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Antibiotic Stewardship Related to CDI in Long-Term Care Facilities

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Clostridium Difficile Infection in Long-Term Care Facilities
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Abstract

Antibiotic stewardship plays a key role in prevention of Clostridioides difficile colonization and infection. This chapter summarizes on the need for stewardship in long-term care facilities. It focuses on important elements in a stewardship program and provides guidance on ways to implement and sustain a stewardship program at any LTCF.

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References

  1. Dubberke ER, Olsen MA. Burden of Clostridium difficile on the healthcare system. Clin Infect Dis. 2012;55(Suppl 2):S88–92.

    Article  Google Scholar 

  2. Smith PW, Bennett G, Bradley S, Drinka P, Lautenbach E, Marx J, et al. SHEA/APIC guideline: infection prevention and control in the long-term care facility, July 2008. Infect Control Hosp Epidemiol. 2008;29(9):785–814.

    Article  Google Scholar 

  3. Chopra T, Goldstein EJ. Clostridium difficile infection in long-term care facilities: a call to action for antimicrobial stewardship. Clin Infect Dis. 2015;60(Suppl 2):S72–6.

    Article  Google Scholar 

  4. Pawar D, Tsay R, Nelson DS, Elumalai MK, Lessa FC, Clifford McDonald L, et al. Burden of Clostridium difficile infection in long-term care facilities in Monroe County, New York. Infect Control Hosp Epidemiol. 2012;33(11):1107–12.

    Article  Google Scholar 

  5. Carling P, Fung T, Killion A, Terrin N, Barza M. Favorable impact of a multidisciplinary antibiotic management program conducted during 7 years. Infect Control Hosp Epidemiol. 2003;24(9):699–706.

    Article  Google Scholar 

  6. Feazel LM, Malhotra A, Perencevich EN, Kaboli P, Diekema DJ, Schweizer ML. Effect of antibiotic stewardship programmers on Clostridium difficile incidence: a systematic review and meta-analysis. J Antimicrob Chemother. 2014;69(7):1748–54.

    Article  CAS  Google Scholar 

  7. Climo MW, Israel DS, Wong ES, Williams D, Coudron P, Markowitz SM. Hospital-wide restriction of clindamycin: effect on the incidence of Clostridium difficile-associated diarrhea and cost. Ann Intern Med. 1998;128(12 Pt 1):989–95.

    Article  CAS  Google Scholar 

  8. Centers for Disease Control and Prevention. Core elements of hospital antibiotic stewardship programs. Atlanta: US Department of Health and Human Services, CDC; 2014. Accessed 30 Sept 2014.

    Google Scholar 

  9. Morrill HJ, Caffrey AR, Jump RL, Dosa D, LaPlante KL. Antimicrobial stewardship in long-term care facilities: a call to action. J Am Med Dir Assoc. 2016;17(2):183. e1–16.

    Article  Google Scholar 

  10. Van Schooneveld T, Miller H, Sayles H, Watkins K, Smith PW. Survey of antimicrobial stewardship practices in Nebraska long-term care facilities. Infect Control Hosp Epidemiol. 2011;32(7):732–4.

    Article  Google Scholar 

  11. Morrill HJ, Mermel LA, Baier RR, Alexander-Scott N, Dosa D, Kavoosifar S, et al. Antimicrobial stewardship in Rhode Island long-term care facilities: current standings and future opportunities. Infect Control Hosp Epidemiol. 2016;37(8):979–82.

    Article  Google Scholar 

  12. Jump RLP, Gaur S, Katz MJ, Crnich CJ, Dumyati G, Ashraf MS, et al. Template for an antibiotic stewardship policy for post-acute and long-term care settings. J Am Med Dir Assoc. 2017;18(11):913–20.

    Article  Google Scholar 

  13. Zarowitz BJ, Allen C, Tangalos E, Ouslander JG. Algorithms promoting antimicrobial stewardship in long-term care. J Am Med Dir Assoc. 2016;17(2):173–8.

    Article  Google Scholar 

  14. Jump RL, Olds DM, Seifi N, Kypriotakis G, Jury LA, Peron EP, et al. Effective antimicrobial stewardship in a long-term care facility through an infectious disease consultation service: keeping a LID on antibiotic use. Infect Control Hosp Epidemiol. 2012;33(12):1185–92.

    Article  Google Scholar 

  15. Beaulac K, Corcione S, Epstein L, Davidson LE, Doron S. Antimicrobial stewardship in a long-term acute care hospital using offsite electronic medical record audit. Infect Control Hosp Epidemiol. 2016;37(4):433–9.

    Article  Google Scholar 

  16. Kullar R, Yang H, Grein J, Murthy R. A roadmap to implementing antimicrobial stewardship principles in long-term care facilities (LTCFs): collaboration between an acute-care hospital and LTCFs. Clin Infect Dis. 2018;66(8):1304–12.

    Article  Google Scholar 

  17. Nicolle LE. Infection prevention issues in long-term care. Curr Opin Infect Dis. 2014;27(4):363–9.

    Article  Google Scholar 

  18. Katz MJ, Gurses AP, Tamma PD, Cosgrove SE, Miller MA, Jump RLP. Implementing antimicrobial stewardship in long-term care settings: an integrative review using a human factors approach. Clin Infect Dis. 2017;65(11):1943–51.

    Article  Google Scholar 

  19. Brakovich B, Bonham E, VanBrackle L. War on the spore: Clostridium difficile disease among patients in a long-term acute care hospital. J Healthc Qual. 2013;35(3):15–21.

    Article  Google Scholar 

  20. Bunch M, Turley J, Johnson K. Antimicrobial stewardship and infection control practices reduced cost and healthcare facility-onset Clostridium difficile infection (HO-CDI) in a long-term acute care (LTAC) setting. Am J Infect Control. 2017;45(6):S18–9.

    Article  Google Scholar 

  21. Valiquette L, Cossette B, Garant MP, Diab H, Pepin J. Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain. Clin Infect Dis. 2007;45(Suppl 2):S112–21.

    Article  CAS  Google Scholar 

  22. Doernberg SB, Dudas V, Trivedi KK. Implementation of an antimicrobial stewardship program targeting residents with urinary tract infections in three community long-term care facilities: a quasi-experimental study using time-series analysis. Antimicrob Resist Infect Control. 2015;4:54.

    Article  Google Scholar 

  23. Pate PG, Storey DF, Baum DL. Implementation of an antimicrobial stewardship program at a 60-bed long-term acute care hospital. Infect Control Hosp Epidemiol. 2012;33(4):405–8.

    Article  Google Scholar 

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Navalkele, B.D. (2020). Antibiotic Stewardship Related to CDI in Long-Term Care Facilities. In: Chopra, T. (eds) Clostridium Difficile Infection in Long-Term Care Facilities. Springer, Cham. https://doi.org/10.1007/978-3-030-29772-5_7

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  • DOI: https://doi.org/10.1007/978-3-030-29772-5_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29771-8

  • Online ISBN: 978-3-030-29772-5

  • eBook Packages: MedicineMedicine (R0)

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