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Ginseng Genome Structure and Evolution

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The Ginseng Genome

Part of the book series: Compendium of Plant Genomes ((CPG))

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Abstract

Ginseng (Panax ginseng) genome has been difficult to unlock its genomics due to its size, high repeat content, and polyploidy nature. Although chromosome-scale genome assembly for ginseng holds numerous challenges, a draft gene space assembly can open many avenues for ginseng crop improvements. This chapter provides an overview of the current ginseng genomic status, evolution, gene annotation of novel genes associated with repeat evolution, and environmental adaptations.

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References

  • Cock JM, Sterck L, Rouzé P, Scornet D, Allen AE, Amoutzias G, Anthouard V, Artiguenave F, Aury JM, Badger JH, Beszteri B, Billiau K, Bonnet E, Bothwell JH, Bowler C, Boyen C, Brownlee C, Carrano CJ, Charrier B, Cho GY, Coelho SM, Collén J, Corre E, Da Silva C, Delage L, Delaroque N, Dittami SM, Doulbeau S, Elias M, Farnham G, Gachon CM, Gschloessl B, Heesch S, Jabbari K, Jubin C, Kawai H, Kimura K, Kloareg B, Küpper FC, Lang D, Le Bail A, Leblanc C, Lerouge P, Lohr M, Lopez PJ, Martens C, Maumus F, Michel G, Miranda-Saavedra D, Morales J, Moreau H, Motomura T, Nagasato C, Napoli CA, Nelson DR, Nyvall-Collén P, Peters AF, Pommier C, Potin P, Poulain J, Quesneville H, Read B, Rensing SA, Ritter A, Rousvoal S, Samanta M, Samson G, Schroeder DC, Ségurens B, Strittmatter M, Tonon T, Tregear JW, Valentin K, von Dassow P, Yamagishi T, Van de Peer Y, Wincker P (2010) The Ectocarpus genome and the independent evolution of multicellularity in brown algae. Nature 465(7298):617–621

    Google Scholar 

  • Cho IH (2012) Effects of Panax ginseng in neurodegenerative diseases. J Ginseng Res 36:342

    Google Scholar 

  • Choi HI, Kim NH, Lee J, Choi BS, Kim KD, Park JY, Lee SC, Yang TJ (2013) Evolutionary relationship of Panax ginseng and P. quinquefolius inferred from sequencing and comparative analysis of expressed sequence tags. Genet Resour Crop Evol 60:1377–1387

    Google Scholar 

  • Choi HI, Waminal NE, Park HM, Kim NH, Choi BS, Park M, Choi D, Lim YP, Kwon SJ, Park BS, Kim HH, Yang TJ (2014) Major repeat components covering one-third of the ginseng (Panax ginseng C. A. Meyer) genome and evidence for allotetraploidy. Plant J 77:906–916

    Google Scholar 

  • Hegarty MJ, Hiscock SJ (2008) Genomic clues to the evolutionary success of polyploid plants. Curr Biol 18:R435-444

    Google Scholar 

  • Hong C, Lee S, Park J, Plaha P, Park Y, Lee Y, Choi J, Kim K, Lee J, Lee J (2004) Construction of a BAC library of Korean ginseng and initial analysis of BAC-end sequences. Mol Genet Genomics 271:709–716

    Google Scholar 

  • Jang W, Kim NH, Lee J, Waminal NE, Lee SC, Jayakodi M, Choi HI, Park JY, Lee JE, Yang TJ (2017) A glimpse of Panax ginseng genome structure revealed from ten BAC clone sequences obtained by SMRT sequencing platform. Plant Breed Biotechnol 5:25–35

    Google Scholar 

  • Jayakodi M, Lee SC, Park HS, Jang W, Lee YS, Choi BS, Nah GJ, Kim DS, Natesan S, Sun C, Yang TJ (2014) Transcriptome profiling and comparative analysis of Panax ginseng adventitious roots. J Ginseng Res 38(4):278–288

    Google Scholar 

  • Jayakodi M, Lee SC, Lee YS, Park HS, Kim NH, Jang W, Lee HO, Joh HJ, Yang TJ (2015) Comprehensive analysis of Panax ginseng root transcriptomes. BMC Plant Biol 15:138

    Google Scholar 

  • Jayakodi M, Choi BS, Lee SC, Kim NH, Park JY, Jang W, Lakshmanan M, Mohan SVG, Lee DY, Yang TJ (2018) Ginseng Genome Database: an open-access platform for genomics of Panax ginseng. BMC Plant Biol 18:62

    Google Scholar 

  • Kim K, Lee SC, Lee J, Lee HO, Joh HJ, Kim NH, Park HS, Yang TJ (2015) Comprehensive survey of genetic diversity in chloroplast genomes and 45S nrDNAs within Panax ginseng species. PLoS ONE 10(6):e0117159

    Google Scholar 

  • Kim K, Nguyen VB, Dong J, Wang Y, Park JY, Lee SC, Yang TJ (2017) Evolution of the Araliaceae family inferred from complete chloroplast genomes and 45S nrDNAs of 10 Panax-related species. Sci Rep 7:4917

    Google Scholar 

  • Kim NH, Choi HI, Ahn IO, Yang TJ (2014) Evidence of genome duplication revealed by sequence analysis of multi-loci expressed sequence tag-simple sequence repeat bands in Panax ginseng Meyer. J Ginseng Res 38:130–135

    Google Scholar 

  • Kim NH, Jayakodi M, Lee SC, Choi BS, Jang W, Lee J, Kim HH, Waminal NE, Lakshmanan M, Van Nguyen B, Lee YS, Park HS, Koo HJ, Park JY, Perumal S, Joh HJ, Lee H, Kim J, Kim IS, Kim K, Koduru L, Kang KB, Sung SH, Yu Y, Park DS, Choi D, Seo E, Kim S, Kim YC, Hyun DY, Park YI, Kim C, Lee TH, Kim HU, Soh MS, Lee Y, In JG, Kim HS, Kim YM, Yang DC, Wing RA, Lee DY, Paterson AH, Yang TJ (2018) Genome and evolution of the shade-requiring medicinal herb Panax ginseng. Plant Biotechnol J 16:1904–1917

    Google Scholar 

  • Lee J, Waminal NE, Choi HI, Perumal S, Lee SC, Nguyen VB, Jang W, Kim NH, Gao LZ, Yang TJ (2017) Rapid amplification of four retrotransposon families promoted speciation and genome size expansion in the genus Panax. Sci Rep 7:9045

    Google Scholar 

  • Leitch IJ, Bennett MD (1997) Polyploidy in angiosperms. Trends Plant Sci 2:470–476

    Google Scholar 

  • McClintock B (1978) Mechanisms that rapidly reorganize the genome. Stadler Genet Symp 10:25–48

    Google Scholar 

  • Nguyen VB, Giang VNL, Waminal NE, Park HS, Kim NH, Jang W, Lee J, Yang TJ (2018) Comprehensive comparative analysis of chloroplast genomes from seven Panax species and development of an authentication system based on species-unique SNP markers. J Ginseng Res https://doi.org/10.1016/j.jgr.2018.06.003

  • Obae SG, West TP (2012) Nuclear DNA content and genome size of American ginseng. J Med Plants Res 6:4719–4723

    Google Scholar 

  • Soltis DE (2005) Ancient and recent polyploidy in angiosperms. New Phytol 166:5–8

    Google Scholar 

  • Sterck L, Rombauts S, Jansson S, Sterky F, Rouze P, Van de Peer Y (2005) EST data suggest that poplar is an ancient polyploid. New Phytol 167:165–170

    Google Scholar 

  • Waminal NE, Choi HI, Kim NH, Jang WJ, Lee J, Park JY, Kim HH, Yang TJ (2017) A refined Panax ginseng karyotype based on an ultra-high copy 167-bp tandem repeat and ribosomal DNAs. J Ginseng Res 41:469–476

    Google Scholar 

  • Wen J, Plunkett GM, Mitch AD, Wagstaff SJ (2001) The evolution of araliaceae: a phylogenetic analysis based on ITS sequences of nuclear ribosomal DNA. Syst Bot 26:144–167

    Google Scholar 

  • Wong AS, Che CM, Leung KW (2015) Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview. Nat Prod Rep 32:256–272

    Google Scholar 

  • Xie JT, Mehendale SR, Li X, Quigg R, Wang X, Wang CZ, Wu JA, Aung HH, Bell GI, Yuan CS (2005) Anti-diabetic effect of ginsenoside Re in ob/ob mice. Biochem Biophys Acta 1740:319–325

    Google Scholar 

  • Xu J, Chu Y, Liao B, Xiao S, Yin Q, Bai R, Su H, Dong L, Li X, Qian J, Zhang J, Zhang Y, Zhang X, Wu M, Zhang J, Li G, Zhang L, Chang Z, Zhang Y, Jia Z, Liu Z, Afreh D, Nahurira R, Zhang L, Cheng R, Zhu Y, Zhu G, Rao W, Zhou C, Qiao L, Huang Z, Cheng YC, Chen S (2017) Panax ginseng genome examination for ginsenoside biosynthesis. Gigascience 6:1–15

    Google Scholar 

  • Zheng Sd, Wu HJ, Dl Wu (2012) Roles and mechanisms of ginseng in protecting heart. Chin J Integr Med 18:548–555

    Google Scholar 

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Correspondence to Tae-Jin Yang .

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Kim, NH., Jayakodi, M., Yang, TJ. (2021). Ginseng Genome Structure and Evolution. In: Xu, J., Yang, TJ., Hu, Hy. (eds) The Ginseng Genome. Compendium of Plant Genomes. Springer, Cham. https://doi.org/10.1007/978-3-030-30347-1_7

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