Skip to main content
  • 1201 Accesses

Abstract

Definition: Multiple or plasma cell myeloma (PCM) is a bone marrow-based multifocal plasma cell neoplasm, usually associated with secretion of a single homogeneous monoclonal immunoglobulin called M protein. The bone marrow is the site of origin of nearly all PCMs. Multifocal bone marrow involvement is frequently observed. In advanced disease, extramedullary involvement can be appreciated.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Selected Bibliography

  • Dimopoulos M, Terpos E, Comenzo RL, Tosi P, Beksac M, Sezer O, Siegel D, Lokhorst H, Kumar S, Rajkumar SV, Niesvizky R, Moulopoulos LA, Durie BG, IMWG. International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma. Leukemia. 2009;23(9):1545–56.

    Article  CAS  Google Scholar 

  • Harousseau JL. Multiple myeloma in the elderly: when to treat, when to go to transplant. Oncology (Williston Park). 2010;24(11):992–8, Review.

    Google Scholar 

  • Kumar A, Galeb S, Djulbegovic B. Treatment of patients with multiple myeloma: an overview of systematic reviews. Acta Haematol. 2011;125(1–2):8–22, Review.

    Article  CAS  Google Scholar 

  • Nahi H, Sutlu T, Jansson M, Alici E, Gahrton G. Clinical impact of chromosomal aberrations in multiple myeloma. J Intern Med. 2011;269(2):137–47.

    Article  CAS  Google Scholar 

  • Palumbo A, Anderson K. Multiple myeloma. N Engl J Med. 2011;364(11):1046–60.

    Article  CAS  Google Scholar 

  • Rajkumar SV. Multiple myeloma: 2011 update on diagnosis, risk-stratification, and management. Am J Hematol. 2011;86(1):57–65, Review.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Marta Sbaraglia .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Sbaraglia, M. (2020). Multiple Myeloma. In: Picci, P., et al. Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions. Springer, Cham. https://doi.org/10.1007/978-3-030-29676-6_53

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-29676-6_53

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-29675-9

  • Online ISBN: 978-3-030-29676-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics