chan A, Matchar D, Seow D, Chuo A (2013) Diagnostic performance of short portable mental status questionnaire for screening dementia among patients attending cognitive assessment clinics in Singapore. Ann Acad Med Singapore 42(7):315–319

    PubMed  Google Scholar 

  • Mathuranath PS, Nestor PJ, Berrios GE, Rakowicz W, Hodges JR (2000) A brief cognitive test battery to differentiate Alzheimer’s disease and frontotemporal dementia. Neurology 55:1613–1620

    Article  CAS  PubMed  Google Scholar 

  • Mendiondo MS, Ashford JW, Kryscio RJ, Schmitt FA (2003) Designing a brief Alzheimer screen (BAS). J Alzheimers Dis 5:391–398

    Article  PubMed  Google Scholar 

  • Mitchell AJ, Psych MRC, Malladi S, Psych MRC (2010a) Screening and case finding tools for the detection of dementia part I: evidence-based meta-analysis of multidomain tests. Am J Geriatr Psychiatr 18(9):759–782

    Article  Google Scholar 

  • Mitchell AJ, Psych MRC, Malladi S, Psych MRC (2010b) Screening and case-finding tools for the detection of dementia part II: evidence-based meta-analysis of single-domain tests. Am J Geriatr Psychiatr 18(9):783–800

    Article  Google Scholar 

  • Naqvi RM, Sehrish H, Tomlinson G, Alibhai S (2015) Cognitive assessments in multicultural populations using the Rowland universal dementia assessment scale: a systematic review and meta-analysis. Can Med Assoc J 187(5):169–176

    Article  Google Scholar 

  • Olazarán J, Hoyos-Alonso MC, del Serc T et al (2016) Practical application of brief cognitive tests. Neurologia 31(3):183–194

    Article  PubMed  Google Scholar 

  • Panegyres PK, Berry R, Burchell J (2016) Early dementia screening. Diagnostics 6(1):6

    Article  PubMed Central  CAS  Google Scholar 

  • de Paula JJ, Bertola L, Ávila RT, Moreira L, Coutinho G, de Moraes EN, Malloy-Diniz LF (2013) Clinical applicability and cutoff values for an unstructured neuropsychological assessment protocol for older adults with low formal education. PLoS One 8(9):e73167

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Rajan KB, Wilson RS, Weuve J, Barnes LL, Evans DA (2015) Cognitive impairment 18 years before clinical diagnosis of Alzheimer disease dementia. Am Acad Neurol 85:898–904

    CAS  Google Scholar 

  • Reyes MA, Perez-Lloret S, Roldan Gerschcovich E, Martin ME, Leiguarda R, Merello M (2009) Addenbrooke’s cognitive examination validation in Parkinson’s disease. Eur J Neurol 16:142–147

    Article  CAS  PubMed  Google Scholar 

  • Ricci M, Pigliautile M, Ambrosio VD, Ercolani S et al (2016) The clock drawing test as a screening tool in mild cognitive impairment and very mild dementia: a new brief method of scoring and normative data in the elderly. In: Neurological Sci, vol 37, p 867

    Google Scholar 

  • Sager M a, Hermann BP, La Rue A, Woodard JL (2006) Screening for dementia in community-based memory clinics. WMJ 105(7):25–29

    PubMed  Google Scholar 

  • Salthouse TA (2012) What cognitive abilities are involved in trail-making performance? Intelligence 39(4):222–232

    Article  Google Scholar 

  • Schneider ALC, Gottesman F (2013) Cognition and incident dementia hospitalization: results from the atherosclerosis risk in communities study. Neuroepidemiology 40:117–124

    Article  PubMed  Google Scholar 

  • Shulman KI, Herrmann N, Brodaty H, Chiu H, Lawlor B, Ritchie K, James M (2006) IPA survey of brief cognitive screening. Int Psychogeriatr 18(2):281–294

    Article  PubMed  Google Scholar 

  • Solomon PR, Murphy CA (2005) Clinical challenges Alzheimer’ s disease in primary care practice. Geriatrics 60(11):26–31

    PubMed  Google Scholar 

  • Szcześniak D, Rymaszewska J (2015) The usefulness of the SLUMS test for diagnosis of mild cognitive impairment and dementia. Psychiatr Pol 2674(18):1–15

    Google Scholar 

  • Tombaugh T (2004) Trail making test a and B: normative data stratified by age and education. Arch Clin Neuropsychol 19:203–214

    Article  PubMed  Google Scholar 

  • Tombaugh TN, McIntyre NJ (1992) The mini-mental state examination: a comprehensive review. J Am Geriatr Soc 40:922–935

    Article  CAS  PubMed  Google Scholar 

  • Twamley EW, Legendre Ropacki SA, Bondi MW (2006) Neuropsychological and neuroimaging changes in preclinical Alzheimer’s disease. J Int Neuropsychol Soc 12(5):707–735

    Article  PubMed  PubMed Central  Google Scholar 

  • Velayudhan L, Ryu S, Raczek M, Philpot M, Lindesay J, Critchfield M, Livingston G (2014a) Review of brief cognitive tests for patients with suspected dementia. Int Psychogeriatr 26(8):1247–1262

    Article  PubMed  PubMed Central  Google Scholar 

  • Velayudhan L, Ryu S, Raczek M, Philpot M, Lindesay J, Critchfield M, Livingston G (2014b) Review of brief cognitive tests for patients with suspected. Int Psychogeriatr 26(8):1247–1262

    Article  PubMed  PubMed Central  Google Scholar 

  • Villars H, Oustric S, Andrieu S, Baeyens JP, Bernabei R, Brodaty H, Vellas B (2010) The primary care physician and Alzheimer’s disease: an international position paper. J Nutrition Health Aging 14(2):110–120

    Article  CAS  Google Scholar 

  • Vogel SJ, Banks SJ, Cummings JL, Miller JB (2015) Concordance of the Montreal cognitive assessment with standard neuropsychological measures. Alzheimer’s Dement 1(3):289–294

    Google Scholar 

  • Vyhnálek M, Rubínová E, Marková H, Nikolai T, Laczó J, Andel R, Hort J (2016) Clock drawing test in screening for Alzheimer’ s dementia and mild cognitive impairment in clinical practice. Int J Geriatr Psychiatry 32(9):933–939

    Article  PubMed  Google Scholar 

  • Wang LY, Leverenz JB, Vavrek DA (2009) Cognitive impairment in older adults without dementia: clinical and pathological outcomes in a community-based sample. J Geriatr Psychiatry Neurol 22(4):256–265

    Article  PubMed  PubMed Central  Google Scholar 

  • Weintraub S, Wicklund AH, Salmon DP (2012) The neuropsychological profile of Alzheimer disease. Cold Spring Harb Perspect Med 2:1–18

    Article  Google Scholar 

  • Wilcock J, Carroll RO (2009) Concordance with clinical practice guidelines for dementia in general practice. Aging Ment Health 13(2):155

    Article  PubMed  Google Scholar 

  • Yoo DH, Lee JS (2016) Clinical usefulness of the clock drawing test applying research analysis in predicting cognitive impairment. J Phys Ther Sci 28:2140–2143

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Informatics, Ionian University, Corfu, Greece

    Maria Sagiadinou & Antonia Plerou

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  1. Maria Sagiadinou
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  2. Antonia Plerou
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Editors and Affiliations

  1. Department of Informatics, Ionian University, Corfu, Greece

    Panayiotis Vlamos

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Sagiadinou, M., Plerou, A. (2020). Brief Cognitive Tests in the Case of Dementia and Alzheimer’s Disease Early Diagnosis. In: Vlamos, P. (eds) GeNeDis 2018. Advances in Experimental Medicine and Biology, vol 1195. Springer, Cham. https://doi.org/10.1007/978-3-030-32633-3_17

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