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Pattern Strabismus: Where Does the Role of the Brain End and the Role of Muscles Begin?

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Advances in Translational Neuroscience of Eye Movement Disorders

Part of the book series: Contemporary Clinical Neuroscience ((CCNE))

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Abstract

Pattern strabismus is a vertically incomitant horizontal strabismus comprising 50% of its infantile forms. High-resolution orbit imaging and contemporary physiology literature suggested the role of oblique muscle dysfunction as its pathophysiology. The role of the central nervous system was also outlined. Here, we will discuss contemporary theories with specific focus on pathophysiological concepts including oblique muscle dysfunction, loss of fusion with altered recti muscle pull, displacements and instability in connective tissue pulleys of the recti muscles, vestibular hypofunction, and abnormal neural connections.

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Author information

Authors and Affiliations

  1. Department of Neurology, Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, USA

    Nataliya Pyatka

  2. Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Fatema Ghasia

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  1. Nataliya Pyatka
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  2. Fatema Ghasia
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Correspondence to Nataliya Pyatka .

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Editors and Affiliations

  1. Neurological Institute, University Hospitals Neurology Service, Louis Stokes Cleveland, VA Medical Center, Department of Neurology, Case Western Reserve University, Cleveland, OH, USA

    Aasef Shaikh

  2. Pediatric Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Fatema Ghasia

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Pyatka, N., Ghasia, F. (2019). Pattern Strabismus: Where Does the Role of the Brain End and the Role of Muscles Begin?. In: Shaikh, A., Ghasia, F. (eds) Advances in Translational Neuroscience of Eye Movement Disorders. Contemporary Clinical Neuroscience. Springer, Cham. https://doi.org/10.1007/978-3-030-31407-1_14

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