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Management of Barrett’s Esophagus: State of the Art

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Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy

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Abstract

The incidence of esophageal adenocarcinoma is rising, despite current screening and surveillance strategies for its premalignant condition – Barrett’s esophagus. Screening efforts are hindered, in part, by the lack of a well-defined population at risk as well as the costs of upper endoscopy, indicating the need for improved risk stratification and cost-efficient testing. Adequate surveillance has been challenging given the cumbersome biopsy protocols, missed lesions, and absence of individualized surveillance intervals. This chapter focuses on recent advances in noninvasive testing for Barrett’s screening, as well as, endoscopic imaging advances in surveillance that seem to offer promise in improving detection while hopefully driving down cost. We will also discuss medical treatment of Barrett’s as well as current knowledge in chemoprevention.

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Author information

Authors and Affiliations

  1. Division of Gastroenterology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

    Nour Hamade

  2. Department of Gastroenterology, Veterans Affairs Medical Center and University of Kansas School of Medicine, Kansas City, MO, USA

    Prateek Sharma

Authors
  1. Nour Hamade
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  2. Prateek Sharma
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Corresponding author

Correspondence to Prateek Sharma .

Editor information

Editors and Affiliations

  1. Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, MILANO, Milano, Italy

    Pier Alberto Testoni

  2. Digestive Diseases Center, Showa University Hospital, Tokyo, Japan

    Haruhiro Inoue

  3. Div. of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA

    Michael B. Wallace

Section Editor information

  1. Cancer Center, Mayo Clinic, Jacksonville, FL, USA

    Michael B. Wallace

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Hamade, N., Sharma, P. (2020). Management of Barrett’s Esophagus: State of the Art. In: Testoni, P.A., Inoue, H., Wallace, M.B. (eds) Gastrointestinal and Pancreatico-Biliary Diseases: Advanced Diagnostic and Therapeutic Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-030-29964-4_5-1

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  • DOI: https://doi.org/10.1007/978-3-030-29964-4_5-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29964-4

  • Online ISBN: 978-3-030-29964-4

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